(Q39490275)

https://doi.org/10.1038/s41388-024-02963-z

12 September 2017

1 reference

14 April 2024

title

P38MAPK is a major determinant of the balance between apoptosis and autophagy triggered by 5-fluorouracil: implication in resistance (English)

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12 September 2017

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M A de la Cruz-Morcillo

1

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12 September 2017

M L L Valero

2

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12 September 2017

J L Callejas-Valera

3

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12 September 2017

L Arias-González

4

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12 September 2017

P Melgar-Rojas

5

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12 September 2017

E M Galán-Moya

6

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12 September 2017

E García-Gil

7

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12 September 2017

J García-Cano

8

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12 September 2017

R Sánchez-Prieto

9

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12 September 2017

language of work or name

English

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publication date

15 August 2011

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12 September 2017

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12 September 2017

volume

31

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12 September 2017

issue

9

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12 September 2017

page(s)

1073-1085

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https://scigraph.springernature.com/pub.10.1038/onc.2011.321

12 September 2017

exact match

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cites work

DNA damage sensors ATM, ATR, DNA-PKcs, and PARP-1 are dispensable for human immunodeficiency virus type 1 integration

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Modulation of intracellular ROS levels by TIGAR controls autophagy

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Mechanism of p38 MAP kinase activation in vivo.

21 January 2018

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Phosphorylation of human p53 by p38 kinase coordinates N-terminal phosphorylation and apoptosis in response to UV radiation

21 January 2018

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Requirement for p53 and p21 to sustain G2 arrest after DNA damage

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Disruption of p53 in human cancer cells alters the responses to therapeutic agents

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E1a gene expression blocks the ERK1/2 signaling pathway by promoting nuclear localization and MKP up-regulation: implication in v-H-Ras-induced senescence

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Capecitabine and vinorelbine in metastatic breast cancer

21 January 2018

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A novel cell type-specific role of p38α in the control of autophagy and cell death in colorectal cancer cells

21 January 2018

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ATR and ATRIP: partners in checkpoint signaling

21 January 2018

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p73 regulates DRAM-independent autophagy that does not contribute to programmed cell death

21 January 2018

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DRAM, a p53-induced modulator of autophagy, is critical for apoptosis

21 January 2018

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A new p38 MAP kinase-regulated transcriptional coactivator that stimulates p53-dependent apoptosis

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Mechanisms and functions of p38 MAPK signalling.

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p53 post-translational modification: deregulated in tumorigenesis

21 January 2018

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Inhibition of p38 MAPK suppresses inflammatory cytokine induction by etoposide, 5-fluorouracil, and doxorubicin without affecting tumoricidal activity

21 January 2018

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ATM and the Mre11-Rad50-Nbs1 complex respond to nucleoside analogue-induced stalled replication forks and contribute to drug resistance

21 January 2018

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Nucleoside analogs: molecular mechanisms signaling cell death.

21 January 2018

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Loss of atm sensitises p53-deficient cells to topoisomerase poisons and antimetabolites

21 January 2018

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c-Abl activates p38 MAPK independently of its tyrosine kinase activity: Implications in cisplatin-based therapy.

21 January 2018

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Activation of the novel stress-activated protein kinase SAPK4 by cytokines and cellular stresses is mediated by SKK3 (MKK6); comparison of its substrate specificity with that of other SAP kinases

21 January 2018

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Cytoplasmic functions of the tumour suppressor p53.

21 January 2018

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Involvement of p38 mitogen-activated protein kinase in gemcitabine-induced apoptosis in human pancreatic cancer cells

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ATR-dependent activation of p38 MAP kinase is responsible for apoptotic cell death in cells depleted of Cdc7.

