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MNK1 and EIF4E are downstream effectors of MEKs in the regulation of the nuclear export of HDM2 mRNA.
scientific article published on 10 September 2007
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17828301
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17828301%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 January 2020
title
MNK1 and EIF4E are downstream effectors of MEKs in the regulation of the nuclear export of HDM2 mRNA
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17828301
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17828301%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 January 2020
author
Jeremy P Blaydes
series ordinal
2
1 reference
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Europe PubMed Central
PubMed publication ID
17828301
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17828301%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 January 2020
author name string
A Phillips
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17828301
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17828301%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 January 2020
language of work or name
English
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publication date
10 September 2007
1 reference
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Europe PubMed Central
PubMed publication ID
17828301
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17828301%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 January 2020
published in
Oncogene
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Europe PubMed Central
PubMed publication ID
17828301
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17828301%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 January 2020
volume
27
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17828301
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17828301%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 January 2020
issue
11
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17828301
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17828301%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 January 2020
page(s)
1645-1649
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17828301
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17828301%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 January 2020
cites work
Mapping of the p53 and mdm-2 interaction domains
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210785
retrieved
21 January 2018
Controlling gene expression through RNA regulons: the role of the eukaryotic translation initiation factor eIF4E.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210785
retrieved
21 January 2018
Tolerance of high levels of wild-type p53 in transformed epithelial cells dependent on auto-regulation by mdm-2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210785
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The proliferation of normal human fibroblasts is dependent upon negative regulation of p53 function by mdm2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210785
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A single nucleotide polymorphism in the MDM2 promoter attenuates the p53 tumor suppressor pathway and accelerates tumor formation in humans
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210785
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7 January 2021
based on heuristic
inferred from DOI database lookup
A single nucleotide polymorphism in the p53 pathway interacts with gender, environmental stresses and tumor genetics to influence cancer in humans
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210785
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53 ubiquitination: Mdm2 and beyond
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210785
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Mnks are novel components in the control of TNF alpha biosynthesis and phosphorylate and regulate hnRNP A1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210785
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
eIF4E promotes nuclear export of cyclin D1 mRNAs via an element in the 3'UTR
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210785
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
eIF4E is a central node of an RNA regulon that governs cellular proliferation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210785
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nuclear RNA export
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210785
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nuclear export of mRNA: from the site of transcription to the cytoplasm
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210785
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Delineation of mRNA export pathways by the use of cell-permeable peptides
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210785
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Organizing mRNA export
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210785
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Negative regulation of protein translation by mitogen-activated protein kinase-interacting kinases 1 and 2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210785
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Epigenetic activation of a subset of mRNAs by eIF4E explains its effects on cell proliferation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210785
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
eIF4E--from translation to transformation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210785
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Amplification of a gene encoding a p53-associated protein in human sarcomas
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210785
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MEK-ERK signaling controls Hdm2 oncoprotein expression by regulating hdm2 mRNA export to the cytoplasm.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210785
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
GC-selective DNA-binding antibiotic, mithramycin A, reveals multiple points of control in the regulation of Hdm2 protein synthesis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210785
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The mechanisms of regulation of Hdm2 protein level by serum growth factors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210785
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Opposing effects of Ras on p53: transcriptional activation of mdm2 and induction of p19ARF.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210785
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Translation initiation of ornithine decarboxylase and nucleocytoplasmic transport of cyclin D1 mRNA are increased in cells overexpressing eukaryotic initiation factor 4E.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210785
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Induction of Mdm2 and enhancement of cell survival by bFGF.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210785
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Aberrant eukaryotic translation initiation factor 4E-dependent mRNA transport impedes hematopoietic differentiation and contributes to leukemogenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210785
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphorylation of the eukaryotic translation initiation factor eIF4E contributes to its transformation and mRNA transport activities
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210785
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
In vivo activation of the p53 pathway by small-molecule antagonists of MDM2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210785
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Surfing the p53 network
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210785
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The mRNA cap-binding protein eIF4E in post-transcriptional gene expression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210785
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The evolution of diverse biological responses to DNA damage: insights from yeast and p53.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210785
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dual-site regulation of MDM2 E3-ubiquitin ligase activity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210785
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mitogen-activated protein kinases activate the serine/threonine kinases Mnk1 and Mnk2
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210785
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A functional p53-responsive intronic promoter is contained within the human mdm2 gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FSJ.ONC.1210785
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/SJ.ONC.1210785
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17828301
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17828301%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 January 2020
Dimensions Publication ID
1020132052
0 references
PubMed publication ID
17828301
1 reference
stated in
Europe PubMed Central
PubMed publication ID
17828301
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17828301%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 January 2020
ResearchGate publication ID
6012874
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