Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q36580838)
Watch
English
Current strategies in overcoming resistance of cancer cells to apoptosis melanoma as a model.
scientific article published on January 2006
In more languages
edit
Statements
instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
16939779
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16939779%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 December 2019
review article
1 reference
stated in
Europe PubMed Central
title
Current strategies in overcoming resistance of cancer cells to apoptosis melanoma as a model
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
16939779
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16939779%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 December 2019
author
Xu Dong Zhang
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed publication ID
16939779
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16939779%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 December 2019
author name string
Peter Hersey
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
16939779
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16939779%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 December 2019
L Zhuang
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
16939779
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16939779%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 December 2019
publication date
1 January 2006
1 reference
stated in
Europe PubMed Central
PubMed publication ID
16939779
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16939779%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 December 2019
published in
International Review of Cytology
1 reference
stated in
Europe PubMed Central
PubMed publication ID
16939779
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16939779%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 December 2019
volume
251
1 reference
stated in
Europe PubMed Central
PubMed publication ID
16939779
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16939779%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 December 2019
page(s)
131-158
1 reference
stated in
Europe PubMed Central
PubMed publication ID
16939779
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16939779%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 December 2019
cites work
A Phase II trial of aprinocarsen, an antisense oligonucleotide inhibitor of protein kinase C alpha, administered as a 21-day infusion to patients with advanced ovarian carcinoma.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Augmenting chemosensitivity of malignant melanoma tumors via proteasome inhibition: implication for bortezomib (VELCADE, PS-341) as a therapeutic agent for malignant melanoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of nuclear factor-kappa B in melanoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Critical upstream signals of cytochrome C release induced by a novel Bcl-2 inhibitor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Integrin-mediated adhesion regulates ERK nuclear translocation and phosphorylation of Elk-1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Synthetic Smac/DIABLO peptides enhance the effects of chemotherapeutic agents by binding XIAP and cIAP1 in situ
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Targeting death and decoy receptors of the tumour-necrosis factor superfamily
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Proteolytic activation of protein kinase C-epsilon by caspase-mediated processing and transduction of antiapoptotic signals
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phase II evaluation of bryostatin-1 in metastatic melanoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Spontaneous and drug-induced apoptosis is mediated by conformational changes of Bax and Bak in B-cell chronic lymphocytic leukemia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ranking the role of RANK ligand in apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Targeting the JNK MAPK cascade for inhibition: basic science and therapeutic potential.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cancer cell death by programmed necrosis?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ten years of protein kinase B signalling: a hard Akt to follow
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
JNK is associated with Bcl-2 and PP1 in mitochondria: paclitaxel induces its activation and its association with the phosphorylated form of Bcl-2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apoptosis genes and resistance to cancer therapy: what does the experimental and clinical data tell us?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Imidazole carboxamide therapy in advanced malignant melanoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
PUMA couples the nuclear and cytoplasmic proapoptotic function of p53
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
G1/S cell cycle arrest provides anoikis resistance through Erk-mediated Bim suppression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Bcl2 family: regulators of the cellular life-or-death switch
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The molecular control of DNA damage-induced cell death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Prognostic significance of activated Akt expression in melanoma: a clinicopathologic study of 292 cases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutations of the BRAF gene in human cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Treatment of melanoma cells with a bcl-2/bcl-xL antisense oligonucleotide induces antiangiogenic activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TRAIL-induced apoptosis requires Bax-dependent mitochondrial release of Smac/DIABLO.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Prospects: histone deacetylase inhibitors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Heat shock protein 90 indirectly regulates ERK activity by affecting Raf protein metabolism
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential regulation of noxa in normal melanocytes and melanoma cells by proteasome inhibition: therapeutic implications.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Involvement of protein kinase C delta (PKCdelta) in phorbol ester-induced apoptosis in LNCaP prostate cancer cells. Lack of proteolytic cleavage of PKCdelta
