(Q39010613)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27853778%20AND%20SRC:MED&resulttype=core&format=json

27 March 2020

review article

1 reference

title

Diversity of nature's assembly lines - recent discoveries in non-ribosomal peptide synthesis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27853778%20AND%20SRC:MED&resulttype=core&format=json

27 March 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27853778%20AND%20SRC:MED&resulttype=core&format=json

27 March 2020

Max J Cryle

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27853778%20AND%20SRC:MED&resulttype=core&format=json

27 March 2020

author name string

Melanie Schoppet

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27853778%20AND%20SRC:MED&resulttype=core&format=json

27 March 2020

Mathias Henning Hansen

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27853778%20AND%20SRC:MED&resulttype=core&format=json

27 March 2020

publication date

1 December 2016

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27853778%20AND%20SRC:MED&resulttype=core&format=json

27 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27853778%20AND%20SRC:MED&resulttype=core&format=json

27 March 2020

volume

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27853778%20AND%20SRC:MED&resulttype=core&format=json

27 March 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27853778%20AND%20SRC:MED&resulttype=core&format=json

27 March 2020

page(s)

9-22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27853778%20AND%20SRC:MED&resulttype=core&format=json

Prospects for new antibiotics: a molecule-centered perspective

27 March 2020

cites work

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

Nonribosomal peptide synthetases involved in the production of medically relevant natural products

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

Assembly-line enzymology for polyketide and nonribosomal Peptide antibiotics: logic, machinery, and mechanisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

New Structural Data Reveal the Motion of Carrier Proteins in Nonribosomal Peptide Synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

Synthetic biology of secondary metabolite biosynthesis in actinomycetes: Engineering precursor supply as a way to optimize antibiotic production

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

Glycopeptide biosynthesis in the context of basic cellular functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

Structures of a Nonribosomal Peptide Synthetase Module Bound to MbtH-Like Proteins Support a Highly Dynamic Domain Architecture

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

Structures of two distinct conformations of holo-non-ribosomal peptide synthetases

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

Chemical Probes Allow Structural Insight into the Condensation Reaction of Nonribosomal Peptide Synthetases

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

The structure of a transient complex of a nonribosomal peptide synthetase and a cytochrome P450 monooxygenase

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

Trapping the dynamic acyl carrier protein in fatty acid biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

Crystal structure of the termination module of a nonribosomal peptide synthetase

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

The structural biology of biosynthetic megaenzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

A mechanism-based aryl carrier protein/thiolation domain affinity probe

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

Stereocontrolled syntheses of peptide thioesters containing modified seryl residues as probes of antibiotic biosynthesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

β-Lactam formation by a non-ribosomal peptide synthetase during antibiotic biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

Epimerization and substrate gating by a TE domain in β-lactam antibiotic biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

Regulation of the P450 Oxygenation Cascade Involved in Glycopeptide Antibiotic Biosynthesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

X-domain of peptide synthetases recruits oxygenases crucial for glycopeptide biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

A facile Fmoc solid phase synthesis strategy to access epimerization-prone biosynthetic intermediates of glycopeptide antibiotics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

Rapid access to glycopeptide antibiotic precursor peptides coupled with cytochrome P450-mediated catalysis: towards a biomimetic synthesis of glycopeptide antibiotics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

Second-generation probes for biosynthetic intermediate capture: towards a comprehensive profiling of polyketide assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

Chemical probes for the functionalization of polyketide intermediates

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

Recent advances in engineering nonribosomal peptide assembly lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

Active-site modifications of adenylation domains lead to hydrolysis of upstream nonribosomal peptidyl thioester intermediates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

Structure, biosynthetic origin, and engineered biosynthesis of calcium-dependent antibiotics from Streptomyces coelicolor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

Combinatorial biosynthesis of cyclic lipopeptide antibiotics: a model for synthetic biology to accelerate the evolution of secondary metabolite biosynthetic pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

Conformational dynamics in the Acyl-CoA synthetases, adenylation domains of non-ribosomal peptide synthetases, and firefly luciferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

Nonproteinogenic amino acid building blocks for nonribosomal peptide and hybrid polyketide scaffolds

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

The crystal structure of the adenylation enzyme VinN reveals a unique β-amino acid recognition mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

The gyrase inhibitor albicidin consists of p-aminobenzoic acids and cyanoalanine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

Cloning and biochemical characterization of the hectochlorin biosynthetic gene cluster from the marine cyanobacterium Lyngbya majuscula

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

A ketoreductase domain in the PksJ protein of the bacillaene assembly line carries out both alpha- and beta-ketone reduction during chain growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

Expanding Substrate Promiscuity by Engineering a Novel Adenylating-Methylating NRPS Bifunctional Enzyme.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

Interrupted adenylation domains: unique bifunctional enzymes involved in nonribosomal peptide biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

Non-ribosomal propeptide precursor in nocardicin A biosynthesis predicted from adenylation domain specificity dependent on the MbtH family protein NocI.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

Role of MbtH-like proteins in the adenylation of tyrosine during aminocoumarin and vancomycin biosynthesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

MbtH-like proteins as integral components of bacterial nonribosomal peptide synthetases

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

Online Pyrophosphate Assay for Analyzing Adenylation Domains of Nonribosomal Peptide Synthetases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

An Activator of an Adenylation Domain Revealed by Activity but Not Sequence Homology

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

Analysis of the linker region joining the adenylation and carrier protein domains of the modular nonribosomal peptide synthetases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

Structural Elucidation of the Bispecificity of A Domains as a Basis for Activating Non-natural Amino Acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

Mutasynthesis of glycopeptide antibiotics: variations of vancomycin's AB-ring amino acid 3,5-dihydroxyphenylglycine

