(Q38954615)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27629140%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

review article

1 reference

title

Emerging tale of UPR and cancer: an essentiality for malignancy (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27629140%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27629140%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

author name string

Younis Mohammad Hazari

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27629140%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

Arif Bashir

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27629140%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

Ehtisham Ul Haq

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27629140%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

publication date

14 September 2016

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27629140%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27629140%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

volume

37

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27629140%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

issue

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27629140%20AND%20SRC:MED&resulttype=core&format=json

23 March 2020

page(s)

14381-14390

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27629140%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1007/s13277-016-5343-0

23 March 2020

exact match

0 references

cites work

Regulatory crosstalk within the mammalian unfolded protein response

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Roles of N-linked glycans in the endoplasmic reticulum

21 January 2018

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Endoplasmic reticulum stress responses

21 January 2018

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The endoplasmic reticulum: a multifunctional signaling organelle

21 January 2018

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Molecular chaperones and proteostasis regulation during redox imbalance

21 January 2018

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Novel variants of SERPIN1A gene: Interplay between alpha1-antitrypsin deficiency and chronic obstructive pulmonary disease

21 January 2018

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Endoplasmic reticulum quality control in cancer: Friend or foe.

21 January 2018

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Novel roles of the unfolded protein response in the control of tumor development and aggressiveness.

21 January 2018

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Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response.

21 January 2018

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The endoribonuclease activity of mammalian IRE1 autoregulates its mRNA and is required for the unfolded protein response

21 January 2018

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IRE1alpha kinase activation modes control alternate endoribonuclease outputs to determine divergent cell fates.

21 January 2018

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Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response

21 January 2018

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Roles of the translation initiation factor eIF2α serine 51 phosphorylation in cancer formation and treatment

21 January 2018

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Translational control in stress and apoptosis

21 January 2018

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ER stress-induced cell death mechanisms

21 January 2018

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Phosphorylation of eIF2alpha in response to 26S proteasome inhibition is mediated by the haem-regulated inhibitor (HRI) kinase.

21 January 2018

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ATF6 upregulates XBP1S and inhibits ER stress-mediated apoptosis in osteoarthritis cartilage

21 January 2018

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Distinct roles of activating transcription factor 6 (ATF6) and double-stranded RNA-activated protein kinase-like endoplasmic reticulum kinase (PERK) in transcription during the mammalian unfolded protein response

21 January 2018

1 reference

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Tumor Hypoxia and Heterogeneity: Challenges and Opportunities for the Future

21 January 2018

1 reference

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ER proteostasis addiction in cancer biology: Novel concepts

21 January 2018

1 reference

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Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours

21 January 2018

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Perk-dependent translational regulation promotes tumor cell adaptation and angiogenesis in response to hypoxic stress

21 January 2018

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Two phases of disulfide bond formation have differing requirements for oxygen.

21 January 2018

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The FAD- and O(2)-dependent reaction cycle of Ero1-mediated oxidative protein folding in the endoplasmic reticulum

21 January 2018

1 reference

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Hypoxia-inducible factors in physiology and medicine

21 January 2018

1 reference

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Hypoxia-inducible factor-1 modulates gene expression in solid tumors and influences both angiogenesis and tumor growth.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-016-5343-0

Unifying theory of hypoxia tolerance: molecular/metabolic defense and rescue mechanisms for surviving oxygen lack.

21 January 2018

1 reference

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Regulation of protein synthesis by hypoxia via activation of the endoplasmic reticulum kinase PERK and phosphorylation of the translation initiation factor eIF2alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-016-5343-0

Activating transcription factor 4 is translationally regulated by hypoxic stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-016-5343-0

The PERK/eIF2alpha/ATF4 module of the UPR in hypoxia resistance and tumor growth

21 January 2018

1 reference

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ER stress-regulated translation increases tolerance to extreme hypoxia and promotes tumor growth

21 January 2018

1 reference

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Anoxic induction of ATF-4 through HIF-1-independent pathways of protein stabilization in human cancer cells

21 January 2018

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The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5.

21 January 2018

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Transcriptional up-regulation of ULK1 by ATF4 contributes to cancer cell survival.

21 January 2018

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PERK/eIF2α signaling protects therapy resistant hypoxic cells through induction of glutathione synthesis and protection against ROS.

21 January 2018

1 reference

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XBP1 is essential for survival under hypoxic conditions and is required for tumor growth.

21 January 2018

1 reference

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XBP1 promotes triple-negative breast cancer by controlling the HIF1α pathway

21 January 2018

1 reference

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Endoplasmic reticulum (ER) stress and hypoxia response pathways interact to potentiate hypoxia-inducible factor 1 (HIF-1) transcriptional activity on targets like vascular endothelial growth factor (VEGF)

21 January 2018

1 reference

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Sustained IRE1 and ATF6 signaling is important for survival of melanoma cells undergoing ER stress

21 January 2018

1 reference

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Inhibition of ER stress-associated IRE-1/XBP-1 pathway reduces leukemic cell survival

21 January 2018

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Transformation-associated gene regulation by ATF6alpha during hepatocarcinogenesis

21 January 2018

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Hallmarks of Cancer: The Next Generation

21 January 2018

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Translational control and the unfolded protein response

21 January 2018

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The GCN2 eIF2alpha kinase is required for adaptation to amino acid deprivation in mice

21 January 2018

1 reference

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Elevated ATF4 expression, in the absence of other signals, is sufficient for transcriptional induction via CCAAT enhancer-binding protein-activating transcription factor response elements

21 January 2018

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Identification of positive-acting domains in GCN2 protein kinase required for translational activation of GCN4 expression

21 January 2018

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The histidyl-tRNA synthetase-related sequence in the eIF-2 alpha protein kinase GCN2 interacts with tRNA and is required for activation in response to starvation for different amino acids

21 January 2018

1 reference

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The unfolded protein response induces the angiogenic switch in human tumor cells through the PERK/ATF4 pathway

21 January 2018

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Amino acid deprivation promotes tumor angiogenesis through the GCN2/ATF4 pathway

21 January 2018

1 reference

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Is cancer a disease of abnormal cellular metabolism? New angles on an old idea

21 January 2018

1 reference

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Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism

21 January 2018

1 reference

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Dynamic O-GlcNAc modification of nucleocytoplasmic proteins in response to stress. A survival response of mammalian cells

21 January 2018

1 reference

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ER stress and hexosamine pathway during tumourigenesis: A pas de deux?

21 January 2018

1 reference

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Nutrient sensor O-GlcNAc transferase regulates breast cancer tumorigenesis through targeting of the oncogenic transcription factor FoxM1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-016-5343-0

GlcNAcylation plays an essential role in breast cancer metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-016-5343-0

Critical role of O-Linked β-N-acetylglucosamine transferase in prostate cancer invasion, angiogenesis, and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-016-5343-0

O-GlcNAcylation is a novel regulator of lung and colon cancer malignancy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-016-5343-0

O-linked β-N-acetylglucosaminylation (O-GlcNAcylation) in primary and metastatic colorectal cancer clones and effect of N-acetyl-β-D-glucosaminidase silencing on cell phenotype and transcriptome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-016-5343-0

O-GlcNAcylation plays a role in tumor recurrence of hepatocellular carcinoma following liver transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-016-5343-0

Aberrant O-GlcNAcylation characterizes chronic lymphocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-016-5343-0

Altered tumor-cell glycosylation promotes metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-016-5343-0

Immature truncated O-glycophenotype of cancer directly induces oncogenic features

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-016-5343-0

Deficiency in glutamine but not glucose induces MYC-dependent apoptosis in human cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-016-5343-0

Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-016-5343-0

c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-016-5343-0

Strengthened glycolysis under hypoxia supports tumor symbiosis and hexosamine biosynthesis in pancreatic adenocarcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-016-5343-0

The emerging roles of forkhead box (Fox) proteins in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-016-5343-0

Hyper-O-GlcNAcylation is anti-apoptotic and maintains constitutive NF-κB activity in pancreatic cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-016-5343-0

Snail1 is stabilized by O-GlcNAc modification in hyperglycaemic condition

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-016-5343-0

Spliced X-box binding protein 1 couples the unfolded protein response to hexosamine biosynthetic pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-016-5343-0

Hexosamine pathway metabolites enhance protein quality control and prolong life.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-016-5343-0

X box-binding protein 1 regulates angiogenesis in human pancreatic adenocarcinomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-016-5343-0

Transcriptional regulation of VEGF-A by the unfolded protein response pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-016-5343-0

Inositol-requiring enzyme 1alpha is a key regulator of angiogenesis and invasion in malignant glioma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-016-5343-0

VEGF Signals through ATF6 and PERK to promote endothelial cell survival and angiogenesis in the absence of ER stress.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-016-5343-0

A novel ER stress-independent function of the UPR in angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-016-5343-0

