(Q38962343)

English

Coagulation and angiogenic gene expression profiles are defined by molecular subgroups of medulloblastoma: evidence for growth factor-thrombin cross-talk

scientific article published on 26 September 2014

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scholarly article

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Europe PubMed Central

PubMed publication ID

8 September 2017

Coagulation and angiogenic gene expression profiles are defined by molecular subgroups of medulloblastoma: evidence for growth factor-thrombin cross-talk (English)

1 reference

Europe PubMed Central

PubMed publication ID

8 September 2017

medulloblastoma

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Stefan M. Pfister

3

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25163932%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

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M Kool

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6 June 2020

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J Rak

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6 June 2020

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E D'Asti

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6 June 2020

publication date

26 September 2014

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8 September 2017

Journal of Thrombosis and Haemostasis

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25163932%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

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6 June 2020

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6 June 2020

1838-1849

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6 June 2020

Vaso-occlusive and prothrombotic mechanisms associated with tumor hypoxia, necrosis, and accelerated growth in glioblastoma

1 reference

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21 January 2018

Epidemiology of venous thromboembolism in 9489 patients with malignant glioma.

1 reference

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Cancer and coagulation

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Role of tissue factor in hemostasis, thrombosis, and vascular development

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21 January 2018

Tissue factor and cell signalling in cancer progression and thrombosis

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Tumors: wounds that do not heal. Similarities between tumor stroma generation and wound healing

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Role of tissue factor in cancer

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21 January 2018

Tissue factor- and factor X-dependent activation of protease-activated receptor 2 by factor VIIa

1 reference

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21 January 2018

The endothelial protein C receptor supports tissue factor ternary coagulation initiation complex signaling through protease-activated receptors.

1 reference

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21 January 2018

PTEN and hypoxia regulate tissue factor expression and plasma coagulation by glioblastoma.

1 reference

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21 January 2018

Tissue factor regulation by epidermal growth factor receptor and epithelial-to-mesenchymal transitions: effect on tumor initiation and angiogenesis

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Oncogenic epidermal growth factor receptor up-regulates multiple elements of the tissue factor signaling pathway in human glioma cells.

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c-Met activation in medulloblastoma induces tissue factor expression and activity: effects on cell migration.

1 reference

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21 January 2018

Tissue factor mediates the HGF/Met-induced anti-apoptotic pathway in DAOY medulloblastoma cells.

1 reference

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21 January 2018

Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1

1 reference

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21 January 2018

Medulloblastoma comprises four distinct molecular variants

1 reference

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21 January 2018

Markers of survival and metastatic potential in childhood CNS primitive neuro-ectodermal brain tumours: an integrative genomic analysis

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21 January 2018

Coagulation-related gene expression profile in glioblastoma is defined by molecular disease subtype

1 reference

https://api.crossref.org/works/10.1111%2FJTH.12715

21 January 2018

Medulloblastoma molecular dissection: the way toward targeted therapy

1 reference

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21 January 2018

Hepatocyte growth factor and sonic Hedgehog expression in cerebellar neural progenitor cells costimulate medulloblastoma initiation and growth

1 reference

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21 January 2018

Molecular subgroups of medulloblastoma: an international meta-analysis of transcriptome, genetic aberrations, and clinical data of WNT, SHH, Group 3, and Group 4 medulloblastomas

1 reference

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21 January 2018

Molecular subgroups of medulloblastoma: the current consensus

1 reference

https://api.crossref.org/works/10.1111%2FJTH.12715

21 January 2018

Integrative genomic analysis of medulloblastoma identifies a molecular subgroup that drives poor clinical outcome

1 reference

https://api.crossref.org/works/10.1111%2FJTH.12715

21 January 2018

Medulloblastoma: clinicopathological correlates of SHH, WNT, and non-SHH/WNT molecular subgroups

1 reference

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21 January 2018

Definition of disease-risk stratification groups in childhood medulloblastoma using combined clinical, pathologic, and molecular variables

1 reference

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21 January 2018

Outcome prediction in pediatric medulloblastoma based on DNA copy-number aberrations of chromosomes 6q and 17q and the MYC and MYCN loci

1 reference

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21 January 2018

Low-level copy number changes of MYC genes have a prognostic impact in medulloblastoma.

