(Q38971068)

8 September 2017

title

Generating thermostabilized agonist-bound GPR40/FFAR1 using virus-like particles and a label-free binding assay (English)

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8 September 2017

Yoshihiko Hirozane

1

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8 September 2017

Takashi Motoyaji

2

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8 September 2017

Takamitsu Maru

3

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8 September 2017

Kengo Okada

4

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8 September 2017

Naoki Tarui

5

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8 September 2017

language of work or name

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1 August 2014

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Molecular Membrane Biology

8 September 2017

published in

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8 September 2017

volume

31

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8 September 2017

issue

5

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8 September 2017

page(s)

168-175

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GPR40-induced insulin secretion by the novel agonist TAK-875: first clinical findings in patients with type 2 diabetes

8 September 2017

cites work

1 reference

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Discovery of 1,2,4-Triazine Derivatives as Adenosine A 2A Antagonists using Structure Based Drug Design

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Free fatty acids regulate insulin secretion from pancreatic beta cells through GPR40.

21 January 2018

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Thermostabilisation of an agonist-bound conformation of the human adenosine A(2A) receptor

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A multiple-ascending-dose study to evaluate safety, pharmacokinetics, and pharmacodynamics of a novel GPR40 agonist, TAK-875, in subjects with type 2 diabetes

21 January 2018

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TAK-875, an orally available G protein-coupled receptor 40/free fatty acid receptor 1 agonist, enhances glucose-dependent insulin secretion and improves both postprandial and fasting hyperglycemia in type 2 diabetic rats

21 January 2018

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21 January 2018

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A novel antidiabetic drug, fasiglifam/TAK-875, acts as an ago-allosteric modulator of FFAR1

21 January 2018

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21 January 2018

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In-fusion assembly: seamless engineering of multidomain fusion proteins, modular vectors, and mutations.

21 January 2018

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Increased expression and immunogenicity of sequence-modified human immunodeficiency virus type 1 gag gene

21 January 2018

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10.3109/09687688.2014.923588

21 January 2018

Identifiers

DOI

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8 September 2017

1 reference