(Q39011822)

8 September 2017

SGI-110 and entinostat therapy reduces lung tumor burden and reprograms the epigenome (English)

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8 September 2017

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9

Steven A Belinsky

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8 September 2017

Carmen S Tellez

1

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8 September 2017

Marcie J Grimes

2

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8 September 2017

Maria A Picchi

3

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8 September 2017

Yushi Liu

4

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8 September 2017

Thomas H March

5

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8 September 2017

Matthew D Reed

6

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8 September 2017

Aram Oganesian

7

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8 September 2017

Pietro Taverna

8

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8 September 2017

language of work or name

English

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publication date

5 April 2014

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International Journal of Cancer

8 September 2017

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8 September 2017

135

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8 September 2017

2223-2231

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8 September 2017

9

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Covalent bond formation between a DNA-cytosine methyltransferase and DNA containing 5-azacytosine

8 September 2017

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Epigenetic therapy of cancer: past, present and future

21 January 2018

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The absence of p53 is critical for the induction of apoptosis by 5-aza-2'-deoxycytidine

21 January 2018

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HDAC inhibitors act with 5-aza-2'-deoxycytidine to inhibit cell proliferation by suppressing removal of incorporated abases in lung cancer cells

21 January 2018

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Preclinical studies on histone deacetylase inhibitors as therapeutic reagents for endometrial and ovarian cancers

21 January 2018

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Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer

21 January 2018

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HDAC inhibitors and decitabine are highly synergistic and associated with unique gene-expression and epigenetic profiles in models of DLBCL

21 January 2018

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Reactivating the expression of methylation silenced genes in human cancer

21 January 2018

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Targeting DNA methylation

21 January 2018

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Cellular differentiation, cytidine analogs and DNA methylation

21 January 2018

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5-Azacytidine and 5-aza-2'-deoxycytidine as inhibitors of DNA methylation: mechanistic studies and their implications for cancer therapy

21 January 2018

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S110, a 5-Aza-2'-deoxycytidine-containing dinucleotide, is an effective DNA methylation inhibitor in vivo and can reduce tumor growth

21 January 2018

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Delivery of 5-aza-2'-deoxycytidine to cells using oligodeoxynucleotides

21 January 2018

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Histone acetylation in chromatin structure and transcription

21 January 2018

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Role of covalent modifications of histones in regulating gene expression

21 January 2018

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Dynamics of histone acetylation in vivo. A function for acetylation turnover?

21 January 2018

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Transcriptional control at regulatory checkpoints by histone deacetylases: molecular connections between cancer and chromatin

21 January 2018

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Histone acetylation and transcriptional regulatory mechanisms

21 January 2018

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Identification and functional significance of genes regulated by structurally different histone deacetylase inhibitors

21 January 2018

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Apoptotic and autophagic cell death induced by histone deacetylase inhibitors

21 January 2018

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Histone deacetylase inhibitors: inducers of differentiation or apoptosis of transformed cells

21 January 2018

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Histone deacetylase inhibitor trichostatin A induces cell-cycle arrest/apoptosis and hepatocyte differentiation in human hepatoma cells

21 January 2018

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Histone deacetylase inhibitors induce growth arrest, apoptosis, and differentiation in clear cell sarcoma models

21 January 2018

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A genomic screen for genes upregulated by demethylation and histone deacetylase inhibition in human colorectal cancer

21 January 2018

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Antineoplastic action of 5-aza-2'-deoxycytidine and histone deacetylase inhibitor and their effect on the expression of retinoic acid receptor beta and estrogen receptor alpha genes in breast carcinoma cells

21 January 2018

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Combination epigenetic therapy has efficacy in patients with refractory advanced non-small cell lung cancer

21 January 2018

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Refinement of an orthotopic lung cancer model in the nude rat.

21 January 2018

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Combination therapy with vidaza and entinostat suppresses tumor growth and reprograms the epigenome in an orthotopic lung cancer model

21 January 2018

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Aerosolised 5-azacytidine suppresses tumour growth and reprogrammes the epigenome in an orthotopic lung cancer model

21 January 2018

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Phase I and pharmacokinetic study of MS-275, a histone deacetylase inhibitor, in patients with advanced and refractory solid tumors or lymphoma

21 January 2018

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A phase I and pharmacokinetic study of the oral histone deacetylase inhibitor, MS-275, in patients with refractory solid tumors and lymphomas

21 January 2018

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The polycomb group protein EZH2 is involved in progression of prostate cancer

21 January 2018

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The Polycomb group protein EZH2 directly controls DNA methylation

21 January 2018

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Phase I study of decitabine-mediated gene expression in patients with cancers involving the lungs, esophagus, or pleura

21 January 2018

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Immunomodulatory activity of SGI-110, a 5-aza-2'-deoxycytidine-containing demethylating dinucleotide.

21 January 2018

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DNA methyltransferase Dnmt1 associates with histone deacetylase activity

21 January 2018

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DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci

21 January 2018

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Suv39h-mediated histone H3 lysine 9 methylation directs DNA methylation to major satellite repeats at pericentric heterochromatin

21 January 2018

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5-azacytidine treatment reorganizes genomic histone modification patterns

21 January 2018

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High cytidine deaminase expression in the liver provides sanctuary for cancer cells from decitabine treatment effects.

21 January 2018

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Effects of tetrahydrouridine on pharmacokinetics and pharmacodynamics of oral decitabine

21 January 2018

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Epigenetic resensitization to platinum in ovarian cancer

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/IJC.28865

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8 September 2017

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