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English
Necroptosis induced by RIPK3 requires MLKL but not Drp1.
scientific article published on 27 February 2014
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PMCID
3944236
retrieved
8 September 2017
title
Necroptosis induced by RIPK3 requires MLKL but not Drp1.
(English)
1 reference
stated in
Europe PubMed Central
PMCID
3944236
retrieved
8 September 2017
main subject
necroptosis
1 reference
based on heuristic
inferred from title
author
James Murphy
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMCID
3944236
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24577084%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 June 2020
David L Vaux
series ordinal
4
1 reference
stated in
Europe PubMed Central
PMCID
3944236
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24577084%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 June 2020
author name string
D M Moujalled
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
3944236
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24577084%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 June 2020
W D Cook
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMCID
3944236
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24577084%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 June 2020
publication date
27 February 2014
1 reference
stated in
Europe PubMed Central
PMCID
3944236
retrieved
8 September 2017
published in
Cell Death and Disease
1 reference
stated in
Europe PubMed Central
PMCID
3944236
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24577084%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 June 2020
volume
5
1 reference
stated in
Europe PubMed Central
PMCID
3944236
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24577084%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 June 2020
page(s)
e1086
1 reference
stated in
Europe PubMed Central
PMCID
3944236
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24577084%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 June 2020
exact match
https://scigraph.springernature.com/pub.10.1038/cddis.2014.18
0 references
cites work
RIPK1- and RIPK3-induced cell death mode is determined by target availability
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944236
retrieved
9 September 2017
The pseudokinase MLKL mediates necroptosis via a molecular switch mechanism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944236
retrieved
9 September 2017
The mitochondrial phosphatase PGAM5 functions at the convergence point of multiple necrotic death pathways
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944236
retrieved
9 September 2017
Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of RIP3 kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944236
retrieved
9 September 2017
Many stimuli pull the necrotic trigger, an overview
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944236
retrieved
9 September 2017
The dynamin-related GTPase Drp1 is required for embryonic and brain development in mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944236
retrieved
9 September 2017
Mitochondrial fission factor Drp1 is essential for embryonic development and synapse formation in mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944236
retrieved
9 September 2017
Caspase-independent type III programmed cell death in chronic lymphocytic leukemia: the key role of the F-actin cytoskeleton
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944236
retrieved
9 September 2017
Identification of RIP1 kinase as a specific cellular target of necrostatins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944236
retrieved
9 September 2017
Chemical inhibition of the mitochondrial division dynamin reveals its role in Bax/Bak-dependent mitochondrial outer membrane permeabilization
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944236
retrieved
9 September 2017
IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944236
retrieved
9 September 2017
The pyroptosome: a supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944236
retrieved
9 September 2017
Inhibiting the mitochondrial fission machinery does not prevent Bax/Bak-dependent apoptosis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944236
retrieved
9 September 2017
Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944236
retrieved
9 September 2017
Tumor necrosis factor: an apoptosis JuNKie?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944236
retrieved
9 September 2017
Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944236
retrieved
9 September 2017
The role of dynamin-related protein 1, a mediator of mitochondrial fission, in apoptosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944236
retrieved
9 September 2017
BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944236
retrieved
9 September 2017
Pro-apoptotic cascade activates BID, which oligomerizes BAK or BAX into pores that result in the release of cytochrome c.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944236
retrieved
9 September 2017
TRAIL receptor-2 signals apoptosis through FADD and caspase-8
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944236
retrieved
9 September 2017
An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944236
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9 September 2017
Essential requirement for caspase-8/FLICE in the initiation of the Fas-induced apoptotic cascade
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944236
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9 September 2017
Death receptors: signaling and modulation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944236
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9 September 2017
Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944236
retrieved
9 September 2017
Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-kappaB activation prevents cell death
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944236
retrieved
9 September 2017
Activation of the Raf-1 kinase cascade by coumermycin-induced dimerization.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944236
retrieved
9 September 2017
TNF can activate RIPK3 and cause programmed necrosis in the absence of RIPK1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944236
retrieved
9 September 2017
Activation of caspase-1 by the NLRP3 inflammasome regulates the NADPH oxidase NOX2 to control phagosome function
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944236
retrieved
17 June 2018
Drp1 mediates caspase-independent type III cell death in normal and leukemic cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944236
retrieved
17 June 2018
Inhibitor of apoptosis proteins limit RIP3 kinase-dependent interleukin-1 activation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944236
retrieved
21 August 2018
A chemical inhibitor of DRP1 uncouples mitochondrial fission and apoptosis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944236
retrieved
21 August 2018
Bax/Bak-dependent release of DDP/TIMM8a promotes Drp1-mediated mitochondrial fission and mitoptosis during programmed cell death
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944236
retrieved
21 August 2018
Q-VD-OPh, a broad spectrum caspase inhibitor with potent antiapoptotic properties
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3944236
retrieved
21 August 2018
Cytoplasmic p53 is not required for PUMA-induced apoptosis
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24577084
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Inhibiting Drp1-mediated mitochondrial fission selectively prevents the release of cytochrome c during apoptosis
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24577084
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1038/CDDIS.2014.18
1 reference
stated in
Europe PubMed Central
PMCID
3944236
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24577084%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 June 2020
Dimensions Publication ID
1036070237
0 references
PMCID
3944236
1 reference
stated in
Europe PubMed Central
PMCID
3944236
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24577084%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 June 2020
PubMed ID
24577084
1 reference
stated in
Europe PubMed Central
PMCID
3944236
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24577084%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 June 2020
ResearchGate publication ID
260430344
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