(Q39185466)

9 September 2017

Hypoxia promotes tumor cell survival in acidic conditions by preserving ATP levels (English)

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9 September 2017

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4

Jacques Pouysségur

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9 September 2017

Scott K Parks

1

1 reference

PubMed ID

23459996

9 September 2017

Nathalie M Mazure

series ordinal

2

1 reference

PubMed ID

23459996

9 September 2017

Laurent Counillon

series ordinal

3

1 reference

9 September 2017

1 September 2013

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Journal of Cellular Physiology

9 September 2017

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9 September 2017

228

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9 September 2017

9

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9 September 2017

1854-1862

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Hypoxia-induced autophagy is mediated through hypoxia-inducible factor induction of BNIP3 and BNIP3L via their BH3 domains

9 September 2017

1 reference

Inhibition of lactate transport and glycolysis in Ehrlich ascites tumor cells by bioflavonoids

21 January 2018

1 reference

Targeting cancer cell metabolism: the combination of metformin and 2-deoxyglucose induces p53-dependent apoptosis in prostate cancer cells

21 January 2018

1 reference

The hypoxia-inducible-factor hydroxylases bring fresh air into hypoxia signalling

21 January 2018

1 reference

Arrest-defective-1 protein, an acetyltransferase, does not alter stability of hypoxia-inducible factor (HIF)-1alpha and is not induced by hypoxia or HIF

21 January 2018

1 reference

Hypoxia and energetic tumour metabolism

21 January 2018

1 reference

The genomic analysis of lactic acidosis and acidosis response in human cancers

21 January 2018

1 reference

Failure and function of intracellular pH regulation in acute hypoxic-ischemic injury of astrocytes

21 January 2018

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Hypoxia-inducible carbonic anhydrase IX and XII promote tumor cell growth by counteracting acidosis through the regulation of the intracellular pH.

21 January 2018

1 reference

In vivo pH in metabolic-defective Ras-transformed fibroblast tumors: key role of the monocarboxylate transporter, MCT4, for inducing an alkaline intracellular pH.

21 January 2018

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Lactic acid and acidification inhibit TNF secretion and glycolysis of human monocytes

21 January 2018

1 reference

Oligomycin inhibits HIF-1alpha expression in hypoxic tumor cells

21 January 2018

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The proton-linked monocarboxylate transporter (MCT) family: structure, function and regulation

21 January 2018

1 reference

Acidic stress promotes a glioma stem cell phenotype.

21 January 2018

1 reference

Regulation of intracellular pH in cancer cell lines under normoxia and hypoxia

21 January 2018

1 reference

Differential toxic mechanisms of 2-deoxy-D-glucose versus 2-fluorodeoxy-D-glucose in hypoxic and normoxic tumor cells

21 January 2018

1 reference

Energy budget of hepatocytes from Antarctic fish (Pachycara brachycephalum and Lepidonotothen kempi) as a function of ambient CO2: pH-dependent limitations of cellular protein biosynthesis?

21 January 2018

1 reference

CD147 subunit of lactate/H+ symporters MCT1 and hypoxia-inducible MCT4 is critical for energetics and growth of glycolytic tumors

21 January 2018

1 reference

Targeting tumor hypoxia: suppression of breast tumor growth and metastasis by novel carbonic anhydrase IX inhibitors.

21 January 2018

1 reference

Autophagy is a protective mechanism for human melanoma cells under acidic stress

21 January 2018

1 reference

2-deoxy-D-glucose increases the efficacy of adriamycin and paclitaxel in human osteosarcoma and non-small cell lung cancers in vivo

21 January 2018

1 reference

The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

21 January 2018

1 reference

Carbonic anhydrase IX promotes tumor growth and necrosis in vivo and inhibition enhances anti-VEGF therapy

21 January 2018

1 reference

HIF activation by pH-dependent nucleolar sequestration of VHL.

21 January 2018

1 reference

Targeting hypoxic tumor cell viability with carbohydrate-based carbonic anhydrase IX and XII inhibitors

21 January 2018

1 reference

pH control mechanisms of tumor survival and growth

21 January 2018

1 reference

Glycogen Synthesis is Induced in Hypoxia by the Hypoxia-Inducible Factor and Promotes Cancer Cell Survival

21 January 2018

1 reference

A specific mutation abolishing Na+/H+ antiport activity in hamster fibroblasts precludes growth at neutral and acidic pH

21 January 2018

1 reference

Hypoxia signalling in cancer and approaches to enforce tumour regression

21 January 2018

1 reference

p42/p44 mitogen-activated protein kinases phosphorylate hypoxia-inducible factor 1alpha (HIF-1alpha) and enhance the transcriptional activity of HIF-1.

21 January 2018

1 reference

CD147 silencing inhibits lactate transport and reduces malignant potential of pancreatic cancer cells in in vivo and in vitro models.

21 January 2018

1 reference

Hypoxic but not anoxic stabilization of HIF-1alpha requires mitochondrial reactive oxygen species

21 January 2018

1 reference

Hypoxia-inducible factors in physiology and medicine

21 January 2018

1 reference

Hypoxia-inducible factor 1-mediated regulation of PPP1R3C promotes glycogen accumulation in human MCF-7 cells under hypoxia

21 January 2018

1 reference

2-Deoxy-D-glucose combined with cisplatin enhances cytotoxicity via metabolic oxidative stress in human head and neck cancer cells

21 January 2018

1 reference

Astrocyte energetics, function, and death under conditions of incomplete ischemia: a mechanism of glial death in the penumbra.

21 January 2018

1 reference

Tumor-associated carbonic anhydrase 9 spatially coordinates intracellular pH in three-dimensional multicellular growths

21 January 2018

1 reference

The role of carbonic anhydrase 9 in regulating extracellular and intracellular ph in three-dimensional tumor cell growths

21 January 2018

1 reference

Functional interaction between responses to lactic acidosis and hypoxia regulates genomic transcriptional outputs.

21 January 2018

1 reference

Regulation of Na+/H+ exchanger 1 allosteric balance by its localization in cholesterol- and caveolin-rich membrane microdomains.

21 January 2018

1 reference

Chronic autophagy is a cellular adaptation to tumor acidic pH microenvironments

21 January 2018

1 reference

Multiparameter metabolic analysis reveals a close link between attenuated mitochondrial bioenergetic function and enhanced glycolysis dependency in human tumor cells

21 January 2018

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Intracellular ATP levels are a pivotal determinant of chemoresistance in colon cancer cells

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/JCP.24346

1 reference

9 September 2017

1 reference

PubMed ID

23459996