(Q39093841)

https://doi.org/10.1007/s10495-024-01951-8

9 September 2017

1 reference

14 April 2024

title

Mahanine synergistically enhances cytotoxicity of 5-fluorouracil through ROS-mediated activation of PTEN and p53/p73 in colon carcinoma (English)

1 reference

9 September 2017

0 references

1 reference

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24052409%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

author name string

Ranjita Das

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24052409%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

Kaushik Bhattacharya

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24052409%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

Sayantani Sarkar

3

1 reference

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14 June 2020

Bikas C Pal

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24052409%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

Chitra Mandal

6

1 reference

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14 June 2020

publication date

1 January 2014

1 reference

9 September 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24052409%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

volume

19

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14 June 2020

issue

1

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14 June 2020

page(s)

149-164

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https://scigraph.springernature.com/pub.10.1007/s10495-013-0907-6

14 June 2020

exact match

0 references

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p73 tumor suppressor protein: a close relative of p53 not only in structure but also in anti-cancer approach?

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21 January 2018

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P38MAPK is a major determinant of the balance between apoptosis and autophagy triggered by 5-fluorouracil: implication in resistance

21 January 2018

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Pharmacogenetic profiling in patients with advanced colorectal cancer treated with first-line FOLFIRI chemotherapy

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Violacein synergistically increases 5-fluorouracil cytotoxicity, induces apoptosis and inhibits Akt-mediated signal transduction in human colorectal cancer cells

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Antimutagenicity of some edible Thai plants, and a bioactive carbazole alkaloid, mahanine, isolated from Micromelum minutum

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Induction of apoptosis by carbazole alkaloids isolated from Murraya koenigii

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Mechanism of mahanine-induced apoptosis in human leukemia cells (HL-60).

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Mahanine inhibits growth and induces apoptosis in prostate cancer cells through the deactivation of Akt and activation of caspases

21 January 2018

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Mahanine, a carbazole alkaloid from Micromelum minutum, inhibits cell growth and induces apoptosis in U937 cells through a mitochondrial dependent pathway

21 January 2018

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Apoptotic effects of mahanine on human leukemic cells are mediated through crosstalk between Apo-1/Fas signaling and the Bid protein and via mitochondrial pathways

21 January 2018

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Oxidative inhibition of Hsp90 disrupts the super-chaperone complex and attenuates pancreatic adenocarcinoma in vitro and in vivo.

21 January 2018

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Mahanine, a DNA minor groove binding agent exerts cellular cytotoxicity with involvement of C-7-OH and -NH functional groups.

21 January 2018

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Mahanine reverses an epigenetically silenced tumor suppressor gene RASSF1A in human prostate cancer cells

21 January 2018

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Withaferin A induces apoptosis by activating p38 mitogen-activated protein kinase signaling cascade in leukemic cells of lymphoid and myeloid origin through mitochondrial death cascade.

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5-Fluorouracil induced intestinal mucositis via nuclear factor-κB activation by transcriptomic analysis and in vivo bioluminescence imaging

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Cellular response to 5-fluorouracil (5-FU) in 5-FU-resistant colon cancer cell lines during treatment and recovery

21 January 2018

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p53 inactivation upregulates p73 expression through E2F-1 mediated transcription

21 January 2018

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PTEN nuclear localization is regulated by oxidative stress and mediates p53-dependent tumor suppression

21 January 2018

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HDM2 antagonist Nutlin-3 disrupts p73-HDM2 binding and enhances p73 function.

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21 January 2018

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21 January 2018

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Combination of 5-fluorouracil and genistein induces apoptosis synergistically in chemo-resistant cancer cells through the modulation of AMPK and COX-2 signaling pathways

21 January 2018

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Notoginseng enhances anti-cancer effect of 5-fluorouracil on human colorectal cancer cells

21 January 2018

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21 January 2018

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21 January 2018

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PTEN and p53 cross-regulation induced by soy isoflavone genistein promotes mammary epithelial cell cycle arrest and lobuloalveolar differentiation

21 January 2018

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21 January 2018

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21 January 2018

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10.1007/S10495-013-0907-6

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24052409%20AND%20SRC:MED&resulttype=core&format=json

14 June 2020

1 reference