(Q38947516)

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α-Synuclein-induced mitochondrial dysfunction in isolated preparation and intact cells: implications in the pathogenesis of Parkinson's disease

scientific article published on 18 November 2014

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7 September 2017

α-Synuclein-induced mitochondrial dysfunction in isolated preparation and intact cells: implications in the pathogenesis of Parkinson's disease (English)

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Europe PubMed Central

PubMed publication ID

7 September 2017

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Vineet Kumar Khemka

4

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6 June 2020

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6 June 2020

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Aritri Bir

1

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6 June 2020

Oishimaya Sen

2

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6 June 2020

Shruti Anand

3

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6 June 2020

Priyanjalee Banerjee

5

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6 June 2020

Arghyadip Sahoo

7

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6 June 2020

Sasanka Chakrabarti

8

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6 June 2020

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18 November 2014

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7 September 2017

Journal of Neurochemistry

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6 June 2020

131

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6 June 2020

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6 June 2020

868-877

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6 June 2020

The molecular composition of the mitochondrial permeability transition pore

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12966

21 January 2018

Alpha-synuclein induced membrane depolarization and loss of phosphorylation capacity of isolated rat brain mitochondria: implications in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12966

21 January 2018

TOM40 mediates mitochondrial dysfunction induced by α-synuclein accumulation in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12966

21 January 2018

The role of alpha-synuclein in neurodegenerative diseases

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12966

21 January 2018

Recent progress on regulation of the mitochondrial permeability transition pore; a cyclosporin-sensitive pore in the inner mitochondrial membrane

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12966

21 January 2018

Alpha-synuclein overexpression increases dopamine toxicity in BE2-M17 cells

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12966

21 January 2018

Stages in the development of Parkinson's disease-related pathology

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12966

21 January 2018

alpha-Synuclein and neuronal cell death

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12966

21 January 2018

Cell systems and the toxic mechanism(s) of alpha-synuclein

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12966

21 January 2018

The mitochondrial permeability transition pore and its role in cell death

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12966

21 January 2018

alpha-Synuclein protects against oxidative stress via inactivation of the c-Jun N-terminal kinase stress-signaling pathway in neuronal cells

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12966

21 January 2018

Ageing, neurodegeneration and Parkinson's disease

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12966

21 January 2018

Two different binding modes of α-synuclein to lipid vesicles depending on its aggregation state

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12966

21 January 2018

Mitochondrial dysfunction mediated by quinone oxidation products of dopamine: Implications in dopamine cytotoxicity and pathogenesis of Parkinson's disease

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12966

21 January 2018

Human alpha-synuclein over-expression increases intracellular reactive oxygen species levels and susceptibility to dopamine.

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12966

21 January 2018

Mitochondrial permeability transition: a common pathway to necrosis and apoptosis

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12966

21 January 2018

Dieldrin promotes proteolytic cleavage of poly(ADP-ribose) polymerase and apoptosis in dopaminergic cells: protective effect of mitochondrial anti-apoptotic protein Bcl-2.

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12966

21 January 2018

Sensitization of neuronal cells to oxidative stress with mutated human alpha-synuclein

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12966

21 January 2018

Effect of the overexpression of wild-type or mutant alpha-synuclein on cell susceptibility to insult

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12966

21 January 2018

The mitochondrial permeability transition in cell death: a common mechanism in necrosis, apoptosis and autophagy

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12966

21 January 2018

Phosphorylated alpha-synuclein at Ser-129 is targeted to the proteasome pathway in a ubiquitin-independent manner

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12966

21 January 2018

Dopaminergic loss and inclusion body formation in alpha-synuclein mice: implications for neurodegenerative disorders

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12966

21 January 2018

Mitochondrial impairment as an early event in the process of apoptosis induced by glutathione depletion in neuronal cells: relevance to Parkinson's disease

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12966

21 January 2018

α-Synuclein and mitochondria: partners in crime?

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12966

21 January 2018

Alpha-synuclein overexpression and aggregation exacerbates impairment of mitochondrial functions by augmenting oxidative stress in human neuroblastoma cells

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12966

21 January 2018

The interplay between lipids and dopamine on α-synuclein oligomerization and membrane binding.

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12966

21 January 2018

alpha-synuclein is required for the fibrillar nature of ubiquitinated inclusions induced by proteasomal inhibition in primary neurons.

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12966

21 January 2018

Membrane Permeabilization by Oligomeric α-Synuclein: In Search of the Mechanism

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12966

21 January 2018

Inducible expression of mutant alpha-synuclein decreases proteasome activity and increases sensitivity to mitochondria-dependent apoptosis

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12966

21 January 2018

alpha-synuclein metabolism and aggregation is linked to ubiquitin-independent degradation by the proteasome

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12966

21 January 2018

Vesicle permeabilization by protofibrillar alpha-synuclein: implications for the pathogenesis and treatment of Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12966

21 January 2018

Curcumin reduces alpha-synuclein induced cytotoxicity in Parkinson's disease cell model

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12966

21 January 2018

Epidemiology and etiology of Parkinson's disease: a review of the evidence

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12966

21 January 2018

α-Synuclein and neuronal cell death

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12966

21 January 2018

Aggregated alpha-synuclein activates microglia: a process leading to disease progression in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12966

21 January 2018

Reactive oxygen species (ROS)-induced ROS release: a new phenomenon accompanying induction of the mitochondrial permeability transition in cardiac myocytes

1 reference

https://api.crossref.org/works/10.1111%2FJNC.12966

21 January 2018

Identifiers

10.1111/JNC.12966

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25319443%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25319443%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

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