(Q39042781)

8 September 2017

The Rho GTPase Rac1 is required for recycling endosome-mediated secretion of TNF in macrophages (English)

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8 September 2017

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Tatiana Khromykh

5

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Paige Lacy

object named as

Paige Lacy

7

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Jennifer Stow

object named as

Jennifer L Stow

6

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author name string

Amanda C Stanley

1

1 reference

8 September 2017

Colin X Wong

2

1 reference

8 September 2017

Massimo Micaroni

3

1 reference

8 September 2017

Juliana Venturato

4

1 reference

8 September 2017

language of work or name

1 reference

17 December 2013

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Immunology & Cell Biology

8 September 2017

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8 September 2017

92

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8 September 2017

3

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8 September 2017

275-286

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https://scigraph.springernature.com/pub.10.1038/icb.2013.90

8 September 2017

0 references

cites work

Resolution of inflammation: the beginning programs the end

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.90

Differentiation and heterogeneity in the mononuclear phagocyte system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.90

Protective and pathogenic functions of macrophage subsets

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.90

Cytokine release from innate immune cells: association with diverse membrane trafficking pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.90

A calculated response: control of inflammation by the innate immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.90

Origin and physiological roles of inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.90

TNF-mediated inflammatory disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.90

Syntaxin 6 and Vti1b form a novel SNARE complex, which is up-regulated in activated macrophages to facilitate exocytosis of tumor necrosis Factor-alpha.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.90

Subcompartments of the macrophage recycling endosome direct the differential secretion of IL-6 and TNFalpha.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.90

Cytokine secretion via cholesterol-rich lipid raft-associated SNAREs at the phagocytic cup.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.90

Historical overview of Rho GTPases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.90

Mammalian Rho GTPases: new insights into their functions from in vivo studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.90

Regulation of innate immunity by Rho GTPases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.90

Cdc42 localization and cell polarity depend on membrane traffic

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.90

Rho GTPases and exocytosis: what are the molecular links?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.90

Function of Rho family proteins in actin dynamics during phagocytosis and engulfment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.90

Actin dynamics during phagocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.90

Cdc42 controls secretory and endocytic transport to the basolateral plasma membrane of MDCK cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.90

Spatio-temporal regulation of Rac1 and Cdc42 activity during nerve growth factor-induced neurite outgrowth in PC12 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.90

Cdc42 and Rac stimulate exocytosis of secretory granules by activating the IP(3)/calcium pathway in RBL-2H3 mast cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.90

Polarized trafficking of E-cadherin is regulated by Rac1 and Cdc42 in Madin-Darby canine kidney cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.90

Rac2 is critical for neutrophil primary granule exocytosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.90

Protein complexes containing CYFIP/Sra/PIR121 coordinate Arf1 and Rac1 signalling during clathrin-AP-1-coated carrier biogenesis at the TGN.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.90

Bridging membrane and cytoskeleton dynamics in the secretory and endocytic pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.90

Requirements for both Rac1 and Cdc42 in membrane ruffling and phagocytosis in leukocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.90

Localization and post-Golgi trafficking of tumor necrosis factor-alpha in macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.90

Rac1 is required for the formation of three germ layers during gastrulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.90

Specificity and mechanism of action of EHT 1864, a novel small molecule inhibitor of Rac family small GTPases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.90

Rational design and characterization of a Rac GTPase-specific small molecule inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.90

Rac2-deficient murine macrophages have selective defects in superoxide production and phagocytosis of opsonized particles

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.90

Deficiency of the hematopoietic cell-specific Rho family GTPase Rac2 is characterized by abnormalities in neutrophil function and host defense

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.90

Agonist activation of f-actin-mediated eosinophil shape change and mediator release is dependent on Rac2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.90

Lipopolysaccharide induces Rac1-dependent reactive oxygen species formation and coordinates tumor necrosis factor-alpha secretion through IKK regulation of NF-kappa B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.90

Ligands of macrophage scavenger receptor induce cytokine expression via differential modulation of protein kinase signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.90

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.90

Rho GTPases in cell biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.90

Filopodia: molecular architecture and cellular functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.90

Regulation of NADPH oxidases: the role of Rac proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.90

Rho GTPases and regulation of hematopoietic stem cell localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.90

Moving mitochondria: establishing distribution of an essential organelle

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.90

Cytoplasmic intermediate filaments mediate actin-driven positioning of the nucleus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.90

Membrane trafficking, organelle transport, and the cytoskeleton.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.90

Actin dynamics is essential for myosin-based transport of membrane organelles

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.90

The role of myosin V in exocytosis and synaptic plasticity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.90

Regulation of endocytic traffic by rho family GTPases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.90

RhoD regulates endosome dynamics through Diaphanous-related Formin and Src tyrosine kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.90

RhoD, Src, and hDia2C in endosome motility

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.90

Rab and actomyosin-dependent fission of transport vesicles at the Golgi complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.90

A role for Rac in Tiam1-induced membrane ruffling and invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.90

Rac1, a low-molecular-mass GTP-binding-protein with high intrinsic GTPase activity and distinct biochemical properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.90

Guanine nucleotide binding properties of Rac2 mutant proteins and analysis of the responsiveness to guanine nucleotide dissociation stimulator

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.90

Rho GTPases and their effector proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.90

Molecular basis for Rho GTPase signaling specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.90

The Rho family GTPase Rif induces filopodia through mDia2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.90

Cdc42 is not essential for filopodium formation, directed migration, cell polarization, and mitosis in fibroblastoid cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.90

The t-SNARE syntaxin 4 is regulated during macrophage activation to function in membrane traffic and cytokine secretion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.90

VAMP3 regulates podosome organisation in macrophages and together with Stx4/SNAP23 mediates adhesion, cell spreading and persistent migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.90

Rac1 and Rac2 regulate macrophage morphology but are not essential for migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.90

Rac GTPases differentially integrate signals regulating hematopoietic stem cell localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.90

inferred from DOI database lookup

7 January 2021

based on heuristic

Hematopoietic Cell Regulation by Rac1 and Rac2 Guanosine Triphosphatases

1 reference

https://api.crossref.org/works/10.1038%2FICB.2013.90

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/ICB.2013.90

1 reference

Dimensions Publication ID

8 September 2017

0 references

1 reference