(Q39149450)

English

Development of LC/MS/MS, high-throughput enzymatic and cellular assays for the characterization of compounds that inhibit kynurenine monooxygenase (KMO).

scientific article published on 20 May 2013

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

9 September 2017

Development of LC/MS/MS, high-throughput enzymatic and cellular assays for the characterization of compounds that inhibit kynurenine monooxygenase (KMO). (English)

1 reference

Europe PubMed Central

PubMed publication ID

9 September 2017

5

object named as

Andreas Ebneth

1 reference

Europe PubMed Central

PubMed publication ID

9 September 2017

Leticia Toledo-Sherman

3

object named as

Leticia M Toledo-Sherman

1 reference

Europe PubMed Central

PubMed publication ID

9 September 2017

author name string

Dirk Winkler

1

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Europe PubMed Central

PubMed publication ID

9 September 2017

Maria Beconi

2

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Europe PubMed Central

PubMed publication ID

9 September 2017

Michael Prime

4

1 reference

Europe PubMed Central

PubMed publication ID

9 September 2017

Celia Dominguez

6

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Europe PubMed Central

PubMed publication ID

9 September 2017

Ignacio Muñoz-Sanjuan

7

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Europe PubMed Central

PubMed publication ID

9 September 2017

publication date

20 May 2013

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Europe PubMed Central

PubMed publication ID

9 September 2017

Journal of Biomolecular Screening

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Europe PubMed Central

PubMed publication ID

9 September 2017

18

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Europe PubMed Central

PubMed publication ID

9 September 2017

8

1 reference

Europe PubMed Central

PubMed publication ID

9 September 2017

879-889

1 reference

Europe PubMed Central

PubMed publication ID

9 September 2017

Genetics and neuropathology of Huntington's disease

1 reference

https://api.crossref.org/works/10.1177%2F1087057113489731

21 January 2018

Huntington's disease: clinical presentation and treatment

1 reference

https://api.crossref.org/works/10.1177%2F1087057113489731

21 January 2018

Kynurenines in the mammalian brain: when physiology meets pathology

1 reference

https://api.crossref.org/works/10.1177%2F1087057113489731

21 January 2018

Targeting kynurenine 3-monooxygenase (KMO): implications for therapy in Huntington's disease

1 reference

https://api.crossref.org/works/10.1177%2F1087057113489731

21 January 2018

Histone deacetylase inhibition modulates kynurenine pathway activation in yeast, microglia, and mice expressing a mutant huntingtin fragment.

1 reference

https://api.crossref.org/works/10.1177%2F1087057113489731

21 January 2018

Elevated brain 3-hydroxykynurenine and quinolinate levels in Huntington disease mice

1 reference

https://api.crossref.org/works/10.1177%2F1087057113489731

21 January 2018

Kynurenic acid: a metabolite with multiple actions and multiple targets in brain and periphery

1 reference

https://api.crossref.org/works/10.1177%2F1087057113489731

21 January 2018

A genomic screen in yeast implicates kynurenine 3-monooxygenase as a therapeutic target for Huntington disease

1 reference

https://api.crossref.org/works/10.1177%2F1087057113489731

21 January 2018

Kynurenine 3-monooxygenase inhibition in blood ameliorates neurodegeneration

1 reference

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21 January 2018

Mass spectrometry for enzyme assays and inhibitor screening: an emerging application in pharmaceutical research.

1 reference

https://api.crossref.org/works/10.1177%2F1087057113489731

21 January 2018

Monitoring enzymatic conversions by mass spectrometry: a critical review

1 reference

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21 January 2018

Crystal Structure-Based Selective Targeting of the Pyridoxal 5′-Phosphate Dependent Enzyme Kynurenine Aminotransferase II for Cognitive Enhancement

1 reference

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21 January 2018

System Xc- and apolipoprotein E expressed by microglia have opposite effects on the neurotoxicity of amyloid-beta peptide 1-40.

1 reference

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21 January 2018

Synthesis and biochemical evaluation of N-(4-phenylthiazol-2-yl)benzenesulfonamides as high-affinity inhibitors of kynurenine 3-hydroxylase.

1 reference

https://api.crossref.org/works/10.1177%2F1087057113489731

21 January 2018

On the relationship between the two branches of the kynurenine pathway in the rat brain in vivo

1 reference

https://api.crossref.org/works/10.1177%2F1087057113489731

21 January 2018

4-Chloro-3-hydroxyanthranilate, 6-chlorotryptophan and norharmane attenuate quinolinic acid formation by interferon-gamma-stimulated monocytes (THP-1 cells).

1 reference

https://api.crossref.org/works/10.1177%2F1087057113489731

21 January 2018

Synthesis and release of neurotoxic kynurenine metabolites by human monocyte-derived macrophages

1 reference

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21 January 2018

Induction of indolamine 2,3-dioxygenase and kynurenine 3-monooxygenase in rat brain following a systemic inflammatory challenge: a role for IFN-gamma?

1 reference

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21 January 2018

Mitochondrial reactive oxygen species and calcium uptake regulate activation of phagocytic NADPH oxidase

1 reference

https://api.crossref.org/works/10.1177%2F1087057113489731

21 January 2018

Different kynurenine pathway enzymes limit quinolinic acid formation by various human cell types

1 reference

https://api.crossref.org/works/10.1177%2F1087057113489731

21 January 2018

Functional characterization and mechanism of action of recombinant human kynurenine 3-hydroxylase

1 reference

https://api.crossref.org/works/10.1177%2F1087057113489731

21 January 2018

Expression of the kynurenine enzymes in macrophages and microglial cells: regulation by immune modulators

1 reference

https://api.crossref.org/works/10.1177%2F1087057113489731

21 January 2018

Identifiers

10.1177/1087057113489731

1 reference

Europe PubMed Central

PubMed publication ID

9 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

9 September 2017

ResearchGate publication ID

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