(Q39011040)

8 September 2017

Differential activity of GSK-3 isoforms regulates NF-κB and TRAIL- or TNFα induced apoptosis in pancreatic cancer cells (English)

1 reference

8 September 2017

0 references

1 reference

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24675460%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Scott H Kaufmann

11

1 reference

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11 June 2020

12

D D Billadeau

1 reference

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11 June 2020

author name string

J-S Zhang

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24675460%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

M Herreros-Villanueva

2

1 reference

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11 June 2020

A Koenig

3

1 reference

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11 June 2020

Z Deng

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24675460%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

A A-M de Narvajas

5

1 reference

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11 June 2020

T S Gomez

6

1 reference

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11 June 2020

X Meng

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24675460%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

V Ellenrieder

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24675460%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

X K Li

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24675460%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

publication date

27 March 2014

1 reference

8 September 2017

Cell Death and Disease

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24675460%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

volume

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24675460%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

page(s)

e1142

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24675460%20AND%20SRC:MED&resulttype=core&format=json

Death receptors as targets in cancer

11 June 2020

cites work

1 reference

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Non-canonical kinase signaling by the death ligand TRAIL in cancer cells: discord in the death receptor family

9 September 2017

1 reference

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DDX3 regulates DNA damage-induced apoptosis and p53 stabilization

9 September 2017

1 reference

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Aberrant glycogen synthase kinase 3β is involved in pancreatic cancer cell invasion and resistance to therapy

9 September 2017

1 reference

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Design of glycogen synthase kinase-3 inhibitors: an overview on recent advancements.

9 September 2017

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Aberrant glycogen synthase kinase 3β in the development of pancreatic cancer

9 September 2017

1 reference

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Novel reporter alleles of GSK-3α and GSK-3β

9 September 2017

1 reference

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c-FLIP, a master anti-apoptotic regulator

9 September 2017

1 reference

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Glycogen synthase kinase-3 inhibition sensitizes pancreatic cancer cells to TRAIL-induced apoptosis

9 September 2017

1 reference

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Translating TRAIL-receptor targeting agents to the clinic.

9 September 2017

1 reference

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NF-κB as a target for pancreatic cancer therapy.

9 September 2017

1 reference

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Dimer-specific regulatory mechanisms within the NF-κB family of transcription factors

9 September 2017

1 reference

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High cell surface death receptor expression determines type I versus type II signaling

9 September 2017

1 reference

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GRB2 couples RhoU to epidermal growth factor receptor signaling and cell migration

9 September 2017

1 reference

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Mutant K-Ras increases GSK-3β gene expression via an ETS-p300 transcriptional complex in pancreatic cancer

9 September 2017

1 reference

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Impact of death receptor signaling on the malignancy of pancreatic ductal adenocarcinoma

9 September 2017

1 reference

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Targeting apoptosis pathways in pancreatic cancer

9 September 2017

1 reference

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New insights into apoptosis signaling by Apo2L/TRAIL.

9 September 2017

1 reference

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The regulatory logic of the NF-kappaB signaling system

9 September 2017

1 reference

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Playing the DISC: turning on TRAIL death receptor-mediated apoptosis in cancer

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067531

Regulation of protein stability by GSK3 mediated phosphorylation

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067531

Apoptosis pathways and their therapeutic exploitation in pancreatic cancer

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067531

Targeting the extrinsic apoptosis pathway in cancer

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067531

TRAIL and cancer therapy.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067531

Aberrant nuclear accumulation of glycogen synthase kinase-3beta in human pancreatic cancer: association with kinase activity and tumor dedifferentiation

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067531

The paradoxical pro- and anti-apoptotic actions of GSK3 in the intrinsic and extrinsic apoptosis signaling pathways

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067531

Exploiting death receptor signaling pathways for tumor therapy

9 September 2017

1 reference

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Phosphorylation of serine 468 by GSK-3beta negatively regulates basal p65 NF-kappaB activity

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067531

GSK-3: tricks of the trade for a multi-tasking kinase

9 September 2017

1 reference

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CD95 and TRAIL receptor-mediated activation of protein kinase C and NF-kappaB contributes to apoptosis resistance in ductal pancreatic adenocarcinoma cells

9 September 2017

1 reference

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A conserved alpha-helical motif mediates the interaction of Sp1-like transcriptional repressors with the corepressor mSin3A

9 September 2017

1 reference

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Requirement for glycogen synthase kinase-3beta in cell survival and NF-kappaB activation

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067531

A new alpha in line between KRAS and NF-κB activation?

