(Q39004999)

8 September 2017

Geranyl and neryl triazole bisphosphonates as inhibitors of geranylgeranyl diphosphate synthase (English)

1 reference

8 September 2017

Xiang Zhou

1

1 reference

8 September 2017

Sarah D Ferree

2

1 reference

8 September 2017

Veronica S Wills

3

1 reference

8 September 2017

Ella J Born

4

1 reference

8 September 2017

Huaxiang Tong

5

1 reference

8 September 2017

David F Wiemer

6

1 reference

8 September 2017

Sarah A Holstein

7

1 reference

8 September 2017

language of work or name

English

0 references

publication date

24 March 2014

1 reference

Bioorganic & Medicinal Chemistry

8 September 2017

1 reference

8 September 2017

22

1 reference

8 September 2017

9

1 reference

8 September 2017

2791-2798

1 reference

Chemo-Immunotherapeutic Antimalarials Targeting Isoprenoid Biosynthesis

8 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067939

Novel functions for Rab GTPases in multiple aspects of tumour progression

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067939

Is there a future for prenyltransferase inhibitors in cancer therapy?

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067939

Geranylgeranyl diphosphate synthase: an emerging therapeutic target

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067939

Structures of RabGGTase-substrate/product complexes provide insights into the evolution of protein prenylation

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067939

Farnesyltransferase inhibitors: a detailed chemical view on an elusive biological problem

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067939

Isoprenoids: remarkable diversity of form and function

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067939

Phase separation of integral membrane proteins in Triton X-114 solution

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067939

Triazole-based inhibitors of geranylgeranyltransferase II.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067939

Bisphosphonates induce autophagy by depleting geranylgeranyl diphosphate

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067939

Isoprenoid biosynthetic pathway inhibition disrupts monoclonal protein secretion and induces the unfolded protein response pathway in multiple myeloma cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067939

Pivaloyloxymethyl-modified isoprenoid bisphosphonates display enhanced inhibition of cellular geranylgeranylation

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067939

Digeranyl bisphosphonate inhibits geranylgeranyl pyrophosphate synthase.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067939

Synthesis and biological activity of isoprenoid bisphosphonates

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067939

A fluorescence assay for geranylgeranyl transferase type I.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067939

Simultaneous determination of farnesyl and geranylgeranyl pyrophosphate levels in cultured cells

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067939

Prenylation assays for small GTPases

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067939

Inhibition of geranylgeranyl diphosphate synthase induces apoptosis through multiple mechanisms and displays synergy with inhibition of other isoprenoid biosynthetic enzymes.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067939

Mono- and dialkyl isoprenoid bisphosphonates as geranylgeranyl diphosphate synthase inhibitors

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067939

Phosphonate and bisphosphonate analogues of farnesyl pyrophosphate as potential inhibitors of farnesyl protein transferase

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067939

Novel farnesol and geranylgeraniol analogues: A potential new class of anticancer agents directed against protein prenylation

21 August 2018

1 reference

12 December 2020

Continuous fluorescence assay for protein prenyltransferases

1 reference

12 December 2020

Stereochemistry-dependent inhibition of RAS farnesylation by farnesyl phosphonic acids

1 reference

12 December 2020

Synthesis of functionalized bisphosphonates via click chemistry

1 reference

12 December 2020

10.1016/J.BMC.2014.03.014

Identifiers

DOI

1 reference

8 September 2017

1 reference

8 September 2017

PubMed publication ID

24726306

1 reference