(Q39114297)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23921951%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

title

Oncogenic activation of MEK/ERK primes melanoma cells for adaptation to endoplasmic reticulum stress (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23921951%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

main subject

endoplasmic reticulum

0 references

author

Lei Jin

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23921951%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

Helen Rizos

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23921951%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

Xu Dong Zhang

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23921951%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

author name string

Amanda Croft

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23921951%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

Kwang H Tay

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23921951%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

Suzanah C Boyd

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23921951%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

Su T Guo

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23921951%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

Chen C Jiang

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23921951%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

Fritz Lai

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23921951%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

Hsin-Yi Tseng

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23921951%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

Peter Hersey

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23921951%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

language of work or name

English

0 references

publication date

6 August 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23921951%20AND%20SRC:MED&resulttype=core&format=json

Journal of Investigative Dermatology

7 March 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23921951%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

volume

134

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23921951%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23921951%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

page(s)

488-497

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23921951%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/jid.2013.325

7 March 2020

exact match

0 references

cites work

IRE1 signaling affects cell fate during the unfolded protein response

1 reference

12 December 2020

IGFBP7 is not required for B-RAF-induced melanocyte senescence

1 reference

12 December 2020

Suppression of PP2A is critical for protection of melanoma cells upon endoplasmic reticulum stress

1 reference

12 December 2020

Vemurafenib potently induces endoplasmic reticulum stress-mediated apoptosis in BRAFV600E melanoma cells

1 reference

12 December 2020

The mammalian unfolded protein response

1 reference

12 December 2020

Human cutaneous melanoma; a review of NRAS and BRAF mutation frequencies in relation to histogenetic subclass and body site

1 reference

12 December 2020

Up-regulation of Mcl-1 is critical for survival of human melanoma cells upon endoplasmic reticulum stress.

1 reference

12 December 2020

Translation regulation as a therapeutic target in cancer

1 reference

12 December 2020

Current strategies in overcoming resistance of cancer cells to apoptosis melanoma as a model.

1 reference

12 December 2020

GRP78 induction in cancer: therapeutic and prognostic implications.

1 reference

12 December 2020

Endoplasmic reticulum stress response in cancer: molecular mechanism and therapeutic potential.

1 reference

12 December 2020

Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity

1 reference

12 December 2020

Mutations of the BRAF gene in human cancer

1 reference

12 December 2020

Potent and selective inhibitors of the inositol-requiring enzyme 1 endoribonuclease

1 reference

12 December 2020

The mechanism of eukaryotic translation initiation and principles of its regulation

1 reference

12 December 2020

Targeting Mnks for cancer therapy

1 reference

12 December 2020

High frequency of BRAF mutations in nevi

1 reference

12 December 2020

Benign nodal nevi frequently harbor the activating V600E BRAF mutation

1 reference

12 December 2020

Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress

1 reference

12 December 2020

Human melanoma cells under endoplasmic reticulum stress acquire resistance to microtubule-targeting drugs through XBP-1-mediated activation of Akt.

1 reference

12 December 2020

Inhibition of MEK sensitizes human melanoma cells to endoplasmic reticulum stress-induced apoptosis

1 reference

12 December 2020

Induction of autophagy and inhibition of melanoma growth in vitro and in vivo by hyperactivation of oncogenic BRAF.

1 reference

12 December 2020

Translational control of cell fate: from integration of environmental signals to breaching anticancer defense.

1 reference

12 December 2020

RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growth

1 reference

12 December 2020

2-Deoxy-D-glucose enhances TRAIL-induced apoptosis in human melanoma cells through XBP-1-mediated up-regulation of TRAIL-R2

1 reference

12 December 2020

Endoplasmic reticulum stress: cell life and death decisions.

1 reference

12 December 2020

The eIF4E/eIF4G interaction inhibitor 4EGI-1 augments TRAIL-mediated apoptosis through c-FLIP Down-regulation and DR5 induction independent of inhibition of cap-dependent protein translation

1 reference

12 December 2020

MEK-independent survival of B-RAFV600E melanoma cells selected for resistance to apoptosis induced by the RAF inhibitor PLX4720.

