(Q39214188)

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Tetra-O-methyl nordihydroguaiaretic acid, an inhibitor of Sp1-mediated survivin transcription, induces apoptosis and acts synergistically with chemo-radiotherapy in glioblastoma cells

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scholarly article

1 reference

Europe PubMed Central

10 September 2017

Tetra-O-methyl nordihydroguaiaretic acid, an inhibitor of Sp1-mediated survivin transcription, induces apoptosis and acts synergistically with chemo-radiotherapy in glioblastoma cells. (English)

1 reference

Europe PubMed Central

10 September 2017

apoptotic process

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radiation therapy

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1 reference

based on heuristic

inferred from title

Kleiton Silva Borges

2

1 reference

Europe PubMed Central

10 September 2017

Harley Francisco de Oliveira

object named as

Harley Francisco de Oliveira

7

0 references

Angel Mauricio Castro-Gamero

object named as

Angel Mauricio Castro-Gamero

1

0 references

Carlos Scrideli

object named as

Carlos Alberto Scrideli

9

0 references

Carlos Gilberto Carlotti

8

object named as

Carlos Gilberto Carlotti

1 reference

Europe PubMed Central

10 September 2017

author name string

Daniel Antunes Moreno

3

1 reference

Europe PubMed Central

10 September 2017

Veridiana Kill Suazo

4

1 reference

Europe PubMed Central

10 September 2017

Mayara Missono Fujinami

5

1 reference

Europe PubMed Central

10 September 2017

Rosane de Paula Gomes Queiroz

6

1 reference

Europe PubMed Central

10 September 2017

Luiz Gonzaga Tone

10

1 reference

Europe PubMed Central

10 September 2017

language of work or name

1 reference

based on heuristic

inferred from title

publication date

9 January 2013

1 reference

Europe PubMed Central

10 September 2017

Investigational New Drugs

1 reference

Europe PubMed Central

10 September 2017

31

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Europe PubMed Central

10 September 2017

4

1 reference

Europe PubMed Central

10 September 2017

858-870

1 reference

Europe PubMed Central

10 September 2017

https://scigraph.springernature.com/pub.10.1007/s10637-012-9917-4

0 references

Advances in the treatment of malignant gliomas

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9917-4

21 January 2018

Conventional and gene therapy strategies for the treatment of brain tumors

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9917-4

21 January 2018

Treatment of glioblastoma multiforme: a new standard

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9917-4

21 January 2018

Radiation-induced apoptosis

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9917-4

21 January 2018

Structural, functional and therapeutic biology of survivin

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9917-4

21 January 2018

Induction of apoptosis and inhibition of cell proliferation by survivin gene targeting

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9917-4

21 January 2018

Survivin, versatile modulation of cell division and apoptosis in cancer

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9917-4

21 January 2018

Survivin: a new target for anti-cancer therapy

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9917-4

21 January 2018

Quantitatively determined survivin expression levels are of prognostic value in human gliomas

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9917-4

21 January 2018

Survivin enhances radiation resistance in primary human glioblastoma cells via caspase-independent mechanisms

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9917-4

21 January 2018

Survivin inhibition and DNA double-strand break repair: a molecular mechanism to overcome radioresistance in glioblastoma.

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9917-4

21 January 2018

Regulation of apoptosis at cell division by p34cdc2 phosphorylation of survivin

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9917-4

21 January 2018

Cyclin dependent kinase 1 inhibitors: a review of recent progress

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9917-4

21 January 2018

To cycle or not to cycle: a critical decision in cancer.

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9917-4

21 January 2018

Cell cycle, CDKs and cancer: a changing paradigm

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9917-4

21 January 2018

A haplotype variation affecting the mitochondrial transportation of hMYH protein could be a risk factor for colorectal cancer in Chinese

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9917-4

21 January 2018

Tetra-O-methyl nordihydroguaiaretic acid induces growth arrest and cellular apoptosis by inhibiting Cdc2 and survivin expression

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9917-4

21 January 2018

Phase I study of terameprocol in patients with recurrent high-grade glioma

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9917-4

21 January 2018

The 2007 WHO classification of tumours of the central nervous system

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9917-4

21 January 2018

Inhibition of Aurora kinases enhances chemosensitivity to temozolomide and causes radiosensitization in glioblastoma cells.

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9917-4

21 January 2018

Polyploidy in atypical grade II choroid plexus papilloma of the posterior fossa.

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9917-4

21 January 2018

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9917-4

21 January 2018

Selection of suitable housekeeping genes for expression analysis in glioblastoma using quantitative RT-PCR

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9917-4

21 January 2018

Inhibition of nuclear factor-κB by dehydroxymethylepoxyquinomicin induces schedule-dependent chemosensitivity to anticancer drugs and enhances chemoinduced apoptosis in osteosarcoma cells

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9917-4

21 January 2018

Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9917-4

21 January 2018

Clonogenic assay of cells in vitro.

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9917-4

21 January 2018

Genetic pathways to primary and secondary glioblastoma

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9917-4

21 January 2018

Using gene expression profiling to identify a prognostic molecular spectrum in gliomas

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9917-4

21 January 2018

Novel therapies in glioblastoma

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9917-4

21 January 2018

Mechanisms of acquired resistance to targeted cancer therapies.

