(Q38916622)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25619836%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

title

Three-dimensional microenvironment confers enhanced sensitivity to doxorubicin by reducing p53-dependent induction of autophagy (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25619836%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

0 references

1 reference

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25619836%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

author name string

L R Gomes

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25619836%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

A T Vessoni

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25619836%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

language of work or name

English

0 references

publication date

26 January 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25619836%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25619836%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

volume

34

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25619836%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

issue

42

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25619836%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

page(s)

5329-5340

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25619836%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/onc.2014.461

28 February 2020

exact match

0 references

cites work

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Suppression of autophagy sensitizes multidrug resistant cells towards Src tyrosine kinase specific inhibitor PP2.

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DRAM, a p53-induced modulator of autophagy, is critical for apoptosis

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21 January 2018

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The morphologies of breast cancer cell lines in three-dimensional assays correlate with their profiles of gene expression.

21 January 2018

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Downregulation of VRK1 by p53 in response to DNA damage is mediated by the autophagic pathway

21 January 2018

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Doxorubicin as a molecular nanotheranostic agent: effect of doxorubicin encapsulation in micelles or nanoemulsions on the ultrasound-mediated intracellular delivery and nuclear trafficking

21 January 2018

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Three-dimensional overlay culture models of human breast cancer reveal a critical sensitivity to mitogen-activated protein kinase kinase inhibitors

21 January 2018

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Pharmacokinetics of doxorubicin administered i.v. as Myocet (TLC D-99; liposome-encapsulated doxorubicin citrate) compared with conventional doxorubicin when given in combination with cyclophosphamide in patients with metastatic breast cancer

21 January 2018

1 reference

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Autophagy protects breast cancer cells from epirubicin-induced apoptosis and facilitates epirubicin-resistance development

21 January 2018

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How to interpret LC3 immunoblotting

21 January 2018

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The relative roles of DNA damage induced by UVA irradiation in human cells

21 January 2018

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Both XPA and DNA polymerase eta are necessary for the repair of doxorubicin-induced DNA lesions.

21 January 2018

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Caspase-3 enhances lung metastasis and cell migration in a protease-independent mechanism through the ERK pathway

21 January 2018

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Overexpression of Atg5 in mice activates autophagy and extends lifespan

21 January 2018

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Differential sensitivity of malignant glioma cells to methylating and chloroethylating anticancer drugs: p53 determines the switch by regulating xpc, ddb2, and DNA double-strand breaks.

21 January 2018

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Revisiting p53 for cancer-specific chemo- and radiotherapy: ten years after

21 January 2018

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p53 in breast cancer subtypes and new insights into response to chemotherapy

21 January 2018

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The inhibition of autophagy sensitises colon cancer cells with wild-type p53 but not mutant p53 to topotecan treatment

21 January 2018

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p53-dependent regulation of autophagy protein LC3 supports cancer cell survival under prolonged starvation.

21 January 2018

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STAT3-mediated autophagy dependence identifies subtypes of breast cancer where autophagy inhibition can be efficacious

21 January 2018

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Autophagy inhibition sensitizes colon cancer cells to antiangiogenic and cytotoxic therapy

21 January 2018

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Principles and current strategies for targeting autophagy for cancer treatment

21 January 2018

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Autophagy inhibition for chemosensitization and radiosensitization in cancer: do the preclinical data support this therapeutic strategy?

21 January 2018

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21 January 2018

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Inhibition of integrin-mediated crosstalk with epidermal growth factor receptor/Erk or Src signaling pathways in autophagic prostate epithelial cells induces caspase-independent death

21 January 2018

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21 January 2018

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Collagen-IV and laminin-1 regulate estrogen receptor alpha expression and function in mouse mammary epithelial cells

21 January 2018

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Detachment-induced autophagy during anoikis and lumen formation in epithelial acini.

21 January 2018

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Extracellular matrix regulation of autophagy

21 January 2018

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Induction of autophagy during extracellular matrix detachment promotes cell survival

21 January 2018

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DRAM links autophagy to p53 and programmed cell death

21 January 2018

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p53 Regulates oxidative stress-mediated retrograde signaling: a novel mechanism for chemotherapy-induced cardiac injury

21 January 2018

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p53-mediated senescence impairs the apoptotic response to chemotherapy and clinical outcome in breast cancer.

21 January 2018

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21 January 2018

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21 January 2018

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The role of p53 in DNA damage-mediated cytotoxicity overrides its ability to regulate nucleotide excision repair in human fibroblasts

21 January 2018

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MCF-7 cells as a three-dimensional model for the study of human breast cancer

21 January 2018

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Gap-filling and bypass at the replication fork are both active mechanisms for tolerance of low-dose ultraviolet-induced DNA damage in the human genome.

21 January 2018

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21 January 2018

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TGF-β1 modulates the homeostasis between MMPs and MMP inhibitors through p38 MAPK and ERK1/2 in highly invasive breast cancer cells

21 January 2018

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Analyzing real-time PCR data by the comparative C(T) method

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.461

Effects of the chemotherapeutic agent doxorubicin on the protein C anticoagulant pathway

21 January 2018

1 reference

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Tissue structure, nuclear organization, and gene expression in normal and malignant breast

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25619836

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Safety and efficacy of the multidrug-resistance inhibitor biricodar (VX-710) with concurrent doxorubicin in patients with anthracycline-resistant advanced soft tissue sarcoma

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25619836

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/ONC.2014.461

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25619836%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

28 February 2020

1008216401

0 references

Fatcat ID

release_j4mh7lzsdzc7ndqgt3cxblmjne

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/j4mh7lzsdzc7ndqgt3cxblmjne

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25619836%20AND%20SRC:MED&resulttype=core&format=json