1 reference

12 December 2020

The role of the unfolded protein response in tumour development: friend or foe?

1 reference

12 December 2020

Regulation of translation initiation in eukaryotes: mechanisms and biological targets

1 reference

12 December 2020

Mutation-driven drug development in melanoma

1 reference

12 December 2020

Protein phosphatase 2A as a potential target for anticancer therapy.

1 reference

12 December 2020

PI(4,5)P2 5-phosphatase A regulates PI3K/Akt signalling and has a tumour suppressive role in human melanoma

1 reference

12 December 2020

Apoptosis of human melanoma cells induced by inhibition of B-RAFV600E involves preferential splicing of bimS

1 reference

12 December 2020

Mechanisms of translational deregulation in human tumors and therapeutic intervention strategies.

1 reference

12 December 2020

Selective involvement of BH3-only proteins and differential targets of Noxa in diverse apoptotic pathways

1 reference

12 December 2020

Apoptosis induction in human melanoma cells by inhibition of MEK is caspase-independent and mediated by the Bcl-2 family members PUMA, Bim, and Mcl-1.

1 reference

12 December 2020

Adaptation to ER stress as a driver of malignancy and resistance to therapy in human melanoma

1 reference

12 December 2020

Anti-oncogenic role of the endoplasmic reticulum differentially activated by mutations in the MAPK pathway.

1 reference

12 December 2020

The unfolded protein response regulator GRP78/BiP is required for endoplasmic reticulum integrity and stress-induced autophagy in mammalian cells

1 reference

12 December 2020

Oncogenic Braf induces melanocyte senescence and melanoma in mice

1 reference

12 December 2020

eIF-4E expression and its role in malignancies and metastases.

1 reference

12 December 2020

Oncogenic BRAF is required for tumor growth and maintenance in melanoma models

1 reference

12 December 2020

The impact of the unfolded protein response on human disease

1 reference

12 December 2020

Oncogene-induced senescence does not require the p16(INK4a) or p14ARF melanoma tumor suppressors.

1 reference

12 December 2020

Translational control in cancer.

1 reference

12 December 2020

Cellular response to endoplasmic reticulum stress: a matter of life or death

1 reference

12 December 2020

CEP-32496: a novel orally active BRAF(V600E) inhibitor with selective cellular and in vivo antitumor activity

1 reference

12 December 2020

ER stress triggers apoptosis by activating BH3-only protein Bim

1 reference

12 December 2020

Small-molecule inhibition of the interaction between the translation initiation factors eIF4E and eIF4G

1 reference

12 December 2020

PP2A: the expected tumor suppressor

1 reference

12 December 2020

Glucose-regulated protein 78 antagonizes cisplatin and adriamycin in human melanoma cells.

1 reference

12 December 2020

B56-containing PP2A dephosphorylate ERK and their activity is controlled by the early gene IEX-1 and ERK

1 reference

12 December 2020

Lactate dehydrogenase 5 expression in melanoma increases with disease progression and is associated with expression of Bcl-XL and Mcl-1, but not Bcl-2 proteins

1 reference

12 December 2020

The unfolded protein response: from stress pathway to homeostatic regulation

1 reference

12 December 2020

IEX-1: a new ERK substrate involved in both ERK survival activity and ERK activation

1 reference

12 December 2020

MNK1 and EIF4E are downstream effectors of MEKs in the regulation of the nuclear export of HDM2 mRNA.

1 reference

12 December 2020

Human melanoma cells under endoplasmic reticulum stress are more susceptible to apoptosis induced by the BH3 mimetic obatoclax.

1 reference

12 December 2020

Transcriptional and translational control in the Mammalian unfolded protein response

1 reference

12 December 2020

BRAFE600-associated senescence-like cell cycle arrest of human naevi

1 reference

12 December 2020