(Q38991217)

15 June 2018

title

Increase in Pancreatic Proinsulin and Preservation of β-Cell Mass in Autoantibody-Positive Donors Prior to Type 1 Diabetes Onset (English)

1 reference

15 June 2018

0 references

1 reference

Matthias G von Herrath

8

object named as

Matthias G von Herrath

1 reference

15 June 2018

Knut Dahl-Jørgensen

7

object named as

Knut Dahl-Jørgensen

1 reference

15 June 2018

Lars Krogvold

6

object named as

Lars Krogvold

1 reference

15 June 2018

author name string

Teresa Rodriguez-Calvo

1

1 reference

15 June 2018

Jose Zapardiel-Gonzalo

2

1 reference

15 June 2018

Natalie Amirian

3

1 reference

15 June 2018

Ericka Castillo

4

1 reference

15 June 2018

Yasaman Lajevardi

5

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15 June 2018

language of work or name

English

0 references

publication date

30 January 2017

1 reference

15 June 2018

number of pages

12

1 reference

inferred from page(s)

published in

Diabetes

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15 June 2018

volume

66

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15 June 2018

issue

5

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15 June 2018

page(s)

1334-1345

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15 June 2018

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5399615/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Primary Human and Rat β-Cells Release the Intracellular Autoantigens GAD65, IA-2, and Proinsulin in Exosomes Together With Cytokine-Induced Enhancers of Immunity.

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Analysis of self-antigen specificity of islet-infiltrating T cells from human donors with type 1 diabetes.

17 June 2018

1 reference

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Peripheral Proinsulin Expression Controls Low-Avidity Proinsulin-Reactive CD8 T Cells in Type 1 Diabetes.

17 June 2018

1 reference

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Elevations in the Fasting Serum Proinsulin-to-C-Peptide Ratio Precede the Onset of Type 1 Diabetes

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399615

Viral infections in type 1 diabetes mellitus--why the β cells?

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399615

Proinsulin Expression Shapes the TCR Repertoire but Fails to Control the Development of Low-Avidity Insulin-Reactive CD8+ T Cells.

17 June 2018

1 reference

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Insulitis and β-Cell Mass in the Natural History of Type 1 Diabetes.

17 June 2018

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β cell ER stress and the implications for immunogenicity in type 1 diabetes

17 June 2018

1 reference

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Proinsulin and heat shock protein 90 as biomarkers of beta-cell stress in the early period after onset of type 1 diabetes

17 June 2018

1 reference

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A run on the biobank: what have we learned about type 1 diabetes from the nPOD tissue repository?

17 June 2018

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Organ donor specimens: What can they tell us about type 1 diabetes?

17 June 2018

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Predicting type 1 diabetes using biomarkers

17 June 2018

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Function of Isolated Pancreatic Islets From Patients at Onset of Type 1 Diabetes: Insulin Secretion Can Be Restored After Some Days in a Nondiabetogenic Environment In Vitro: Results From the DiViD Study

17 June 2018

1 reference

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Proinsulin misfolding and endoplasmic reticulum stress during the development and progression of diabetes

17 June 2018

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Detection of a low-grade enteroviral infection in the islets of langerhans of living patients newly diagnosed with type 1 diabetes

17 June 2018

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New insight on human type 1 diabetes biology: nPOD and nPOD-transplantation.

17 June 2018

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Proinsulin entry and transit through the endoplasmic reticulum in pancreatic beta cells

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399615

Seroconversion to multiple islet autoantibodies and risk of progression to diabetes in children

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399615

Proinsulin intermolecular interactions during secretory trafficking in pancreatic β cells

17 June 2018

1 reference

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The multiple origins of Type 1 diabetes

17 June 2018

1 reference

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The impact of the unfolded protein response on human disease

17 June 2018

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The metabolic progression to type 1 diabetes as indicated by serial oral glucose tolerance testing in the Diabetes Prevention Trial-type 1.

17 June 2018

1 reference

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Metabolic regulation in progression to autoimmune diabetes

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399615

Type 1 diabetes: etiology, immunology, and therapeutic strategies

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399615

Quantification and three-dimensional imaging of the insulitis-induced destruction of beta-cells in murine type 1 diabetes

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399615

ER stress in pancreatic beta cells: the thin red line between adaptation and failure

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399615

Dysregulation of lipid and amino acid metabolism precedes islet autoimmunity in children who later progress to type 1 diabetes

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399615

Recognition of human proinsulin leader sequence by class I-restricted T-cells in HLA-A*0201 transgenic mice and in human type 1 diabetes

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399615

Screening for insulitis in adult autoantibody-positive organ donors

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399615

Recognition of a subregion of human proinsulin by class I-restricted T cells in type 1 diabetic patients

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399615

Proinsulin-a pathogenic autoantigen in type 1 diabetes.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399615

Type I diabetes mellitus. A chronic autoimmune disease

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399615

Islet-Derived CD4 T Cells Targeting Proinsulin in Human Autoimmune Diabetes

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399615

Spatial and temporal dynamics of innervation during the development of fetal human pancreas.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399615

Induction of pancreatic differentiation by signals from blood vessels.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399615

Longitudinal study of fasting proinsulin in 148 siblings of patients with insulin-dependent diabetes mellitus. Study Group on Childhood Diabetes in Finland.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399615

Disproportionately elevated proinsulin levels precede the onset of insulin-dependent diabetes mellitus in siblings with low first phase insulin responses. The Childhood Diabetes in Finland Study Group.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399615

Pre-type I diabetes. Linear loss of beta cell response to intravenous glucose.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5399615

Prolonged exposure of human beta-cells to high glucose increases their release of proinsulin during acute stimulation with glucose or arginine

21 August 2018

1 reference

12 December 2020

Proinsulin levels and the proinsulin:c-peptide ratio complement autoantibody measurement for predicting type 1 diabetes

1 reference

12 December 2020

CD8+ T-cell responses identify beta-cell autoimmunity in human type 1 diabetes

1 reference

12 December 2020

β-cell Mass in Nondiabetic Autoantibody-Positive Subjects: An Analysis Based on the Network for Pancreatic Organ Donors Database

1 reference

12 December 2020

Lack of immunohistological changes in the islets of nondiabetic, autoimmune, polyendocrine patients with beta-selective GAD-specific islet cell antibodies

1 reference

12 December 2020

HbA1c Predicts Time to Diagnosis of Type 1 Diabetes in Children at Risk

1 reference

12 December 2020

Pancreatic biopsy by minimal tail resection in live adult patients at the onset of type 1 diabetes: experiences from the DiViD study

1 reference

12 December 2020

Identifiers

DOI

10.2337/DB16-1343

1 reference

15 June 2018

PMC publication ID

5399615

1 reference

15 June 2018

PubMed publication ID

28137793

1 reference

15 June 2018