(Q39106369)

9 September 2017

Complex oncogenic translocations with gene amplification are initiated by specific DNA breaks in lymphocytes (English)

1 reference

9 September 2017

Sarah M Wright

1

1 reference

9 September 2017

Yong H Woo

2

1 reference

9 September 2017

Travis L Alley

3

1 reference

9 September 2017

Bobbi-Jo Shirley

4

1 reference

9 September 2017

Ellen C Akeson

5

1 reference

9 September 2017

Kathy J Snow

6

1 reference

9 September 2017

Sarah A Maas

7

1 reference

9 September 2017

Rachel L Elwell

8

1 reference

9 September 2017

Oded Foreman

9

1 reference

9 September 2017

Kevin D Mills

10

1 reference

9 September 2017

language of work or name

English

0 references

publication date

12 May 2009

1 reference

9 September 2017

1 reference

9 September 2017

69

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9 September 2017

10

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9 September 2017

4454-4460

1 reference

Lymphocyte-specific compensation for XLF/cernunnos end-joining functions in V(D)J recombination

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724672

Requirement for enhancer specificity in immunoglobulin heavy chain locus regulation

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724672

Multiple, conserved cryptic recombination signals in VH gene segments: detection of cleavage products only in pro B cells

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724672

In a model of immunoglobulin heavy-chain (IGH)/MYC translocation, the Igh 3' regulatory region induces MYC expression at the immature stage of B cell development

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724672

Amplification of IGH/MYC fusion in clinically aggressive IGH/BCL2-positive germinal center B-cell lymphomas.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724672

Regulation of immunoglobulin heavy-chain gene rearrangements

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724672

The role of the non-homologous end-joining pathway in lymphocyte development

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724672

Artemis and p53 cooperate to suppress oncogenic N-myc amplification in progenitor B cells.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724672

Artemis, a novel guardian of the genome

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724672

The role of DNA breaks in genomic instability and tumorigenesis

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724672

Defective DNA repair and increased genomic instability in Artemis-deficient murine cells

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724672

Take care of your chromosomes lest cancer take care of you.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724672

Leaky Scid phenotype associated with defective V(D)J coding end processing in Artemis-deficient mice

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724672

Evidence for replicative repair of DNA double-strand breaks leading to oncogenic translocation and gene amplification

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724672

The mechanism and regulation of chromosomal V(D)J recombination

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724672

Does artemis end the hunt for the hairpin-opening activity in V(D)J recombination?

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724672

Ts65Dn -- localization of the translocation breakpoint and trisomic gene content in a mouse model for Down syndrome

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724672

Artemis, a novel DNA double-strand break repair/V(D)J recombination protein, is mutated in human severe combined immune deficiency.

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724672

Differential requirements for cis and trans V(D)J cleavage: effects of substrate length

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724672

V(D)J recombination: site-specific cleavage and repair

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724672

Transgenic models of lymphoid neoplasia and development of a pan-hematopoietic vector

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724672

Functional analysis of coordinated cleavage in V(D)J recombination

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724672

The 12/23 rule is enforced at the cleavage step of V(D)J recombination in vivo

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724672

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724672

Up-regulation of fibroblast growth factor 3 is associated with tumor metastasis and recurrence in human hepatocellular carcinoma

9 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724672

A central role for chromosome breakage in gene amplification, deletion formation, and amplicon integration

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724672

Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724672

V(D)J recombinase binding and cleavage of cryptic recombination signal sequences identified from lymphoid malignancies

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724672

Unrepaired DNA breaks in p53-deficient cells lead to oncogenic gene amplification subsequent to translocations.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2724672

Mitotic chromosome preparations from mouse cells for karyotyping

21 August 2018

1 reference

12 December 2020

Independent control of immunoglobulin switch recombination at individual switch regions evidenced through Cre-loxP-mediated gene targeting

1 reference

12 December 2020

Cell-free V(D)J recombination

1 reference

12 December 2020

Chromosomal inversion discovered in C3H/HeJ mice

1 reference

12 December 2020

The nonhomologous end joining factor Artemis suppresses multi-tissue tumor formation and prevents loss of heterozygosity

1 reference

12 December 2020

10.1158/0008-5472.CAN-08-4515

Identifiers

DOI

1 reference

9 September 2017

1 reference

9 September 2017

PubMed publication ID

19435904

1 reference