(Q38956617)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25220458%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

title

κB-Ras proteins regulate both NF-κB-dependent inflammation and Ral-dependent proliferation (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25220458%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

0 references

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25220458%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Yenkel Grinberg-Bleyer

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25220458%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Christian Gruber

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25220458%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

author name string

Andrea Oeckinghaus

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25220458%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Ping Rao

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25220458%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Heike Schmitt

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25220458%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Verena Schmitt

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25220458%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Lars I Kühn

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25220458%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Gustav E Lienhard

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25220458%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

Sankar Ghosh

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25220458%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

language of work or name

1 reference

15 September 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25220458%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25220458%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

volume

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25220458%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

issue

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25220458%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

page(s)

1793-1807

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25220458%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

16 February 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4177457/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Negative regulation of the RalGAP complex by 14-3-3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177457

Regulation of small GTPases by GEFs, GAPs, and GDIs

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177457

Genetic deletion of RALA and RALB small GTPases reveals redundant functions in development and tumorigenesis

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177457

Transcriptional signatures of Ral GTPase are associated with aggressive clinicopathologic characteristics in human cancer

9 September 2017

1 reference

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Rnd1 and Rnd3 targeting to lipid raft is required for p190 RhoGAP activation

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177457

NF-κB, the first quarter-century: remarkable progress and outstanding questions

9 September 2017

1 reference

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A protein complex network of Drosophila melanogaster

9 September 2017

1 reference

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Inflammation meets cancer, with NF-κB as the matchmaker

9 September 2017

1 reference

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Ras history: The saga continues

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177457

Activation and involvement of Ral GTPases in colorectal cancer

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177457

Prognostic biomarkers for esophageal adenocarcinoma identified by analysis of tumor transcriptome

9 September 2017

1 reference

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A Ral GAP complex links PI 3-kinase/Akt signaling to RalA activation in insulin action

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177457

Proteomic identification of salivary transferrin as a biomarker for early detection of oral cancer

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177457

Aberrant overexpression of the Rgl2 Ral small GTPase-specific guanine nucleotide exchange factor promotes pancreatic cancer growth through Ral-dependent and Ral-independent mechanisms

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177457

IkappaBbeta acts to inhibit and activate gene expression during the inflammatory response

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177457

KappaB-Ras is a nuclear-cytoplasmic small GTPase that inhibits NF-kappaB activation through the suppression of transcriptional activation of p65/RelA

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177457

Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1

9 September 2017

1 reference

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Requirement for NF-kappaB signalling in a mouse model of lung adenocarcinoma

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177457

Ras signaling and therapies

9 September 2017

1 reference

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Tuberous sclerosis tumor suppressor complex-like complexes act as GTPase-activating proteins for Ral GTPases

9 September 2017

1 reference

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Truncation of the catalytic domain of the cylindromatosis tumor suppressor impairs lung maturation

9 September 2017

1 reference

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Ras oncogenes: split personalities

9 September 2017

1 reference

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9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177457

Stromal gene expression predicts clinical outcome in breast cancer

9 September 2017

1 reference

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Shared principles in NF-kappaB signaling

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177457

Ral GTPases and cancer: linchpin support of the tumorigenic platform

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177457

Mesenchymal stem cells within tumour stroma promote breast cancer metastasis

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177457

Expression of ral GTPases, their effectors, and activators in human bladder cancer

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177457

GEFs and GAPs: critical elements in the control of small G proteins

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177457

Divergent roles for RalA and RalB in malignant growth of human pancreatic carcinoma cells.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177457

RalB GTPase-mediated activation of the IkappaB family kinase TBK1 couples innate immune signaling to tumor cell survival

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177457

Nuclear factor-kappaB in cancer development and progression

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177457

Adipocytes contain a novel complex similar to the tuberous sclerosis complex

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177457

The metastasis-associated gene CD24 is regulated by Ral GTPase and is a mediator of cell proliferation and survival in human cancer

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177457

The Ras superfamily at a glance

9 September 2017

1 reference

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Human RAS superfamily proteins and related GTPases

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177457

Inhibition of NF-kappaB activity by IkappaBbeta in association with kappaB-Ras

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177457

Quantitative studies of the growth of mouse embryo cells in culture and their development into established lines

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177457

Ral-GTPases: approaching their 15 minutes of fame

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177457

RAL GTPases are linchpin modulators of human tumour-cell proliferation and survival

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177457

Rnd proteins function as RhoA antagonists by activating p190 RhoGAP

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177457

KappaB-Ras binds to the unique insert within the ankyrin repeat domain of IkappaBbeta and regulates cytoplasmic retention of IkappaBbeta x NF-kappaB complexes

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177457

The IkappaB-NF-kappaB signaling module: temporal control and selective gene activation

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177457

Distinct requirements for Ras oncogenesis in human versus mouse cells

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177457

Pulmonary surfactant: functions, abnormalities and therapeutic options

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177457

Diversity of gene expression in adenocarcinoma of the lung

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177457

Function of surfactant proteins B and C

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177457

RalGEF2, a pleckstrin homology domain containing guanine nucleotide exchange factor for Ral

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177457

A novel RalGEF-like protein, RGL3, as a candidate effector for rit and Ras

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177457

Identification and characterization of a new family of guanine nucleotide exchange factors for the ras-related GTPase Ral

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177457

A subclass of Ras proteins that regulate the degradation of IkappaB

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177457

Ras caught in another affair: the exchange factors for Ral.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177457

Ral-GTPases mediate a distinct downstream signaling pathway from Ras that facilitates cellular transformation

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177457

Tumor necrosis factor-alpha inhibits expression of pulmonary surfactant protein

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177457

Downregulation of Ral GTPase-activating protein promotes tumor invasion and metastasis of bladder cancer

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177457

Ral overactivation in malignant peripheral nerve sheath tumors

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177457

Activation of RalA is critical for Ras-induced tumorigenesis of human cells.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177457

Distinct functional properties of IkappaB alpha and IkappaB beta

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177457

IkappaB family members function by different mechanisms

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177457

Tumor Necrosis Factor-α Inhibits Surfactant Protein C Gene Transcription

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177457

IkappaBbeta is an essential co-activator for LPS-induced IL-1beta transcription in vivo.

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177457

A role for the Ral guanine nucleotide dissociation stimulator in mediating Ras-induced transformation

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177457

Prognostic significance of kappaB-Ras1 expression in gliomas.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177457

Genetic and epigenetic changes of NKIRAS1 gene in human renal cell carcinomas

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177457

Neuronal and glioma-derived stem cell factor induces angiogenesis within the brain

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177457

Enhanced cathepsin L expression is mediated by different Ras effector pathways in fibroblasts and epithelial cells

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4177457

Tumor necrosis factor-alpha decreases surfactant protein B mRNA in murine lung

21 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25220458

12 December 2020

inferred from PubMed ID database lookup

Species- and cell type-specific requirements for cellular transformation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25220458

12 December 2020

inferred from PubMed ID database lookup

I kappa B-beta regulates the persistent response in a biphasic activation of NF-kappa B

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25220458

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1016/J.CELREP.2014.08.015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25220458%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25220458%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

PubMed publication ID

25220458

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25220458%20AND%20SRC:MED&resulttype=core&format=json