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

Fluorobalhimycin--a new chapter in glycopeptide antibiotic research

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

The linear pentadecapeptide gramicidin is assembled by four multimodular nonribosomal peptide synthetases that comprise 16 modules with 56 catalytic domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

Cyanobacterial peptides - nature's own combinatorial biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

Peptide bond formation in nonribosomal peptide biosynthesis. Catalytic role of the condensation domain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

Structural and functional insights into a peptide bond-forming bidomain from a nonribosomal peptide synthetase

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

Daptomycin, a bacterial lipopeptide synthesized by a nonribosomal machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

Biosynthetic gene cluster of the non-ribosomally synthesized cyclodepsipeptide skyllamycin: deciphering unprecedented ways of unusual hydroxylation reactions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

Crystal structures of the first condensation domain of CDA synthetase suggest conformational changes during the synthetic cycle of nonribosomal peptide synthetases

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

Explorations of catalytic domains in non-ribosomal peptide synthetase enzymology

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

From thioesters to amides and back: condensation domain reversibility in the biosynthesis of vibriobactin

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

Phylogenetic analysis of condensation domains in NRPS sheds light on their functional evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

Interdomain and Intermodule Organization in Epimerization Domain Containing Nonribosomal Peptide Synthetases

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

Structure of the epimerization domain of tyrocidine synthetase A

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

Utility of epimerization domains for the redesign of nonribosomal peptide synthetases

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

Generation of D amino acid residues in assembly of arthrofactin by dual condensation/epimerization domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

The enzymes of β-lactam biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

More than just recruitment: the X-domain influences catalysis of the first phenolic coupling reaction in A47934 biosynthesis by Cytochrome P450 StaH

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

Understanding the crucial interactions between Cytochrome P450s and non-ribosomal peptide synthetases during glycopeptide antibiotic biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

The biosynthesis of teicoplanin-type glycopeptide antibiotics: assignment of p450 mono-oxygenases to side chain cyclizations of glycopeptide a47934.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

Genetic analysis of the balhimycin (vancomycin-type) oxygenase genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

Oxidative phenol coupling reactions catalyzed by OxyB: a cytochrome P450 from the vancomycin producing organism. implications for vancomycin biosynthesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

An oxidative phenol coupling reaction catalyzed by oxyB, a cytochrome P450 from the vancomycin-producing microorganism

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

The biosynthesis of vancomycin-type glycopeptide antibiotics--a model for oxidative side-chain cross-linking by oxygenases coupled to the action of peptide synthetases

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

F-O-G Ring Formation in Glycopeptide Antibiotic Biosynthesis is Catalysed by OxyE.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

Polyketide synthase and non-ribosomal peptide synthetase thioesterase selectivity: logic gate or a victim of fate?

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

Regeneration of misprimed nonribosomal peptide synthetases by type II thioesterases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

Generating Functional Recombinant NRPS Enzymes in the Laboratory Setting via Peptidyl Carrier Protein Engineering.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

Cloning and characterization of a Streptomyces single module type non-ribosomal peptide synthetase catalyzing a blue pigment synthesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

Structural Basis for Phosphopantetheinyl Carrier Domain Interactions in the Terminal Module of Nonribosomal Peptide Synthetases

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

Peptide cyclization catalysed by the thioesterase domain of tyrocidine synthetase

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

Reconstituted biosynthesis of the nonribosomal macrolactone antibiotic valinomycin in Escherichia coli.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

Structural aspects of phenylglycines, their biosynthesis and occurrence in peptide natural products.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

A Peptidyl-Transesterifying Type I Thioesterase in Salinamide Biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

Reprogramming the Biosynthesis of Cyclodepsipeptide Synthetases to Obtain New Enniatins and Beauvericins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

Genetics and assembly line enzymology of siderophore biosynthesis in bacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

Cytochrome p450sky interacts directly with the nonribosomal peptide synthetase to generate three amino acid precursors in skyllamycin biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

Diversity of P450 enzymes in the biosynthesis of natural products

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

Carrier protein substrates in cytochrome P450-catalysed oxidation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

Structural insights from a P450 Carrier Protein complex reveal how specificity is achieved in the P450BioI ACP complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

Cytochrome P450–catalyzed L-tryptophan nitration in thaxtomin phytotoxin biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

Structural Characterization of OxyD, a Cytochrome P450 Involved in -Hydroxytyrosine Formation in Vancomycin Biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

Specific Enzymatic Halogenation-From the Discovery of Halogenated Enzymes to Their Applications In Vitro and In Vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

The biosynthetic gene cluster for the antitumor drug bleomycin from Streptomyces verticillus ATCC15003 supporting functional interactions between nonribosomal peptide synthetases and a polyketide synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

A structural model for multimodular NRPS assembly lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

Harnessing the potential of communication-mediating domains for the biocombinatorial synthesis of nonribosomal peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

Mapping of the Communication-Mediating Interface in Nonribosomal Peptide Synthetases Using a Genetically Encoded Photocrosslinker Supports an Upside-Down Helix-Hand Motif.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC6MB00675B

New Advances in the Biosynthesis of Glycopeptide Antibiotics of the Vancomycin Type fromAmycolatopsis mediterranei

21 January 2018

1 reference

11 May 2024

https://opencitations.net/index/api/v1/citations/10.1002/(SICI)1521-3773(19990712)38:13/14%3C1976::AID-ANIE1976%3E3.0.CO;2-3

Identifiers

DOI

10.1039/C6MB00675B

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27853778%20AND%20SRC:MED&resulttype=core&format=json

27 March 2020

1 reference