(Q39163100)

9 September 2017

Chemical genetics reveals a kinase-independent role for protein kinase R in pyroptosis (English)

1 reference

9 September 2017

8

Deborah T Hung

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6615456&resulttype=core&format=json

15 May 2020

author name string

Erik C Hett

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6615456&resulttype=core&format=json

15 May 2020

Louise H Slater

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6615456&resulttype=core&format=json

15 May 2020

Kevin G Mark

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6615456&resulttype=core&format=json

15 May 2020

Tomohiko Kawate

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6615456&resulttype=core&format=json

15 May 2020

Brian G Monks

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6615456&resulttype=core&format=json

15 May 2020

Andrea Stutz

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6615456&resulttype=core&format=json

15 May 2020

Eicke Latz

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6615456&resulttype=core&format=json

15 May 2020

publication date

21 April 2013

1 reference

9 September 2017

Nature Chemical Biology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6615456&resulttype=core&format=json

15 May 2020

volume

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6615456&resulttype=core&format=json

15 May 2020

issue

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6615456&resulttype=core&format=json

15 May 2020

page(s)

398-405

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6615456&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/nchembio.1236

15 May 2020

exact match

0 references

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1236

Anthrax toxin: a tripartite lethal combination

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1236

The NLRP3 inflammasome in health and disease: the good, the bad and the ugly

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1236

Proteolytic inactivation of MAP-kinase-kinase by anthrax lethal factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1236

Anthrax lethal toxin: a weapon of multisystem destruction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1236

Cutting edge: resistance to Bacillus anthracis infection mediated by a lethal toxin sensitive allele of Nalp1b/Nlrp1b.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1236

Nalp1b controls mouse macrophage susceptibility to anthrax lethal toxin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1236

Anthrax lethal toxin rapidly activates caspase-1/ICE and induces extracellular release of interleukin (IL)-1beta and IL-18.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1236

Anthrax lethal factor cleavage of Nlrp1 is required for activation of the inflammasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1236

Novel role of PKR in inflammasome activation and HMGB1 release

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1236

Killing of macrophages by anthrax lethal toxin: involvement of the N-end rule pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1236

Macrophage apoptosis by anthrax lethal factor through p38 MAP kinase inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1236

The protein kinase PKR is required for macrophage apoptosis after activation of Toll-like receptor 4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1236

On the role of macrophages in anthrax

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1236

Anthrax and the inflammasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1236

Mouse susceptibility to anthrax lethal toxin is influenced by genetic factors in addition to those controlling macrophage sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1236

Anthrax toxin targeting of myeloid cells through the CMG2 receptor is essential for establishment of Bacillus anthracis infections in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1236

Susceptibility to anthrax lethal toxin-induced rat death is controlled by a single chromosome 10 locus that includes rNlrp1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1236

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1236

AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1236

Chemical genetic screening identifies critical pathways in anthrax lethal toxin-induced pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1236

Auranofin protects against anthrax lethal toxin-induced activation of the Nlrp1b inflammasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1236

Amiodarone and bepridil inhibit anthrax toxin entry into host cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1236

The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1236

Mechanism of interferon action: autoregulation of RNA-dependent P1/eIF-2 alpha protein kinase (PKR) expression in transfected mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1236

Small molecule inhibitors of the RNA-dependent protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1236

Impact of protein kinase PKR in cell biology: from antiviral to antiproliferative action

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1236

Double-stranded RNA-dependent protein kinase activates transcription factor NF-kappa B by phosphorylating I kappa B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1236

PKR stimulates NF-kappaB irrespective of its kinase function by interacting with the IkappaB kinase complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1236

Activation of the I kappa B alpha kinase (IKK) complex by double-stranded RNA-binding defective and catalytic inactive mutants of the interferon-inducible protein kinase PKR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1236

Activation of NF-κB pathway and TNF-α are involved in the cytotoxicity of anthrax lethal toxin in bovine BoMac macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1236

Mitochondrial impairment is a critical event in anthrax lethal toxin-induced cytolysis of murine macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1236

Cryopyrin activates the inflammasome in response to toxins and ATP

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1236

Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1236

Double-stranded RNA-activated protein kinase mediates virus-induced apoptosis: a new role for an old actor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1236

eIF-2 kinases: regulators of general and gene-specific translation initiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1236

TLR-induced NF-κB activation regulates NLRP3 expression in murine macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1236

Proteasome activity is required for anthrax lethal toxin to kill macrophages

21 January 2018

1 reference

12 December 2020

The N-terminus of PKR is responsible for the activation of the NF-kappaB signaling pathway by interacting with the IKK complex

1 reference

12 December 2020

The caspase-generated fragments of PKR cooperate to activate full-length PKR and inhibit translation

1 reference

12 December 2020

Inhibitors of anthrax lethal factor

1 reference

12 December 2020

Anthrax lethal toxin-induced inflammasome formation and caspase-1 activation are late events dependent on ion fluxes and the proteasome

1 reference

12 December 2020

The protein kinase PKR is critical for LPS-induced iNOS production but dispensable for inflammasome activation in macrophages

1 reference

12 December 2020

Macrophages are sensitive to anthrax lethal toxin through an acid-dependent process

1 reference

12 December 2020

The pathogenesis of the lethal effect of anthrax toxin in the rat

1 reference

12 December 2020

Identification of novel host-targeted compounds that protect from anthrax lethal toxin-induced cell death

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.1236

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/NCHEMBIO.1236

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6615456&resulttype=core&format=json

Dimensions Publication ID

15 May 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6615456&resulttype=core&format=json

15 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6615456&resulttype=core&format=json