(Q38973682)

8 September 2017

title

The Gβ5 protein regulates sensitivity to TRAIL-induced cell death in colon carcinoma (English)

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8 September 2017

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D Fuchs

1

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8 September 2017

M Metzig

2

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8 September 2017

M Bickeböller

3

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8 September 2017

C Brandel

4

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8 September 2017

W Roth

5

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8 September 2017

language of work or name

English

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publication date

21 July 2014

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8 September 2017

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8 September 2017

volume

34

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8 September 2017

issue

21

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8 September 2017

page(s)

2753-2763

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https://scigraph.springernature.com/pub.10.1038/onc.2014.213

8 September 2017

exact match

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cites work

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Isozyme-selective stimulation of phospholipase C-beta 2 by G protein beta gamma-subunits

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Type-specific regulation of adenylyl cyclase by G protein beta gamma subunits

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Voltage-dependent modulation of N-type calcium channels by G-protein beta gamma subunits

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Crosstalk between G proteins and protein kinase C mediated by the calcium channel alpha1 subunit.

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Knockout of G protein β5 impairs brain development and causes multiple neurologic abnormalities in mice

21 January 2018

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Gbeta5 is required for normal light responses and morphology of retinal ON-bipolar cells.

21 January 2018

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Immunohistochemical Localization of G Protein β1, β2, β3, β4, β5, and γ3 Subunits in the Adult Rat Brain

21 January 2018

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Nuclear localization of G protein beta 5 and regulator of G protein signaling 7 in neurons and brain

21 January 2018

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Identification of overexpression of orphan G protein-coupled receptor GPR49 in human colon and ovarian primary tumors

21 January 2018

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Molecular targeting of Gα and Gβγ subunits: a potential approach for cancer therapeutics

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Differential targeting of Gbetagamma-subunit signaling with small molecules

21 January 2018

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Small molecule disruption of G protein beta gamma subunit signaling inhibits neutrophil chemotaxis and inflammation

21 January 2018

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X-linked inhibitor of apoptosis protein (XIAP) is a nonredundant modulator of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis in human cancer cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2014.213

XIAP as a ubiquitin ligase in cellular signaling

21 January 2018

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Regulating TRAIL receptor-induced cell death at the membrane : a deadly discussion

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2014.213

Importin β1 protein-mediated nuclear localization of death receptor 5 (DR5) limits DR5/tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL)-induced cell death of human tumor cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2014.213

The Wnt connection to tumorigenesis

21 January 2018

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A ride on the ferrous wheel.

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2014.213

The expanding roles of Gβγ subunits in G protein-coupled receptor signaling and drug action

21 January 2018

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Palmitoylation regulates plasma membrane-nuclear shuttling of R7BP, a novel membrane anchor for the RGS7 family

21 January 2018

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Structure, function, and localization of Gβ5-RGS complexes

21 January 2018

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Regulators of G protein signaling (RGS) proteins as drug targets: modulating G-protein-coupled receptor (GPCR) signal transduction

21 January 2018

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Constitutive nuclear factor-kappaB-RelA activation is required for proliferation and survival of Hodgkin's disease tumor cells

21 January 2018

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Constitutive activation of NF-kappaB and T-cell leukemia/lymphoma in Notch3 transgenic mice

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2014.213

High constitutive level of NF-kappaB is crucial for viability of adenocarcinoma cells

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2014.213

Targeting NF-kappaB for colorectal cancer

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2014.213

Ggamma subunit-selective G protein beta 5 mutant defines regulators of G protein signaling protein binding requirement for nuclear localization

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2014.213

Inhibition of JNK activation through NF-kappaB target genes

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2014.213

Activation of NF-kappa B by XIAP, the X chromosome-linked inhibitor of apoptosis, in endothelial cells involves TAK1

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2014.213

XIAP Induces NF-κB Activation via the BIR1/TAB1 Interaction and BIR1 Dimerization

21 January 2018

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A novel role for XIAP in copper homeostasis through regulation of MURR1

21 January 2018

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Akt phosphorylation and stabilization of X-linked inhibitor of apoptosis protein (XIAP).

