(Q39061982)

English

Vascular immunotargeting to endothelial determinant ICAM-1 enables optimal partnering of recombinant scFv-thrombomodulin fusion with endogenous cofactor

scientific article published on 14 November 2013

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scholarly article

1 reference

Europe PubMed Central

8 September 2017

Vascular immunotargeting to endothelial determinant ICAM-1 enables optimal partnering of recombinant scFv-thrombomodulin fusion with endogenous cofactor (English)

1 reference

Europe PubMed Central

8 September 2017

0 references

Ann-marie Chacko

object named as

Ann-Marie Chacko

2

0 references

Colin F Greineder

object named as

Colin F Greineder

1

0 references

author name string

Sergei Zaytsev

3

1 reference

Europe PubMed Central

8 September 2017

Blaine J Zern

4

1 reference

Europe PubMed Central

8 September 2017

Ronald Carnemolla

5

1 reference

Europe PubMed Central

8 September 2017

Elizabeth D Hood

6

1 reference

Europe PubMed Central

8 September 2017

Jingyan Han

7

1 reference

Europe PubMed Central

8 September 2017

Bi-Sen Ding

8

1 reference

Europe PubMed Central

8 September 2017

Charles T Esmon

9

1 reference

Europe PubMed Central

8 September 2017

Vladimir R Muzykantov

10

1 reference

Europe PubMed Central

8 September 2017

language of work or name

0 references

publication date

14 November 2013

1 reference

Europe PubMed Central

8 September 2017

1 reference

Europe PubMed Central

8 September 2017

8

1 reference

Europe PubMed Central

8 September 2017

11

1 reference

Europe PubMed Central

8 September 2017

e80110

1 reference

Europe PubMed Central

8 September 2017

copyright license

Creative Commons Attribution 4.0 International

14 November 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

Collaborative enhancement of antibody binding to distinct PECAM-1 epitopes modulates endothelial targeting

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3828233

9 September 2017

Targeted siRNA delivery to diseased microvascular endothelial cells: cellular and molecular concepts.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3828233

9 September 2017

The thrombomodulin analog Solulin promotes reperfusion and reduces infarct volume in a thrombotic stroke model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3828233

9 September 2017

Inside-out regulation of ICAM-1 dynamics in TNF-alpha-activated endothelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3828233

9 September 2017

Anchoring fusion thrombomodulin to the endothelial lumen protects against injury-induced lung thrombosis and inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3828233

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Adverse outcomes associated with the use of drotrecogin alfa (activated) in patients with severe sepsis and baseline bleeding precautions

1 reference

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Post-cardiac arrest syndrome: epidemiology, pathophysiology, treatment, and prognostication. A consensus statement from the International Liaison Committee on Resuscitation (American Heart Association, Australian and New Zealand Council on Resuscita

1 reference

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9 September 2017

The coagulation system and pulmonary endothelial function in acute lung injury

1 reference

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9 September 2017

Targeted delivery of therapeutics to endothelium

1 reference

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9 September 2017

Randomized clinical trial of activated protein C for the treatment of acute lung injury

1 reference

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9 September 2017

Evolving functions of endothelial cells in inflammation

1 reference

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9 September 2017

Endotoxemia and sepsis mortality reduction by non-anticoagulant activated protein C.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3828233

9 September 2017

Receptors of the protein C activation and activated protein C signaling pathways are colocalized in lipid rafts of endothelial cells

1 reference

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9 September 2017

Recent approaches to intracellular delivery of drugs and DNA and organelle targeting

1 reference

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9 September 2017

Biomedical aspects of targeted delivery of drugs to pulmonary endothelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3828233

9 September 2017

Endothelial barrier protection by activated protein C through PAR1-dependent sphingosine 1-phosphate receptor-1 crossactivation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3828233

9 September 2017

Thrombomodulin-protein C-EPCR system: integrated to regulate coagulation and inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3828233

9 September 2017

The role of the endothelium in severe sepsis and multiple organ dysfunction syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3828233

9 September 2017

Vascular immunotargeting of glucose oxidase to the endothelial antigens induces distinct forms of oxidant acute lung injury: targeting to thrombomodulin, but not to PECAM-1, causes pulmonary thrombosis and neutrophil transmigration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3828233

9 September 2017

Down-regulation of endothelial expression of endothelial cell protein C receptor and thrombomodulin in coronary atherosclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3828233

9 September 2017

The normal role of Activated Protein C in maintaining homeostasis and its relevance to critical illness

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3828233

9 September 2017

Efficacy and safety of recombinant human activated protein C for severe sepsis

1 reference

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9 September 2017

Aminopeptidase N is a receptor for tumor-homing peptides and a target for inhibiting angiogenesis

