(Q38990036)

English

Activation of the constitutive androstane receptor inhibits gluconeogenesis without affecting lipogenesis or fatty acid synthesis in human hepatocytes

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scholarly article

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Europe PubMed Central

PMC publication ID

8 September 2017

Activation of the constitutive androstane receptor inhibits gluconeogenesis without affecting lipogenesis or fatty acid synthesis in human hepatocytes (English)

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

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gluconeogenesis

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based on heuristic

inferred from title

author name string

Caitlin Lynch

1

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

Yongmei Pan

2

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

Linhao Li

3

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

Scott Heyward

4

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

Timothy Moeller

5

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

Peter W Swaan

6

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

Hongbing Wang

7

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Europe PubMed Central

PMC publication ID

8 September 2017

publication date

27 May 2014

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Europe PubMed Central

PMC publication ID

8 September 2017

Toxicology and Applied Pharmacology

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Europe PubMed Central

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8 September 2017

279

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Europe PubMed Central

PMC publication ID

8 September 2017

1

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

33-42

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Europe PubMed Central

PMC publication ID

8 September 2017

describes a project that uses

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Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4118694/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Discovering associations in biomedical datasets by link-based associative classifier (LAC)

1 reference

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Identification of novel activators of constitutive androstane receptor from FDA-approved drugs by integrated computational and biological approaches

1 reference

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1 reference

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1 reference

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Regulation of drug-metabolizing enzymes by xenobiotic receptors: PXR and CAR

1 reference

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A functional cross-talk between liver X receptor-α and constitutive androstane receptor links lipogenesis and xenobiotic responses

1 reference

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1 reference

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1 reference

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Xenobiotic-sensing nuclear receptors CAR and PXR as drug targets in cholestatic liver disease

1 reference

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Activation of nuclear receptor CAR ameliorates diabetes and fatty liver disease

1 reference

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A single amino acid controls the functional switch of human constitutive androstane receptor (CAR) 1 to the xenobiotic-sensitive splicing variant CAR3.

1 reference

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The constitutive androstane receptor is an anti-obesity nuclear receptor that improves insulin sensitivity

1 reference

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PXR and CAR in energy metabolism

1 reference

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Nuclear translocation of adenoviral-enhanced yellow fluorescent protein-tagged-human constitutive androstane receptor (hCAR): a novel tool for screening hCAR activators in human primary hepatocytes

1 reference

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The peripheral benzodiazepine receptor ligand 1-(2-chlorophenyl-methylpropyl)-3-isoquinoline-carboxamide is a novel antagonist of human constitutive androstane receptor

1 reference

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Xenoreceptors CAR and PXR activation and consequences on lipid metabolism, glucose homeostasis, and inflammatory response.

1 reference

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CAR and PXR: the xenobiotic-sensing receptors

1 reference

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The role of the nuclear receptor constitutive androstane receptor in the pathogenesis of non-alcoholic steatohepatitis

1 reference

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CAR, the continuously advancing receptor, in drug metabolism and disease

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Retinoid X receptor-alpha-dependent transactivation by a naturally occurring structural variant of human constitutive androstane receptor (NR1I3).

1 reference

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Nuclear receptors CAR and PXR cross talk with FOXO1 to regulate genes that encode drug-metabolizing and gluconeogenic enzymes

1 reference

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Transcriptional regulation of cytochrome p450 2B genes by nuclear receptors

1 reference

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Role of orphan nuclear receptors in the regulation of drug-metabolising enzymes.

1 reference

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9 September 2017

Identification of a novel human constitutive androstane receptor (CAR) agonist and its use in the identification of CAR target genes

1 reference

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Diverse roles of the nuclear orphan receptor CAR in regulating hepatic genes in response to phenobarbital

1 reference

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The xenobiotic compound 1,4-bis[2-(3,5-dichloropyridyloxy)]benzene is an agonist ligand for the nuclear receptor CAR

1 reference

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Phenobarbital-responsive nuclear translocation of the receptor CAR in induction of the CYP2B gene

1 reference

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Identification of novel breast cancer resistance protein (BCRP) inhibitors by virtual screening

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Regulation of glucose-6-phosphatase gene expression by insulin and metformin.

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Meclizine is an agonist ligand for mouse constitutive androstane receptor (CAR) and an inverse agonist for human CAR.

1 reference

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Constitutive androstane receptor agonist CITCO inhibits growth and expansion of brain tumour stem cells

1 reference

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Enhanced steatosis by nuclear receptor ligands: a study in cultured human hepatocytes and hepatoma cells with a characterized nuclear receptor expression profile.

1 reference

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Constitutive androstane receptor agonist, TCPOBOP, attenuates steatohepatitis in the methionine choline-deficient diet-fed mouse

1 reference

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1 reference

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Xenobiotic stress induces hepatomegaly and liver tumors via the nuclear receptor constitutive androstane receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4118694

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The orphan nuclear receptor constitutive active/androstane receptor is essential for liver tumor promotion by phenobarbital in mice

1 reference

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1 reference

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The role of the nuclear receptor CAR as a coordinate regulator of hepatic gene expression in defense against chemical toxicity.

1 reference

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1 reference

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Cryopreserved human hepatocytes: characterization of drug-metabolizing enzyme activities and applications in higher throughput screening assays for hepatotoxicity, metabolic stability, and drug-drug interaction potential

1 reference

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based on heuristic

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1 reference

https://pubmed.ncbi.nlm.nih.gov/24878338

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.TAAP.2014.05.009

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

8 September 2017

ResearchGate publication ID

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