(Q39037045)

8 September 2017

Neferine attenuates the protein level and toxicity of mutant huntingtin in PC-12 cells via induction of autophagy (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6272412&resulttype=core&format=json

13 May 2020

0 references

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6272412&resulttype=core&format=json

13 May 2020

author name string

An Guo Wu

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6272412&resulttype=core&format=json

13 May 2020

Jing Rong Wang

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6272412&resulttype=core&format=json

13 May 2020

Liang Liu

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6272412&resulttype=core&format=json

13 May 2020

Betty Yuen-Kwan Law

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6272412&resulttype=core&format=json

13 May 2020

language of work or name

English

0 references

publication date

18 February 2015

1 reference

8 September 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6272412&resulttype=core&format=json

13 May 2020

volume

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6272412&resulttype=core&format=json

13 May 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6272412&resulttype=core&format=json

13 May 2020

page(s)

3496-3514

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6272412&resulttype=core&format=json

Creative Commons Attribution 4.0 International

13 May 2020

copyright license

start time

18 February 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6272412/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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Autophagy gone awry in neurodegenerative diseases

21 January 2018

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SQSTM1 mutations in familial and sporadic amyotrophic lateral sclerosis

21 January 2018

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α-Synuclein impairs macroautophagy: implications for Parkinson's disease.

21 January 2018

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Regulation of intracellular accumulation of mutant Huntingtin by Beclin 1

21 January 2018

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Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease

21 January 2018

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The role of autophagy in neurodegenerative disease

21 January 2018

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Aggregate-prone proteins with polyglutamine and polyalanine expansions are degraded by autophagy

21 January 2018

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Rilmenidine attenuates toxicity of polyglutamine expansions in a mouse model of Huntington's disease

21 January 2018

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Small molecules enhance autophagy and reduce toxicity in Huntington's disease models.

21 January 2018

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Lessons from animal models of Huntington's disease

21 January 2018

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Fisetin induces autophagic cell death through suppression of mTOR signaling pathway in prostate cancer cells

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Potential therapeutic applications of autophagy

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Adverse events associated with mTOR inhibitors

21 January 2018

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Synergistic effect of hyperthermia and neferine on reverse multidrug resistance in adriamycin-resistant SGC7901/ADM gastric cancer cells

21 January 2018

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Neferine from Nelumbo nucifera induces autophagy through the inhibition of PI3K/Akt/mTOR pathway and ROS hyper generation in A549 cells.

21 January 2018

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Anti-amnesic activity of neferine with antioxidant and anti-inflammatory capacities, as well as inhibition of ChEs and BACE1.

21 January 2018

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Guidelines for the use and interpretation of assays for monitoring autophagy

21 January 2018

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Saikosaponin-d, a novel SERCA inhibitor, induces autophagic cell death in apoptosis-defective cells.

21 January 2018

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Dual role of 3-methyladenine in modulation of autophagy via different temporal patterns of inhibition on class I and III phosphoinositide 3-kinase

21 January 2018

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Lysosomal turnover, but not a cellular level, of endogenous LC3 is a marker for autophagy

21 January 2018

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Alisol B, a novel inhibitor of the sarcoplasmic/endoplasmic reticulum Ca(2+) ATPase pump, induces autophagy, endoplasmic reticulum stress, and apoptosis

21 January 2018

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Natural small-molecule enhancers of autophagy induce autophagic cell death in apoptosis-defective cells.

21 January 2018

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Monitoring autophagic degradation of p62/SQSTM1.

21 January 2018

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AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

21 January 2018

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Protein turnover via autophagy: implications for metabolism

21 January 2018

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Deciphering downstream gene targets of PI3K/mTOR/p70S6K pathway in breast cancer

21 January 2018

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Ageing, neurodegeneration and Parkinson's disease

21 January 2018

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The roles of intracellular protein-degradation pathways in neurodegeneration

21 January 2018

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The Three Musketeers of Autophagy: phosphorylation, ubiquitylation and acetylation

21 January 2018

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Onjisaponin B derived from Radix Polygalae enhances autophagy and accelerates the degradation of mutant α-synuclein and huntingtin in PC-12 cells

21 January 2018

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Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice

21 January 2018

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Trehalose, a novel mTOR-independent autophagy enhancer, accelerates the clearance of mutant huntingtin and alpha-synuclein.

21 January 2018

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A molecular investigation of true dominance in Huntington's disease

21 January 2018

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α-Synuclein Is Degraded by Both Autophagy and the Proteasome

21 January 2018

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Autophagy and its possible roles in nervous system diseases, damage and repair

21 January 2018

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Chemical inducers of autophagy that enhance the clearance of mutant proteins in neurodegenerative diseases.

21 January 2018

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Inositol hexakisphosphate kinases induce cell death in Huntington disease

21 January 2018

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Inositol hexakisphosphate kinases promote autophagy.

21 January 2018

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Repeat-associated non-ATG (RAN) translation in neurological disease

21 January 2018

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Myotonic dystrophy type 2 caused by a CCTG expansion in intron 1 of ZNF9

21 January 2018

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Traditional Chinese medicine: a promising candidate for the treatment of Alzheimer's disease

21 January 2018

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Neuroprotective effects of salidroside against beta-amyloid-induced oxidative stress in SH-SY5Y human neuroblastoma cells

21 January 2018

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Curcumin inhibits formation of amyloid beta oligomers and fibrils, binds plaques, and reduces amyloid in vivo

21 January 2018

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Huperzine A, a potential therapeutic agent for dementia, reduces neuronal cell death caused by glutamate.

21 January 2018

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Protective effect of neferine on endothelial cell nitric oxide production induced by lysophosphatidylcholine: the role of the DDAH-ADMA pathway

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25699594

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.3390/MOLECULES20033496

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6272412&resulttype=core&format=json

13 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6272412&resulttype=core&format=json

13 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6272412&resulttype=core&format=json