1 reference

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9 September 2017

Targets for gene therapy of vein grafts

1 reference

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9 September 2017

The biology of PECAM-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3828233

9 September 2017

The endothelial cell protein C receptor augments protein C activation by the thrombin-thrombomodulin complex.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3828233

9 September 2017

Molecular cloning and expression of murine and bovine endothelial cell protein C/activated protein C receptor (EPCR). The structural and functional conservation in human, bovine, and murine EPCR

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3828233

9 September 2017

Interleukin 1 induces endothelial cell procoagulant while suppressing cell-surface anticoagulant activity

1 reference

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Protein C prevents the coagulopathic and lethal effects of Escherichia coli infusion in the baboon

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3828233

9 September 2017

The roles of protein C and thrombomodulin in the regulation of blood coagulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3828233

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The arrangement of the immunoglobulin-like domains of ICAM-1 and the binding sites for LFA-1 and rhinovirus

1 reference

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9 September 2017

Molecular and cellular properties of PECAM-1 (endoCAM/CD31): a novel vascular cell-cell adhesion molecule

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3828233

9 September 2017

Lung vascular targeting using antibody to aminopeptidase P: CT-SPECT imaging, biodistribution and pharmacokinetic analysis.

1 reference

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14 September 2017

A novel endocytic pathway induced by clustering endothelial ICAM-1 or PECAM-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3828233

14 September 2017

The role of PECAM-1 in vascular cell biology

1 reference

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14 September 2017

Nucleotide sequence of Y3-Ag 1.2.3. rat myeloma immunoglobulin kappa chain cDNA.

1 reference

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14 September 2017

Oxidation of a specific methionine in thrombomodulin by activated neutrophil products blocks cofactor activity. A potential rapid mechanism for modulation of coagulation

1 reference

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PLGA nanoparticle--peptide conjugate effectively targets intercellular cell-adhesion molecule-1.

1 reference

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1 reference

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Overexpressing endothelial cell protein C receptor alters the hemostatic balance and protects mice from endotoxin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3828233

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Non-viral in vivo thrombomodulin gene transfer prevents early loss of thromboresistance of grafted veins

1 reference

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Dysfunction of Endothelial Protein C Activation in Severe Meningococcal Sepsis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3828233

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Internalization of the anticoagulant thrombomodulin is constitutive and does not require a signal in the cytoplasmic domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3828233

2 December 2018

Lung uptake of antibodies to endothelial antigens: key determinants of vascular immunotargeting

1 reference

https://pubmed.ncbi.nlm.nih.gov/24244621

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of a mouse model for thrombomodulin deficiency

1 reference

https://pubmed.ncbi.nlm.nih.gov/24244621

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Early loss of thrombomodulin expression impairs vein graft thromboresistance: implications for vein graft failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/24244621

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serum thrombomodulin level relates to the clinical course of disseminated intravascular coagulation, multiorgan dysfunction syndrome, and mortality in patients with sepsis

1 reference

https://pubmed.ncbi.nlm.nih.gov/24244621

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endothelial endocytic pathways: gates for vascular drug delivery

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https://pubmed.ncbi.nlm.nih.gov/24244621

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Isolation of IgG antibody Fv-DNA from various mouse and rat hybridoma cell lines using the polymerase chain reaction with a simple set of primers

1 reference

https://pubmed.ncbi.nlm.nih.gov/24244621

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Soluble thrombomodulin--a marker of reperfusion injury after orthotopic liver transplantation

1 reference

https://pubmed.ncbi.nlm.nih.gov/24244621

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inferred from PubMed ID database lookup

Modulation of human endothelial thrombomodulin by neutrophils and their release products

1 reference

https://pubmed.ncbi.nlm.nih.gov/24244621

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Local overexpression of thrombomodulin for in vivo prevention of arterial thrombosis in a rabbit model

1 reference

https://pubmed.ncbi.nlm.nih.gov/24244621

12 December 2020

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inferred from PubMed ID database lookup

Coagulopathy after successful cardiopulmonary resuscitation following cardiac arrest: implication of the protein C anticoagulant pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/24244621

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Efficacy and safety of recombinant human soluble thrombomodulin (ART-123) in disseminated intravascular coagulation: results of a phase III, randomized, double-blind clinical trial

1 reference

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Identifiers

10.1371/JOURNAL.PONE.0080110

1 reference

Europe PubMed Central

8 September 2017

2013PLoSO...880110G

0 references

1 reference

Europe PubMed Central

8 September 2017

1 reference

Europe PubMed Central

8 September 2017

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