(Q39026274)

8 September 2017

title

Critical role of endoplasmic reticulum aminopeptidase 1 in determining the length and sequence of peptides bound and presented by HLA-B27. (English)

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8 September 2017

main subject

endoplasmic reticulum

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author

Benedikt M. Kessler

13

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8 September 2017

Tomas Hanke

7

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Nicola Ternette

Nicola Ternette

6

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Roman Fischer

Roman Fischer

2

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Paul Bowness

Paul Bowness

14

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Tim Elliott

Tim Elliott

9

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author name string

Liye Chen

1

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8 September 2017

Yanchun Peng

3

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8 September 2017

Emma Reeves

4

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8 September 2017

Kirsty McHugh

5

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8 September 2017

Tao Dong

8

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8 September 2017

Nilabh Shastri

10

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8 September 2017

Simon Kollnberger

11

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8 September 2017

Edward James

12

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8 September 2017

publication date

1 February 2014

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8 September 2017

published in

Arthritis & Rheumatology

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8 September 2017

volume

66

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8 September 2017

issue

2

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8 September 2017

page(s)

284-294

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Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants

8 September 2017

cites work

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Investigating the genetic association between ERAP1 and ankylosing spondylitis

21 January 2018

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Association of a specific ERAP1/ARTS1 haplotype with disease susceptibility in ankylosing spondylitis

21 January 2018

1 reference

Genetic studies of ankylosing spondylitis in Koreans confirm associations with ERAP1 and 2p15 reported in white patients.

21 January 2018

1 reference

Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility

21 January 2018

1 reference

The ER aminopeptidase ERAP1 enhances or limits antigen presentation by trimming epitopes to 8-9 residues

21 January 2018

1 reference

An IFN-gamma-induced aminopeptidase in the ER, ERAP1, trims precursors to MHC class I-presented peptides

21 January 2018

1 reference

ERAAP customizes peptides for MHC class I molecules in the endoplasmic reticulum

21 January 2018

1 reference

A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1.

21 January 2018

1 reference

Genome-wide association analysis identifies new susceptibility loci for Behçet's disease and epistasis between HLA-B*51 and ERAP1

21 January 2018

1 reference

Endoplasmic reticulum aminopeptidase associated with antigen processing defines the composition and structure of MHC class I peptide repertoire in normal and virus-infected cells

21 January 2018

1 reference

The link between HLA-B27 and SpA--new ideas on an old problem

21 January 2018

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Lymphoblastoid cells express HLA-B27 homodimers both intracellularly and at the cell surface following endosomal recycling.

21 January 2018

1 reference

Direct quantitation of MHC-bound peptide epitopes by selected reaction monitoring

21 January 2018

1 reference

Discovery of candidate serum proteomic and metabolomic biomarkers in ankylosing spondylitis

21 January 2018

1 reference

A cross-platform toolkit for mass spectrometry and proteomics

21 January 2018

1 reference

Differential association of HLA-B*2705 and B*2709 to ankylosing spondylitis correlates with limited peptide subsets but not with altered cell surface stability

21 January 2018

1 reference

HIV-1 gag-specific cytotoxic T lymphocytes defined with recombinant vaccinia virus and synthetic peptides

21 January 2018

1 reference

HLA-B27 homodimers and free H chains are stronger ligands for leukocyte Ig-like receptor B2 than classical HLA class I.

21 January 2018

1 reference

ER aminopeptidases generate a unique pool of peptides for MHC class I molecules.

21 January 2018

1 reference

Rare cell proteomic reactor applied to stable isotope labeling by amino acids in cell culture (SILAC)-based quantitative proteomics study of human embryonic stem cell differentiation.

21 January 2018

1 reference

SILAC-based proteomic analysis to dissect the "histone modification signature" of human breast cancer cells

21 January 2018

1 reference

Comparison of the P2 specificity pocket in three human histocompatibility antigens: HLA-A*6801, HLA-A*0201, and HLA-B*2705.

21 January 2018

1 reference

HLA-B27: a registry of constitutive peptide ligands.

21 January 2018

1 reference

Allele-specific peptide ligand motifs of HLA-C molecules

21 January 2018

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Susceptibility to ankylosing spondylitis correlates with the C-terminal residue of peptides presented by various HLA-B27 subtypes

21 January 2018

1 reference

The specificity of trimming of MHC class I-presented peptides in the endoplasmic reticulum.

21 January 2018

1 reference

Reduced activity of the hypertension-associated Lys528Arg mutant of human adipocyte-derived leucine aminopeptidase (A-LAP)/ER-aminopeptidase-1.

21 January 2018

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Crystal structures of the endoplasmic reticulum aminopeptidase-1 (ERAP1) reveal the molecular basis for N-terminal peptide trimming

21 January 2018

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Cutting Edge: Coding single nucleotide polymorphisms of endoplasmic reticulum aminopeptidase 1 can affect antigenic peptide generation in vitro by influencing basic enzymatic properties of the enzyme

21 January 2018

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Functional interaction of the ankylosing spondylitis-associated endoplasmic reticulum aminopeptidase 1 polymorphism and HLA-B27 in vivo

21 January 2018

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Naturally occurring ERAP1 haplotypes encode functionally distinct alleles with fine substrate specificity.

21 January 2018

1 reference

Analysis of 17 autoimmune disease-associated variants in type 1 diabetes identifies 6q23/TNFAIP3 as a susceptibility locus

21 January 2018

1 reference

Association ofERAP1, but notIL23R, with ankylosing spondylitis in a Han Chinese population

21 January 2018

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Identification of self peptides bound to purified HLA-B27

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/ART.38249

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8 September 2017

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