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Smac agonists sensitize for Apo2L/TRAIL- or anticancer drug-induced apoptosis and induce regression of malignant glioma in vivo.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Essential roles of the Bcl-2 family of proteins in caspase-2-induced apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Variable expression of protein kinase C epsilon in human melanoma cells regulates sensitivity to TRAIL-induced apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Protein kinase C regulates FADD recruitment and death-inducing signaling complex formation in Fas/CD95-induced apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Malignant transformation of melanocytes to melanoma by constitutive activation of mitogen-activated protein kinase kinase (MAPKK) signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A matter of life and death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ectopic overexpression of second mitochondria-derived activator of caspases (Smac/DIABLO) or cotreatment with N-terminus of Smac/DIABLO peptide potentiates epothilone B derivative-(BMS 247550) and Apo-2L/TRAIL-induced apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Protein kinase C modulates tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by targeting the apical events of death receptor signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bcl-XL is a chemoresistance factor in human melanoma cells that can be inhibited by antisense therapy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
JNK/SAPK activity contributes to TRAIL-induced apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
How melanoma cells evade trail-induced apoptosis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apoptosis and drug response
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
bcl-2 antisense therapy chemosensitizes human melanoma in SCID mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Chemosensitisation of malignant melanoma by BCL2 antisense therapy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Deficient tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) death receptor transport to the cell surface in human colon cancer cells selected for resistance to TRAIL-induced apoptosis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bcl-2 acts in a proangiogenic signaling pathway through nuclear factor-kappaB and CXC chemokines.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Oblimersen Bcl-2 antisense: facilitating apoptosis in anticancer treatment
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mitochondrial p53 activates Bak and causes disruption of a Bak-Mcl1 complex.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Extracellular signal-regulated kinases 1/2 are serum-stimulated "Bim(EL) kinases" that bind to the BH3-only protein Bim(EL) causing its phosphorylation and turnover
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulatory phosphorylation of Bim: sorting out the ERK from the JNK
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of a DEF-type docking domain for extracellular signal-regulated kinases 1/2 that directs phosphorylation and turnover of the BH3-only protein BimEL.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Protein kinase Cdelta targets mitochondria, alters mitochondrial membrane potential, and induces apoptosis in normal and neoplastic keratinocytes when overexpressed by an adenoviral vector
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Induction of autophagy and inhibition of tumorigenesis by beclin 1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
RACK1 mediates activation of JNK by protein kinase C [corrected].
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phase I and pharmacodynamic study of the oral MEK inhibitor CI-1040 in patients with advanced malignancies
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Growth factor regulation of autophagy and cell survival in the absence of apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mitochondrial translocation of protein kinase C delta in phorbol ester-induced cytochrome c release and apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CCI-779 in metastatic melanoma: a phase II trial of the California Cancer Consortium
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Perspective: the chemotherapeutic relevance of apoptosis and a proposed biochemical cascade for chemotherapeutically induced apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
G1 cell-cycle control and cancer
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of PKCalpha induces a PKCdelta-dependent apoptotic program in salivary epithelial cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bcl2 regulation by the melanocyte master regulator Mitf modulates lineage survival and melanoma cell viability
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phorbol 12-myristate 13-acetate inhibits death receptor-mediated apoptosis in Jurkat cells by disrupting recruitment of Fas-associated polypeptide with death domain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
BRAFE600-associated senescence-like cell cycle arrest of human naevi
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transcription-independent pro-apoptotic functions of p53.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Selective activation of the c-Jun N-terminal kinase (JNK) pathway fails to elicit Bax activation or apoptosis unless the phosphoinositide 3'-kinase (PI3K) pathway is inhibited
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The tumor necrosis factor-related apoptosis-inducing ligand receptors TRAIL-R1 and TRAIL-R2 have distinct cross-linking requirements for initiation of apoptosis and are non-redundant in JNK activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Protein kinase C: structure, function, and regulation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pathways of apoptotic and non-apoptotic death in tumour cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
(-)-Gossypol acts directly on the mitochondria to overcome Bcl-2- and Bcl-X(L)-mediated apoptosis resistance
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An inhibitor of Bcl-2 family proteins induces regression of solid tumours
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Colorectal cancer: mutations in a signalling pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Microarray expression profiling in melanoma reveals a BRAF mutation signature.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
PTEN inactivation is rare in melanoma tumours but occurs frequently in melanoma cell lines
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
High frequency of BRAF mutations in nevi
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of human tumor cell growth in vivo by an orally bioavailable inhibitor of human farnesyltransferase, BIM-46228.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bmf: a proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Keeping killers on a tight leash: transcriptional and post-translational control of the pro-apoptotic activity of BH3-only proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Functional and therapeutic significance of Akt deregulation in malignant melanoma.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Rapamycin inhibits doxorubicin-induced NF-kappaB/Rel nuclear activity and enhances the apoptosis of melanoma cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of protein kinase C inhibits TRAIL-induced caspases activation, mitochondrial events and apoptosis in a human leukemic T cell line
