(Q39031109)

8 September 2017

Thalidomide increases human hepatic cytochrome P450 3A enzymes by direct activation of the pregnane X receptor (English)

1 reference

8 September 2017

0 references

3

1 reference

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2 June 2020

Norio Shibata

5

1 reference

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2 June 2020

Hiroshi Yamazaki

13

1 reference

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2 June 2020

11

F Peter Guengerich

1 reference

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2 June 2020

1

Norie Murayama

1 reference

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Christiane Guguen-Guillouzo

2 June 2020

4

object named as

Christiane Guguen Guillouzo

1 reference

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2 June 2020

7

Masahiro Utoh

1 reference

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2 June 2020

10

Masato Nakamura

1 reference

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2 June 2020

6

Kanako Yajima

1 reference

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2 June 2020

author name string

Rinie van Beuningen

2

1 reference

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2 June 2020

Makiko Shimizu

8

1 reference

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2 June 2020

Christophe Chesné

9

1 reference

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2 June 2020

René Houtman

12

1 reference

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2 June 2020

publication date

5 February 2014

1 reference

Chemical Research in Toxicology

8 September 2017

1 reference

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2 June 2020

volume

27

1 reference

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2 June 2020

issue

2

1 reference

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2 June 2020

page(s)

304-308

1 reference

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Phenobarbital indirectly activates the constitutive active androstane receptor (CAR) by inhibition of epidermal growth factor receptor signaling

2 June 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4020009

In vivo drug interactions of the teratogen thalidomide with midazolam: heterotropic cooperativity of human cytochrome P450 in humanized TK-NOG mice.

9 September 2017

1 reference

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Clinical evidence of pharmacokinetic changes in thalidomide therapy.

9 September 2017

1 reference

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Molecular mechanism of action of immune-modulatory drugs thalidomide, lenalidomide and pomalidomide in multiple myeloma

9 September 2017

1 reference

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In vivo formation of dihydroxylated and glutathione conjugate metabolites derived from thalidomide and 5-Hydroxythalidomide in humanized TK-NOG mice.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4020009

Identification of a primary target of thalidomide teratogenicity

9 September 2017

1 reference

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Thalidomide for treatment of multiple myeloma: 10 years later

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4020009

Thalidomide is an inhibitor of angiogenesis

9 September 2017

1 reference

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Thalidomide teratogenesis: evidence for a toxic arene oxide metabolite

9 September 2017

1 reference

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Free radical-mediated oxidative DNA damage in the mechanism of thalidomide teratogenicity

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4020009

Serine-305 phosphorylation modulates estrogen receptor alpha binding to a coregulator peptide array, with potential application in predicting responses to tamoxifen

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4020009

Synthesis, configurational stability and stereochemical biological evaluations of (S)- and (R)-5-hydroxythalidomides.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4020009

Human cytochrome P450 oxidation of 5-hydroxythalidomide and pomalidomide, an amino analogue of thalidomide

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4020009

Human liver microsomal cytochrome P450 3A enzymes involved in thalidomide 5-hydroxylation and formation of a glutathione conjugate

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4020009

Drug interactions of thalidomide with midazolam and cyclosporine A: heterotropic cooperativity of human cytochrome P450 3A5

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4020009

In vivo formation of a glutathione conjugate derived from thalidomide in humanized uPA-NOG mice

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4020009

Thalidomide as a Possible Biological Acylating Agent

21 August 2018

1 reference

12 December 2020

Effects of oral thalidomide on rat liver and skin microsomal P450 isozyme activities and on urinary porphyrin excretion: interaction with oral hexachlorobenzene

1 reference

12 December 2020

Thalidomide does not alter estrogen-progesterone hormone single dose pharmacokinetics

1 reference

12 December 2020

Thalidomide and congenital abnormalities

1 reference

12 December 2020

Identifiers

DOI

10.1021/TX4004374

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24460184%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24460184%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

PubMed publication ID

24460184

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24460184%20AND%20SRC:MED&resulttype=core&format=json