21 January 2018

DNA damage and repair

1 reference

https://api.crossref.org/works/10.1007%2FS13277-016-5343-0

ER stress suppresses DNA double-strand break repair and sensitizes tumor cells to ionizing radiation by stimulating proteasomal degradation of Rad51.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-016-5343-0

Hypoxic activation of the PERK/eIF2α arm of the unfolded protein response promotes metastasis through induction of LAMP3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-016-5343-0

Hypoxic activation of the unfolded protein response (UPR) induces expression of the metastasis-associated gene LAMP3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-016-5343-0

Hypoxia stimulates migration of breast cancer cells via the PERK/ATF4/LAMP3-arm of the unfolded protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-016-5343-0

The PERK/ATF4/LAMP3-arm of the unfolded protein response affects radioresistance by interfering with the DNA damage response.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-016-5343-0

Hypoxic regulation of the PERK/ATF4/LAMP3-arm of the unfolded protein response in head and neck squamous cell carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-016-5343-0

Autocrine control of glioma cells adhesion and migration through IRE1α-mediated cleavage of SPARC mRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-016-5343-0

Transmission of endoplasmic reticulum stress and pro-inflammation from tumor cells to myeloid cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-016-5343-0

Cytokine-based transformation of immune surveillance into tumor-promoting inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-016-5343-0

MYC on the path to cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-016-5343-0

ER stress-mediated autophagy promotes Myc-dependent transformation and tumor growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-016-5343-0

Oncogenes strike a balance between cellular growth and homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-016-5343-0

Deregulated Myc requires MondoA/Mlx for metabolic reprogramming and tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-016-5343-0

Cancer-associated IDH1 mutations produce 2-hydroxyglutarate

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-016-5343-0

ATF4 regulates MYC-mediated neuroblastoma cell death upon glutamine deprivation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-016-5343-0

Anti-oncogenic role of the endoplasmic reticulum differentially activated by mutations in the MAPK pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-016-5343-0

Human cutaneous melanoma; a review of NRAS and BRAF mutation frequencies in relation to histogenetic subclass and body site

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-016-5343-0

Oncogenic BRAF induces chronic ER stress condition resulting in increased basal autophagy and apoptotic resistance of cutaneous melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-016-5343-0

Targeting ER stress-induced autophagy overcomes BRAF inhibitor resistance in melanoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-016-5343-0

Oncogenic activation of MEK/ERK primes melanoma cells for adaptation to endoplasmic reticulum stress.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-016-5343-0

Treatment of HER2-positive breast cancer: current status and future perspectives.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-016-5343-0

A pathway-based approach for identifying biomarkers of tumor progression to trastuzumab-resistant breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-016-5343-0

Natural osmolytes alleviate GRP78 and ATF-4 levels: Corroboration for potential modulators of unfolded protein response.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13277-016-5343-0

SPARC-induced migration of glioblastoma cell lines via uPA-uPAR signaling and activation of small GTPase RhoA.

21 January 2018

1 reference

12 December 2020

Tumour necrosis factor receptor 1 mediates endoplasmic reticulum stress-induced activation of the MAP kinase JNK

1 reference

12 December 2020

Growth arrest and DNA damage-inducible protein GADD34 targets protein phosphatase 1 alpha to the endoplasmic reticulum and promotes dephosphorylation of the alpha subunit of eukaryotic translation initiation factor 2

1 reference

12 December 2020

Deregulation of glucose transporter 1 and glycolytic gene expression by c-Myc

1 reference

12 December 2020

Endoplasmic reticulum chaperones and oxidoreductases: critical regulators of tumor cell survival and immunorecognition

1 reference

12 December 2020

Hypoxia-inducible factor-1alpha is a positive factor in solid tumor growth.

1 reference

12 December 2020

Cycling hypoxia and free radicals regulate angiogenesis and radiotherapy response

1 reference

12 December 2020

Insights from transgenic mouse models of ERBB2-induced breast cancer

1 reference

12 December 2020

Signaling in control of cell growth and metabolism

1 reference

12 December 2020

ATF6 is a transcription factor specializing in the regulation of quality control proteins in the endoplasmic reticulum

1 reference

12 December 2020

Hypoxia signalling through mTOR and the unfolded protein response in cancer

1 reference

12 December 2020

10.1007/S13277-016-5343-0

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27629140%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

23 March 2020

1038858057

0 references

Fatcat ID

release_sfutqclm5razndqpbvukeke6t4

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/sfutqclm5razndqpbvukeke6t4

24 November 2022

mapped directly with Wikidata item

1 reference