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Stimulation of the mitogen-activated protein kinase pathway antagonizes TRAIL-induced apoptosis downstream of BID cleavage in human breast cancer MCF-7 cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibitor of apoptosis proteins: translating basic knowledge into clinical practice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Small-molecule antagonists of apoptosis suppressor XIAP exhibit broad antitumor activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caspase-2 primes cancer cells for TRAIL-mediated apoptosis by processing procaspase-8
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A protective role of PKCepsilon against TNF-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in glioma cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tunicamycin enhances tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in human prostate cancer cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Curcumin-induced antiproliferative and proapoptotic effects in melanoma cells are associated with suppression of IkappaB kinase and nuclear factor kappaB activity and are independent of the B-Raf/mitogen-activated/extracellular signal-regulated prot
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A pivotal role for ERK in the oncogenic behaviour of malignant melanoma?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Farnesyl transferase inhibitor SCH66336 is cytostatic, pro-apoptotic and enhances chemosensitivity to cisplatin in melanoma cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Comparison of 17-dimethylaminoethylamino-17-demethoxy-geldanamycin (17DMAG) and 17-allylamino-17-demethoxygeldanamycin (17AAG) in vitro: effects on Hsp90 and client proteins in melanoma models
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
BRAF mutation predicts sensitivity to MEK inhibition
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phase I clinical and pharmacokinetic study of the Novel Raf kinase and vascular endothelial growth factor receptor inhibitor BAY 43-9006 in patients with advanced refractory solid tumors.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Initiation of apoptosis by granzyme B requires direct cleavage of bid, but not direct granzyme B-mediated caspase activation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Protein kinase C inhibitors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A small molecule compound inhibits AKT pathway in ovarian cancer cell lines.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mcl-1 antisense therapy chemosensitizes human melanoma in a SCID mouse xenotransplantation model
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mcl-1 is a novel therapeutic target for human sarcoma: synergistic inhibition of human sarcoma xenotransplants by a combination of mcl-1 antisense oligonucleotides with low-dose cyclophosphamide
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The PIDDosome, a protein complex implicated in activation of caspase-2 in response to genotoxic stress
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of MCL1 through a serum response factor/Elk-1-mediated mechanism links expression of a viability-promoting member of the BCL2 family to the induction of hematopoietic cell differentiation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A randomized phase II study of two schedules of bryostatin-1 (NSC339555) in patients with advanced malignant melanoma: A National Cancer Institute of Canada Clinical Trials Group study
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CTL granules: evolution of vesicles essential for combating virus infections
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Granzyme B: pro-apoptotic, antiviral and antitumor functions
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Management of cutaneous melanoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
JNK promotes Bax translocation to mitochondria through phosphorylation of 14-3-3 proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tbx2 is overexpressed and plays an important role in maintaining proliferation and suppression of senescence in melanomas
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular determinants of kinase pathway activation by Apo2 ligand/tumor necrosis factor-related apoptosis-inducing ligand
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
IAPs, RINGs and ubiquitylation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibitor of apoptosis proteins and their relatives: IAPs and other BIRPs
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Small interfering RNA targeting bcl-2 sensitizes malignant melanoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of apoptosis in vivo by a hydrocarbon-stapled BH3 helix
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Elevated expression of MITF counteracts B-RAF-stimulated melanocyte and melanoma cell proliferation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Loss of protein kinase C function induces an apoptotic response
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Life in the balance: how BH3-only proteins induce apoptosis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Induction of beta3-integrin gene expression by sustained activation of the Ras-regulated Raf-MEK-extracellular signal-regulated kinase signaling pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structural basis of IAP recognition by Smac/DIABLO
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Addicted to death: invasive cancer and the immune response to unscheduled cell death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of BAX in the apoptotic response to anticancer agents
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of ERK1/2 protects melanoma cells from TRAIL-induced apoptosis by inhibiting Smac/DIABLO release from mitochondria
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human melanoma cells selected for resistance to apoptosis by prolonged exposure to tumor necrosis factor-related apoptosis-inducing ligand are more vulnerable to necrotic cell death induced by cisplatin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Translational control of tumor necrosis factor-related apoptosis-inducing ligand death receptor expression in melanoma cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Death by design: the big debut of small molecules.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caspase-2 function in response to DNA damage
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of the extracellular signal regulated kinase (ERK) pathway in human melanoma.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Alkylating DNA damage stimulates a regulated form of necrotic cell death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0074-7696%2806%2951004-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0074-7696(06)51004-6
1 reference
stated in
Europe PubMed Central
PubMed publication ID
16939779
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16939779%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 December 2019
PubMed publication ID
16939779
1 reference
stated in
Europe PubMed Central
PubMed publication ID
16939779
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16939779%20AND%20SRC:MED&resulttype=core&format=json
retrieved
29 December 2019
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit