(Q40167543)

18 September 2017

title

The caspase-generated fragments of PKR cooperate to activate full-length PKR and inhibit translation (English)

1 reference

18 September 2017

7

Saelens X

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18 September 2017

Kalai M

1

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18 September 2017

Suin V

2

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18 September 2017

Festjens N

3

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18 September 2017

Meeus A

4

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18 September 2017

Bernis A

5

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18 September 2017

Wang XM

6

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18 September 2017

Vandenabeele P

8

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18 September 2017

publication date

23 February 2007

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Cell Death & Differentiation

18 September 2017

published in

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18 September 2017

volume

14

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18 September 2017

issue

5

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18 September 2017

page(s)

1050-1059

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Toll-like receptor 3: a link between toll-like receptor, interferon and viruses

18 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402110

Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402110

Antiviral actions of interferons

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402110

PKR; a sentinel kinase for cellular stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402110

A dynamically tuned double-stranded RNA binding mechanism for the activation of antiviral kinase PKR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402110

Eukaryotic initiation factor eIF2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402110

Virus clearance through apoptosis-dependent phagocytosis of influenza A virus-infected cells by macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402110

The double-stranded RNA activated protein kinase PKR physically associates with the tumor suppressor p53 protein and phosphorylates human p53 on serine 392 in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402110

Double-stranded RNA-activated protein kinase is required for the LPS-induced activation of STAT1 inflammatory signaling in rat brain glial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402110

Activation of the dsRNA-dependent protein kinase, PKR, induces apoptosis through FADD-mediated death signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402110

Translation inhibition in apoptosis: caspase-dependent PKR activation and eIF2-alpha phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402110

Protein synthesis persists during necrotic cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402110

RIP1 is an essential mediator of Toll-like receptor 3-induced NF-kappa B activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402110

Apoptosis induced by the toll-like receptor adaptor TRIF is dependent on its receptor interacting protein homotypic interaction motif

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402110

Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402110

Disruption of HSP90 function reverts tumor necrosis factor-induced necrosis to apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402110

Poly(I-C)-induced Toll-like receptor 3 (TLR3)-mediated activation of NFkappa B and MAP kinase is through an interleukin-1 receptor-associated kinase (IRAK)-independent pathway employing the signaling components TLR3-TRAF6-TAK1-TAB2-PKR

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402110

Genomic loss and epigenetic silencing of very-low-density lipoprotein receptor involved in gastric carcinogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402110

A novel caspase-2 complex containing TRAF2 and RIP1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402110

Inhibitory sequences in the N-terminus of the double-stranded-RNA-dependent protein kinase, PKR, are important for regulating phosphorylation of eukaryotic initiation factor 2alpha (eIF2alpha).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402110

Mapping of the auto-inhibitory interactions of protein kinase R by nuclear magnetic resonance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402110

Structure of the double-stranded RNA-binding domain of the protein kinase PKR reveals the molecular basis of its dsRNA-mediated activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402110

Inhibition of the protein kinase PKR by the internal ribosome entry site of hepatitis C virus genomic RNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402110

The kinase activity of Rip1 is not required for tumor necrosis factor-alpha-induced IkappaB kinase or p38 MAP kinase activation or for the ubiquitination of Rip1 by Traf2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402110

PKR stimulates NF-kappaB irrespective of its kinase function by interacting with the IkappaB kinase complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402110

TRAF family proteins link PKR with NF-kappa B activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402110

Phagocytosis of necrotic cells by macrophages is phosphatidylserine dependent and does not induce inflammatory cytokine production

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402110

Regulated commitment of TNF receptor signaling: a molecular switch for death or activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402110

Caspase-independent cell killing by Fas-associated protein with death domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402110

Higher-Order Substrate Recognition of eIF2α by the RNA-Dependent Protein Kinase PKR

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402110

Mechanistic Link between PKR Dimerization, Autophosphorylation, and eIF2α Substrate Recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402110

Dynamic Flexibility of Double-stranded RNA Activated PKR in Solution

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402110

TIR domain-containing adaptors regulate TLR signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402110

7 January 2021

A model for the double-stranded RNA (dsRNA)-dependent dimerization and activation of the dsRNA-activated protein kinase PKR.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402110

7 January 2021

Tipping the balance between necrosis and apoptosis in human and murine cells treated with interferon and dsRNA.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402110

7 January 2021

Necrosis is associated with IL-6 production but apoptosis is not.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402110

7 January 2021

Differential signaling to apoptotic and necrotic cell death by Fas-associated death domain protein FADD.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402110

7 January 2021

Genetic deletion of PKR abrogates TNF-induced activation of IkappaBalpha kinase, JNK, Akt and cell proliferation but potentiates p44/p42 MAPK and p38 MAPK activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402110

7 January 2021

Activation of a pro-apoptotic amplification loop through inhibition of NF-kappaB-dependent survival signals by caspase-mediated inactivation of RIP

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402110

7 January 2021

Optimization of experimental variables influencing reporter gene expression in hepatoma cells following calcium phosphate transfection

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4402110

7 January 2021

Identifiers

DOI

10.1038/SJ.CDD.4402110

1 reference

Dimensions Publication ID

18 September 2017

1005978359

0 references

1 reference