21 January 2018

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Reduced ATR or Chk1 expression leads to chromosome instability and chemosensitization of mismatch repair-deficient colorectal cancer cells

21 January 2018

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LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

21 January 2018

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Regulation of p53 stability and function in HCT116 colon cancer cells

21 January 2018

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Autophagy and the integrated stress response

21 January 2018

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p38 Mitogen-activated protein kinase- and HuR-dependent stabilization of p21(Cip1) mRNA mediates the G(1)/S checkpoint

21 January 2018

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Suppression of HIV-1 infection by a small molecule inhibitor of the ATM kinase

21 January 2018

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Inhibition of autophagy augments 5-fluorouracil chemotherapy in human colon cancer in vitro and in vivo model

21 January 2018

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Inhibition of autophagy by 3-MA enhances the effect of 5-FU-induced apoptosis in colon cancer cells

21 January 2018

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The ATM inhibitor KU-55933 suppresses cell proliferation and induces apoptosis by blocking Akt in cancer cells with overactivated Akt.

21 January 2018

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The mismatch repair-mediated cell cycle checkpoint response to fluorodeoxyuridine

21 January 2018

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5-Fluorouracil: mechanisms of action and clinical strategies

21 January 2018

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Role of the p38 MAPK pathway in cisplatin-based therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.321

p53-dependent apoptosis modulates the cytotoxicity of anticancer agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.321

Autophagy regulation by p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.321

Stimulation of autophagy by the p53 target gene Sestrin2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.321

p38 MAPK links oxidative stress to autophagy-related gene expression in cachectic muscle wasting

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.321

Inhibition of phosphatidylinositol 3-kinase promotes tumor cell resistance to chemotherapeutic agents via a mechanism involving delay in cell cycle progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.321

Autophagy in mammalian development and differentiation

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2011.321

The mutational status of p53 protein in gastric and esophageal adenocarcinoma cell lines predicts sensitivity to chemotherapeutic agents

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2011.321

Induction of autophagy by drug-resistant esophageal cancer cells promotes their survival and recovery following treatment with chemotherapeutics

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2011.321

p38 MAP kinase: a convergence point in cancer therapy

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2011.321

Critical involvement of the ATM-dependent DNA damage response in the apoptotic demise of HIV-1-elicited syncytia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.321

Induction of thymidylate synthase as a 5-fluorouracil resistance mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.321

Colon cancer in older adults

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.321

p53-deficient cells rely on ATM- and ATR-mediated checkpoint signaling through the p38MAPK/MK2 pathway for survival after DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.321

DNA damage activates a spatially distinct late cytoplasmic cell-cycle checkpoint network controlled by MK2-mediated RNA stabilization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.321

Modulation of the p38 MAPK (mitogen-activated protein kinase) pathway through Bcr/Abl: implications in the cellular response to Ara-C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.321

Regulation of p73 by c-Abl through the p38 MAP kinase pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.321

Advances in the systemic treatment of head and neck cancers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.321

A dual role of p53 in the control of autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.321

Regulation of autophagy by cytoplasmic p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.321

Full activation of PKB/Akt in response to insulin or ionizing radiation is mediated through ATM.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.321

Signal integration by JNK and p38 MAPK pathways in cancer development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.321

Coordinated regulation of autophagy by p38alpha MAPK through mAtg9 and p38IP

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.321

Loss of ataxia telangiectasia mutated- and Rad3-related function potentiates the effects of chemotherapeutic drugs on cancer cell survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.321

Participation of DNA repair in the response to 5-fluorouracil

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.321

Autophagic cell death induced by 5-FU in Bax or PUMA deficient human colon cancer cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.321

BNIP3 is essential for mediating 6-thioguanine- and 5-fluorouracil-induced autophagy following DNA mismatch repair processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.321

Molecular basis for the induction of an angiogenesis inhibitor, thrombospondin-1, by 5-fluorouracil

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.321

The influence of the p53 gene on the in vitro chemosensitivity of colorectal cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.321

Consideration about negative controls for LC3 and expression vectors for four colored fluorescent protein-LC3 negative controls

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.321

Survival of colorectal cancer cell lines treated with paclitaxel, radiation, and 5-FU: effect of TP53 or hMLH1 deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.321

31 March 2020

Identifiers

DOI

10.1038/ONC.2011.321

1 reference

release_4enjxqfz2zgv7i7nyivdr773bu

12 September 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/4enjxqfz2zgv7i7nyivdr773bu

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference