(Q39129195)

English

Increased activation of PI3K/AKT signaling pathway is associated with cholangiocarcinoma metastasis and PI3K/mTOR inhibition presents a possible therapeutic strategy

scientific article published on 6 July 2013

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

9 September 2017

Increased activation of PI3K/AKT signaling pathway is associated with cholangiocarcinoma metastasis and PI3K/mTOR inhibition presents a possible therapeutic strategy (English)

1 reference

Europe PubMed Central

PubMed publication ID

9 September 2017

cholangiocarcinoma

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Puangrat Yongvanit

5

object named as

Puangrat Yongvanit

1 reference

Europe PubMed Central

PubMed publication ID

9 September 2017

Watcharin Loilome

9

object named as

Watcharin Loilome

1 reference

Europe PubMed Central

PubMed publication ID

9 September 2017

author name string

Supak Yothaisong

1

1 reference

Europe PubMed Central

PubMed publication ID

9 September 2017

Hasaya Dokduang

2

1 reference

Europe PubMed Central

PubMed publication ID

9 September 2017

Anchalee Techasen

3

1 reference

Europe PubMed Central

PubMed publication ID

9 September 2017

Nisana Namwat

4

1 reference

Europe PubMed Central

PubMed publication ID

9 September 2017

Vajarabhongsa Bhudhisawasdi

6

1 reference

Europe PubMed Central

PubMed publication ID

9 September 2017

Anucha Puapairoj

7

1 reference

Europe PubMed Central

PubMed publication ID

9 September 2017

Gregory J Riggins

8

1 reference

Europe PubMed Central

PubMed publication ID

9 September 2017

publication date

6 July 2013

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Europe PubMed Central

PubMed publication ID

9 September 2017

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Europe PubMed Central

PubMed publication ID

9 September 2017

34

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Europe PubMed Central

PubMed publication ID

9 September 2017

6

1 reference

Europe PubMed Central

PubMed publication ID

9 September 2017

3637-3648

1 reference

Europe PubMed Central

PubMed publication ID

9 September 2017

Cancer control in Thailand

1 reference

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21 January 2018

Chronic infections and inflammatory processes as cancer risk factors: possible role of nitric oxide in carcinogenesis

1 reference

https://api.crossref.org/works/10.1007%2FS13277-013-0945-2

21 January 2018

Expression of oxysterol binding protein isoforms in opisthorchiasis-associated cholangiocarcinoma: a potential molecular marker for tumor metastasis.

1 reference

https://api.crossref.org/works/10.1007%2FS13277-013-0945-2

21 January 2018

Downregulation of reversion-inducing-cysteine-rich protein with Kazal motifs (RECK) is associated with enhanced expression of matrix metalloproteinases and cholangiocarcinoma metastases.

1 reference

https://api.crossref.org/works/10.1007%2FS13277-013-0945-2

21 January 2018

Myristoylated alanine-rich C kinase substrate phosphorylation promotes cholangiocarcinoma cell migration and metastasis via the protein kinase C-dependent pathway.

1 reference

https://api.crossref.org/works/10.1007%2FS13277-013-0945-2

21 January 2018

Cholangiocarcinoma: advances in pathogenesis, diagnosis, and treatment

1 reference

https://api.crossref.org/works/10.1007%2FS13277-013-0945-2

21 January 2018

Cholangiocarcinoma.

1 reference

https://api.crossref.org/works/10.1007%2FS13277-013-0945-2

21 January 2018

New paradigms in anticancer therapy: targeting multiple signaling pathways with kinase inhibitors.

1 reference

https://api.crossref.org/works/10.1007%2FS13277-013-0945-2

21 January 2018

Altered gene expression in Opisthorchis viverrini-associated cholangiocarcinoma in hamster model.

1 reference

https://api.crossref.org/works/10.1007%2FS13277-013-0945-2

21 January 2018

PRKAR1A is overexpressed and represents a possible therapeutic target in human cholangiocarcinoma.

1 reference

https://api.crossref.org/works/10.1007%2FS13277-013-0945-2

21 January 2018

Survey of activated kinase proteins reveals potential targets for cholangiocarcinoma treatment

1 reference

https://api.crossref.org/works/10.1007%2FS13277-013-0945-2

21 January 2018

Array comparative genomic hybridization identifies novel potential therapeutic targets in cholangiocarcinoma.

1 reference

https://api.crossref.org/works/10.1007%2FS13277-013-0945-2

21 January 2018

Novel expression patterns of PI3K/Akt/mTOR signaling pathway components in colorectal cancer.

1 reference

https://api.crossref.org/works/10.1007%2FS13277-013-0945-2

21 January 2018

Targeting the AKT pathway in glioblastoma

1 reference

https://api.crossref.org/works/10.1007%2FS13277-013-0945-2

21 January 2018

Inhibition of Akt inhibits growth of glioblastoma and glioblastoma stem-like cells

1 reference

https://api.crossref.org/works/10.1007%2FS13277-013-0945-2

21 January 2018

Fas-mediated apoptosis in cholangiocarcinoma cells is enhanced by 3,3'-diindolylmethane through inhibition of AKT signaling and FLICE-like inhibitory protein

1 reference

https://api.crossref.org/works/10.1007%2FS13277-013-0945-2

21 January 2018

Akt expression may predict favorable prognosis in cholangiocarcinoma.

1 reference

https://api.crossref.org/works/10.1007%2FS13277-013-0945-2

21 January 2018

The expression of phospho-AKT, phospho-mTOR, and PTEN in extrahepatic cholangiocarcinoma.

1 reference

https://api.crossref.org/works/10.1007%2FS13277-013-0945-2

21 January 2018

AKT and ERK1/2 signaling in intrahepatic cholangiocarcinoma

1 reference

https://api.crossref.org/works/10.1007%2FS13277-013-0945-2

21 January 2018

Induction of intrahepatic cholangiocellular carcinoma by liver-specific disruption of Smad4 and Pten in mice

1 reference

https://api.crossref.org/works/10.1007%2FS13277-013-0945-2

21 January 2018

Serine/threonine kinase AKT is frequently activated in human bile duct cancer and is associated with increased radioresistance.

1 reference

https://api.crossref.org/works/10.1007%2FS13277-013-0945-2

21 January 2018

The expression of phospho-AKT1 and phospho-MTOR is associated with a favorable prognosis independent of PTEN expression in intrahepatic cholangiocarcinomas.

1 reference

https://api.crossref.org/works/10.1007%2FS13277-013-0945-2

21 January 2018

Inhibition of PI3K increases oxaliplatin sensitivity in cholangiocarcinoma cells

1 reference

https://api.crossref.org/works/10.1007%2FS13277-013-0945-2

21 January 2018

Acquisition of chemoresistance in intrahepatic cholangiocarcinoma cells by activation of AKT and extracellular signal-regulated kinase (ERK)1/2.

1 reference

https://api.crossref.org/works/10.1007%2FS13277-013-0945-2

21 January 2018

Involvement of PI3K and ERK1/2 pathways in hepatocyte growth factor-induced cholangiocarcinoma cell invasion

1 reference

https://api.crossref.org/works/10.1007%2FS13277-013-0945-2

21 January 2018

NVP-BEZ235, a dual PI3K/mTOR inhibitor, prevents PI3K signaling and inhibits the growth of cancer cells with activating PI3K mutations.

1 reference

https://api.crossref.org/works/10.1007%2FS13277-013-0945-2

21 January 2018

Oxidized alpha-1 antitrypsin as a predictive risk marker of opisthorchiasis-associated cholangiocarcinoma

1 reference

https://api.crossref.org/works/10.1007%2FS13277-013-0945-2

21 January 2018

Oncogenic PI3K deregulates transcription and translation

1 reference

https://api.crossref.org/works/10.1007%2FS13277-013-0945-2

21 January 2018

Stimulation of phosphatidylinositol 3-kinase by fibroblast growth factor receptors is mediated by coordinated recruitment of multiple docking proteins

1 reference

https://api.crossref.org/works/10.1007%2FS13277-013-0945-2

21 January 2018

Ki-ras mutations and p53 protein expressions in intrahepatic cholangiocarcinomas: relation to gross tumor morphology.

1 reference

https://api.crossref.org/works/10.1007%2FS13277-013-0945-2

21 January 2018

Phosphorylation of AKT: a mutational analysis

1 reference

https://api.crossref.org/works/10.1007%2FS13277-013-0945-2

21 January 2018

The nuts and bolts of AGC protein kinases

1 reference

https://api.crossref.org/works/10.1007%2FS13277-013-0945-2

21 January 2018

Expression of cyclooxygenase-2 is regulated by glycogen synthase kinase-3beta in gastric cancer cells

1 reference

https://api.crossref.org/works/10.1007%2FS13277-013-0945-2

21 January 2018

Adiponectin modulates the glycogen synthase kinase-3beta/beta-catenin signaling pathway and attenuates mammary tumorigenesis of MDA-MB-231 cells in nude mice.

1 reference

https://api.crossref.org/works/10.1007%2FS13277-013-0945-2

21 January 2018

Glycogen synthase kinase 3beta (GSK3beta) in tumorigenesis and cancer chemotherapy

1 reference

https://api.crossref.org/works/10.1007%2FS13277-013-0945-2

21 January 2018

Glycogen synthase kinase (GSK)-3 promotes p70 ribosomal protein S6 kinase (p70S6K) activity and cell proliferation

1 reference

https://api.crossref.org/works/10.1007%2FS13277-013-0945-2

21 January 2018

Glycogen synthase kinase 3β inhibition sensitizes pancreatic cancer cells to gemcitabine

1 reference

https://api.crossref.org/works/10.1007%2FS13277-013-0945-2

21 January 2018

Identification and characterization of NVP-BEZ235, a new orally available dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor with potent in vivo antitumor activity

1 reference

https://api.crossref.org/works/10.1007%2FS13277-013-0945-2

21 January 2018

Dual phosphoinositide 3-kinase/mammalian target of rapamycin blockade is an effective radiosensitizing strategy for the treatment of non-small cell lung cancer harboring K-RAS mutations

1 reference

https://api.crossref.org/works/10.1007%2FS13277-013-0945-2

21 January 2018

NVP-BEZ235, a novel dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor, elicits multifaceted antitumor activities in human gliomas

1 reference

https://api.crossref.org/works/10.1007%2FS13277-013-0945-2

21 January 2018

NVP-BEZ235 as a new therapeutic option for sarcomas.

1 reference

https://api.crossref.org/works/10.1007%2FS13277-013-0945-2

21 January 2018

NVP-BEZ235 and NVP-BGT226, dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitors, enhance tumor and endothelial cell radiosensitivity

1 reference

https://api.crossref.org/works/10.1007%2FS13277-013-0945-2

21 January 2018

Dual targeting of the PI3K/Akt/mTOR pathway as an antitumor strategy in Waldenstrom macroglobulinemia.

1 reference

https://api.crossref.org/works/10.1007%2FS13277-013-0945-2

21 January 2018

Roles of the Akt/mTOR/p70S6K and ERK1/2 signaling pathways in curcumin-induced autophagy.

1 reference

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21 January 2018

Role of autophagy in temozolomide-induced cytotoxicity for malignant glioma cells

1 reference

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21 January 2018

Caffeine induces apoptosis by enhancement of autophagy via PI3K/Akt/mTOR/p70S6K inhibition

1 reference

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21 January 2018

Differential induction of apoptosis in HER2 and EGFR addicted cancers following PI3K inhibition.

1 reference

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21 January 2018

Augmentation of NVP-BEZ235's anticancer activity against human lung cancer cells by blockage of autophagy

1 reference

https://api.crossref.org/works/10.1007%2FS13277-013-0945-2

21 January 2018

p53 overexpression and K-ras gene mutations in primary sclerosing cholangitis-associated biliary tract cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/23832540

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Akt and autophagy cooperate to promote survival of drug-resistant glioma

1 reference

https://pubmed.ncbi.nlm.nih.gov/23832540

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of dimethylnitrosamine on induction of cholangiocarcinoma in Opisthorchis viverrini-infected Syrian golden hamsters

1 reference

https://pubmed.ncbi.nlm.nih.gov/23832540

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein expression and genetic alterations of p53 and ras in intrahepatic cholangiocarcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/23832540

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of microsatellite instability, K-ras gene mutation and p53 protein overexpression in intrahepatic cholangiocarcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/23832540

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The anticancer drug imatinib induces cellular autophagy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23832540

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The incidence of K-ras codon 12 mutations in cholangiocarcinoma detected by polymerase chain reaction technique.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23832540

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential effects of synthetic nuclear retinoid receptor-selective retinoids on the growth of human non-small cell lung carcinoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/23832540

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Growth inhibition by NVP-BEZ235, a dual PI3K/mTOR inhibitor, in hepatocellular carcinoma cell lines

1 reference

https://pubmed.ncbi.nlm.nih.gov/23832540

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple K-ras codon 12 mutations in cholangiocarcinomas demonstrated with a sensitive polymerase chain reaction technique.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23832540

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High incidence of ras gene mutation in intrahepatic cholangiocarcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/23832540

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidative and nitrative DNA damage: key events in opisthorchiasis-induced carcinogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23832540

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cancer genes and cholangiocarcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/23832540

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S13277-013-0945-2

1 reference

Europe PubMed Central

PubMed publication ID

9 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

9 September 2017

ResearchGate publication ID

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