1 reference

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21 January 2018

Biological and clinical heterogeneity of MYCN-amplified medulloblastoma.

1 reference

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21 January 2018

The scatter factor/hepatocyte growth factor: c-met pathway in human embryonal central nervous system tumor malignancy

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21 January 2018

Drug development of MET inhibitors: targeting oncogene addiction and expedience

1 reference

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21 January 2018

Sonic hedgehog regulates Bmi1 in human medulloblastoma brain tumor-initiating cells.

1 reference

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21 January 2018

Integrated genomics identifies five medulloblastoma subtypes with distinct genetic profiles, pathway signatures and clinicopathological features

1 reference

https://api.crossref.org/works/10.1111%2FJTH.12715

21 January 2018

Novel mutations target distinct subgroups of medulloblastoma.

1 reference

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21 January 2018

Beta-catenin status in paediatric medulloblastomas: correlation of immunohistochemical expression with mutational status, genetic profiles, and clinical characteristics

1 reference

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21 January 2018

Gene expression analyses reveal molecular relationships among 20 regions of the human CNS.

1 reference

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21 January 2018

Pediatric rhabdoid tumors of kidney and brain show many differences in gene expression but share dysregulation of cell cycle and epigenetic effector genes

1 reference

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21 January 2018

Insulin-like growth factor II is involved in the proliferation control of medulloblastoma and its cerebellar precursor cells

1 reference

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21 January 2018

Growth-regulated oncogene is pivotal in thrombin-induced angiogenesis

1 reference

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21 January 2018

Selection of reference genes in mouse embryos and in differentiating human and mouse ES cells.

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21 January 2018

Genetic and molecular mechanisms of age regulation (homeostasis) of blood coagulation

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21 January 2018

Transcriptional program induced by factor VIIa-tissue factor, PAR1 and PAR2 in MDA-MB-231 cells

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21 January 2018

Adult and pediatric medulloblastomas are genetically distinct and require different algorithms for molecular risk stratification

1 reference

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21 January 2018

Thrombin enhances monocyte secretion of tumor necrosis factor and interleukin-1 beta by two distinct mechanisms

1 reference

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21 January 2018

Thrombin modulates the expression of a set of genes including thrombospondin-1 in human microvascular endothelial cells.

1 reference

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21 January 2018

Dendritic cell PAR1-S1P3 signalling couples coagulation and inflammation

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21 January 2018

Thrombin induces tumor invasion through the induction and association of matrix metalloproteinase-9 and beta1-integrin on the cell surface

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Identification of chondromodulin I as a novel endothelial cell growth inhibitor. Purification and its localization in the avascular zone of epiphyseal cartilage

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Characterization and gene expression profiling of five new human embryonic stem cell lines derived in Taiwan

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Chondromodulin-1 directly suppresses growth of human cancer cells

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Epidemiology and clinical risk factors predisposing to thromboembolism in children with cancer.

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Thrombin generation and the pathogenesis of cancer

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Kinetic analysis of a unique direct prothrombinase, fgl2, and identification of a serine residue critical for the prothrombinase activity

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Downregulation of FGL2/prothrombinase delays HCCLM6 xenograft tumour growth and decreases tumour angiogenesis

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Effects of micro-environment- and malignant cell-derived interleukin-1 in carcinogenesis, tumour invasiveness and tumour-host interactions

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IL-1 is required for tumor invasiveness and angiogenesis

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Molecular mechanisms and clinical applications of angiogenesis

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The role of IL-1β in the early tumor cell-induced angiogenic response.

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Identifiers

10.1111/JTH.12715

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25163932%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25163932%20AND%20SRC:MED&resulttype=core&format=json

6 June 2020

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