(Q39073113)

8 September 2017

title

Involvement and targeted intervention of dysregulated Hedgehog signaling in osteosarcoma (English)

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8 September 2017

7

Irene L Andrulis

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8 September 2017

Winnie W Lo

1

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8 September 2017

Jay S Wunder

2

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8 September 2017

Brendan C Dickson

3

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8 September 2017

Veronica Campbell

4

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8 September 2017

Karen McGovern

5

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8 September 2017

Benjamin A Alman

6

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8 September 2017

language of work or name

English

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publication date

21 October 2013

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8 September 2017

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8 September 2017

volume

120

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8 September 2017

issue

4

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8 September 2017

page(s)

537-547

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Mechanisms and functions of Hedgehog signalling across the metazoa

8 September 2017

cites work

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https://api.crossref.org/works/10.1002%2FCNCR.28439

Hedgehog signaling in development and cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.28439

Indian hedgehog signaling regulates proliferation and differentiation of chondrocytes and is essential for bone formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.28439

Hedgehog signaling in skeletal development

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.28439

Efficacy and safety of vismodegib in advanced basal-cell carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.28439

Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.28439

Purmorphamine activates the Hedgehog pathway by targeting Smoothened.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.28439

Inhibition of GLI-mediated transcription and tumor cell growth by small-molecule antagonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.28439

Small molecule modulation of Smoothened activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.28439

Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.28439

Discovery of a potent and orally active hedgehog pathway antagonist (IPI-926)

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.28439

Self-renewal of acute lymphocytic leukemia cells is limited by the Hedgehog pathway inhibitors cyclopamine and IPI-926

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.28439

Inhibition of Hedgehog signaling antagonizes serous ovarian cancer growth in a primary xenograft model

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.28439

Hedgehog pathway inhibitor saridegib (IPI-926) increases lifespan in a mouse medulloblastoma model

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.28439

A paracrine requirement for hedgehog signalling in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.28439

Hedgehog signaling promotes prostate xenograft tumor growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.28439

Hedgehog signaling is restricted to the stromal compartment during pancreatic carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.28439

Altered expression and deletion of RMO1 in osteosarcoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.28439

The Hedgehog's tale: developing strategies for targeting cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.28439

Mechanisms of Hedgehog pathway activation in cancer and implications for therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.28439

Context-dependent regulation of the GLI code in cancer by HEDGEHOG and non-HEDGEHOG signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.28439

Dose- and route-dependent teratogenicity, toxicity, and pharmacokinetic profiles of the hedgehog signaling antagonist cyclopamine in the mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.28439

Regulation of rate of cartilage differentiation by Indian hedgehog and PTH-related protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.28439

Hedgehog regulates cell growth and proliferation by inducing Cyclin D and Cyclin E.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.28439

Inhibition of neuroepithelial patched-induced apoptosis by sonic hedgehog

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.28439

Inhibition of osteosarcoma cell proliferation by the Hedgehog-inhibitor cyclopamine

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.28439

Smoothened as a new therapeutic target for human osteosarcoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.28439

Role of GLI2 in the growth of human osteosarcoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.28439

Targeting hedgehog-GLI-2 pathway in osteosarcoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.28439

The activities of Smad and Gli mediated signalling pathways in high-grade conventional osteosarcoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.28439

Essential role of stromally induced hedgehog signaling in B-cell malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.28439

Hedgehog-induced survival of B-cell chronic lymphocytic leukemia cells in a stromal cell microenvironment: a potential new therapeutic target

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.28439

Crosstalk between TGF-β and hedgehog signaling in cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCNCR.28439

21 January 2018

Identifiers

DOI

10.1002/CNCR.28439

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8 September 2017

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