21 January 2018

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AKT controls human first trimester trophoblast cell sensitivity to FAS-mediated apoptosis by regulating XIAP expression

21 January 2018

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Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) contributes to interferon gamma-dependent natural killer cell protection from tumor metastasis

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2014.213

Critical role for tumor necrosis factor-related apoptosis-inducing ligand in immune surveillance against tumor development

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2014.213

TRAIL resistance of breast cancer cells is associated with constitutive endocytosis of death receptors 4 and 5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.213

Nucleocytoplasmic transport of proteins

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2014.213

Nuclear transport and cancer: from mechanism to intervention

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2014.213

Nuclear localization in the biology of the CD40 receptor in normal and neoplastic human B lymphocytes.

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2014.213

Nuclear and cytoplasmic death receptor 5 as prognostic factors in patients with non-small cell lung cancer treated with chemotherapy

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2014.213

Identification of a small molecule inhibitor of importin β mediated nuclear import by confocal on-bead screening of tagged one-bead one-compound libraries.

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2014.213

TRAIL induced survival and proliferation in cancer cells resistant towards TRAIL-induced apoptosis mediated by NF-kappaB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.213

Constitutively activated nuclear factor-kappaB, but not induced NF-kappaB, leads to TRAIL resistance by up-regulation of X-linked inhibitor of apoptosis protein in human cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.213

Rottlerin sensitizes glioma cells to TRAIL-induced apoptosis by inhibition of Cdc2 and the subsequent downregulation of survivin and XIAP.

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2014.213

Loss of XIAP protein expression by RNAi and antisense approaches sensitizes cancer cells to functionally diverse chemotherapeutics

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2014.213

Potent antileukemic interactions between flavopiridol and TRAIL/Apo2L involve flavopiridol-mediated XIAP downregulation

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2014.213

A Phase II trial of suramin monthly x 3 for hormone-refractory prostate carcinoma

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2014.213

Targeting Gbetagamma signaling to inhibit prostate tumor formation and growth

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2014.213

Small molecule disruption of G beta gamma signaling inhibits the progression of heart failure

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2014.213

Phase I/II trial of AEG35156 X-linked inhibitor of apoptosis protein antisense oligonucleotide combined with idarubicin and cytarabine in patients with relapsed or primary refractory acute myeloid leukemia

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2014.213

Crosstalk between G-protein-coupled receptors and epidermal growth factor receptor in cancer

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2014.213

Colorectal cancer in review: the role of the EGFR pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.213

Critical update and emerging trends in epidermal growth factor receptor targeting in cancer

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2014.213

Current status of cetuximab for the treatment of patients with solid tumors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.213

Notch1 signaling promotes survival of glioblastoma cells via EGFR-mediated induction of anti-apoptotic Mcl-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.213

β-Catenin activates the growth factor endothelin-1 in colon cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.213

Environmental-dependent acceleration of a developmental switch: the floral transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.213

Prolonged photoresponses and defective adaptation in rods of Gbeta5-/- mice.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.213

Differential modulation of adenylyl cyclases I and II by various G beta subunits

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.213

NF-kappaB promotes breast cancer cell migration and metastasis by inducing the expression of the chemokine receptor CXCR4

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.213

Activation of NF-kappa B by bradykinin through a Galpha(q)- and Gbeta gamma-dependent pathway that involves phosphoinositide 3-kinase and Akt

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.213

Rel/NF-kappaB transcription factors protect against tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL)-induced apoptosis by up-regulating the TRAIL decoy receptor DcR1

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.213

A fifth member of the mammalian G-protein beta-subunit family. Expression in brain and activation of the beta 2 isotype of phospholipase C.

31 March 2020

1 reference

12 December 2020

Nuclear factor-kappaB mediates angiogenesis and metastasis of human bladder cancer through the regulation of interleukin-8.

1 reference

12 December 2020

Regulation of mitogen-activated protein kinase signaling networks by G protein-coupled receptors.

1 reference

12 December 2020

R7BP: a surprising new link between G proteins, RGS proteins, and nuclear signaling in the brain

1 reference

12 December 2020

Prostaglandin EP receptors: targets for treatment and prevention of colorectal cancer?

1 reference

12 December 2020

Inhibition of adenylyl cyclase isoforms V and VI by various Gbetagamma subunits

1 reference

12 December 2020

Immunohistochemical localization of G protein beta1, beta2, beta3, beta4, beta5, and gamma3 subunits in the adult rat brain

1 reference

12 December 2020

The role of cetuximab in the treatment of metastatic colorectal cancer

1 reference

12 December 2020

Identifiers

DOI

10.1038/ONC.2014.213

1 reference

Dimensions Publication ID

8 September 2017

1030652433

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1 reference