9 September 2017

1 reference

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GSK-3α promotes oncogenic KRAS function in pancreatic cancer via TAK1-TAB stabilization and regulation of noncanonical NF-κB.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067531

GSK-3α and GSK-3β proteins are involved in early stages of chondrocyte differentiation with functional redundancy through RelA protein phosphorylation

9 September 2017

1 reference

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GSK-3α is a central regulator of age-related pathologies in mice

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067531

TRAIL-induced apoptosis is preferentially mediated via TRAIL receptor 1 in pancreatic carcinoma cells and profoundly enhanced by XIAP inhibitors

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067531

Principles of dimer-specific gene regulation revealed by a comprehensive characterization of NF-κB family DNA binding

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067531

Functional redundancy of GSK-3alpha and GSK-3beta in Wnt/beta-catenin signaling shown by using an allelic series of embryonic stem cell lines

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067531

Role of caspases in CD95L- and TRAIL-induced non-apoptotic signalling in pancreatic tumour cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067531

Constitutively activated nuclear factor-kappaB, but not induced NF-kappaB, leads to TRAIL resistance by up-regulation of X-linked inhibitor of apoptosis protein in human cancer cells.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067531

Glycogen synthase kinase 3beta functions to specify gene-specific, NF-kappaB-dependent transcription

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067531

Predominant Bcl-XL knockdown disables antiapoptotic mechanisms: tumor necrosis factor-related apoptosis-inducing ligand-based triple chemotherapy overcomes chemoresistance in pancreatic cancer cells in vitro

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067531

Glycogen synthase kinase-3beta participates in nuclear factor kappaB-mediated gene transcription and cell survival in pancreatic cancer cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067531

Glycogen synthase kinase-3beta suppression eliminates tumor necrosis factor-related apoptosis-inducing ligand resistance in prostate cancer

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067531

SOX2 promotes dedifferentiation and imparts stem cell-like features to pancreatic cancer cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067531

Maintenance of constitutive IkappaB kinase activity by glycogen synthase kinase-3alpha/beta in pancreatic cancer

17 June 2018

1 reference

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Identification of c-FLIP(L) and c-FLIP(S) as critical regulators of death receptor-induced apoptosis in pancreatic cancer cells

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067531

Small molecule XIAP inhibitors enhance TRAIL-induced apoptosis and antitumor activity in preclinical models of pancreatic carcinoma.

21 August 2018

1 reference

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Chemical rescue of cleft palate and midline defects in conditional GSK-3beta mice.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067531

Glycogen synthase kinase-3 beta regulates NF-kappa B1/p105 stability

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4067531

Targeting XIAP Bypasses Bcl-2-Mediated Resistance to TRAIL and Cooperates with TRAIL to Suppress Pancreatic Cancer Growth In vitro and In vivo

21 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FCDDIS.2014.102

Bcl-XL protects pancreatic adenocarcinoma cells against CD95- and TRAIL-receptor-mediated apoptosis

21 January 2018

1 reference

12 December 2020

Role of glycogen synthase kinase-3 in TNF-alpha-induced NF-kappaB activation and apoptosis in hepatocytes

1 reference

12 December 2020

Nuclear factor-kappaB maintains TRAIL resistance in human pancreatic cancer cells

1 reference

12 December 2020

TRAIL promotes metastasis of human pancreatic ductal adenocarcinoma

1 reference

12 December 2020

Genetic deletion of glycogen synthase kinase-3beta abrogates activation of IkappaBalpha kinase, JNK, Akt, and p44/p42 MAPK but potentiates apoptosis induced by tumor necrosis factor

1 reference

12 December 2020

Identifiers

DOI

10.1038/CDDIS.2014.102

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24675460%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

11 June 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24675460%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

PubMed publication ID

24675460

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24675460%20AND%20SRC:MED&resulttype=core&format=json