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9917-4

21 January 2018

New wirings in the survivin networks

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9917-4

21 January 2018

Cyclin-dependent kinase pathways as targets for cancer treatment

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9917-4

21 January 2018

Transcriptional expression of survivin and its splice variants in brain tumors in humans

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9917-4

21 January 2018

Activity of PXD101, a histone deacetylase inhibitor, in preclinical ovarian cancer studies

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9917-4

21 January 2018

tetra-O-methylnordihydroguaiaretic acid inhibits melanoma in vivo

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9917-4

21 January 2018

Synthesis, characterization, and anti-melanoma activity of tetra-O-substituted analogs of nordihydroguaiaretic acid

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9917-4

21 January 2018

Systemic treatment with tetra-O-methyl nordihydroguaiaretic acid suppresses the growth of human xenograft tumors

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9917-4

21 January 2018

Tetra-O-methyl nordihydroguaiaretic acid inhibits growth and induces death of leukemia cells independent of Cdc2 and survivin

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9917-4

21 January 2018

Novel agents and regimens for acute myeloid leukemia: 2009 ASH annual meeting highlights

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9917-4

21 January 2018

CDC2/CDK1 expression in esophageal adenocarcinoma and precursor lesions serves as a diagnostic and cancer progression marker and potential novel drug target.

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9917-4

21 January 2018

Analysis of gene expression and chemoresistance of CD133+ cancer stem cells in glioblastoma

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9917-4

21 January 2018

The relevance of drug sequence in combination chemotherapy

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9917-4

21 January 2018

Transcriptional repression of the anti-apoptotic survivin gene by wild type p53.

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9917-4

21 January 2018

Cancer cells survive with survivin

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9917-4

21 January 2018

Frequent co-alterations of TP53, p16/CDKN2A, p14ARF, PTEN tumor suppressor genes in human glioma cell lines.

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9917-4

21 January 2018

Terameprocol (tetra-O-methyl nordihydroguaiaretic acid), an inhibitor of Sp1-mediated survivin transcription, induces radiosensitization in non-small cell lung carcinoma

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9917-4

21 January 2018

XIAP and survivin as therapeutic targets for radiation sensitization in preclinical models of lung cancer

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9917-4

21 January 2018

Survivin antisense oligonucleotides effectively radiosensitize colorectal cancer cells in both tissue culture and murine xenograft models

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9917-4

21 January 2018

Downregulation of survivin by siRNA diminishes radioresistance of pancreatic cancer cells.

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9917-4

21 January 2018

Targeting apoptosis pathways in glioblastoma

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9917-4

21 January 2018

Type I IFNs signaling and apoptosis resistance in glioblastoma cells.

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9917-4

21 January 2018

Mechanistic evaluation of the novel HSP90 inhibitor NVP-AUY922 in adult and pediatric glioblastoma

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9917-4

21 January 2018

Pediatric glioblastoma cell line shows different patterns of expression of transmembrane ABC transporters after in vitro exposure to vinblastine.

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9917-4

21 January 2018

Molecular and phenotypic characterisation of paediatric glioma cell lines as models for preclinical drug development

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9917-4

21 January 2018

Alternative splice variants of survivin as potential targets in cancer

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9917-4

21 January 2018

Characterization of an anti-apoptotic glycoprotein encoded by Kaposi's sarcoma-associated herpesvirus which resembles a spliced variant of human survivin

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9917-4

21 January 2018

An alternatively spliced survivin variant is positively regulated by p53 and sensitizes leukemia cells to chemotherapy

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9917-4

21 January 2018

Forced expression of survivin-2B abrogates mitotic cells and induces mitochondria-dependent apoptosis by blockade of tubulin polymerization and modulation of Bcl-2, Bax, and survivin

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9917-4

21 January 2018

Levels of effectiveness of gene therapies targeting survivin and its splice variants in human breast cancer cells

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9917-4

21 January 2018

Survivin splice variants are not essential for mitotic progression or inhibition of apoptosis induced by doxorubicin and radiation

1 reference

https://api.crossref.org/works/10.1007%2FS10637-012-9917-4

21 January 2018

Tetra-O-methyl nordihydroguaiaretic acid induces G2 arrest in mammalian cells and exhibits tumoricidal activity in vivo.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23299390

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Survivin-deltaEx3 and survivin-2B: two novel splice variants of the apoptosis inhibitor survivin with different antiapoptotic properties

1 reference

https://pubmed.ncbi.nlm.nih.gov/23299390

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of proline-directed protein kinase, (p34cdc2/p58cyclin A), a novel cell proliferation marker in childhood brain tumors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23299390

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Radiosensitizing effect of YM155, a novel small-molecule survivin suppressant, in non-small cell lung cancer cell lines

1 reference

https://pubmed.ncbi.nlm.nih.gov/23299390

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell cycle-mediated drug resistance: an emerging concept in cancer therapy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23299390

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Therapeutic targeting of the survivin pathway in cancer: initiation of mitochondrial apoptosis and suppression of tumor-associated angiogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23299390

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression of CDC2/CyclinB1 in gliomas, and CDC2 depletion inhibits proliferation of human glioma cells in vitro and in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/23299390

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The anticancer activity of the transcription inhibitor terameprocol (meso-tetra-O-methyl nordihydroguaiaretic acid) formulated for systemic administration

1 reference

https://pubmed.ncbi.nlm.nih.gov/23299390

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S10637-012-9917-4

1 reference

Europe PubMed Central

10 September 2017

1 reference

Europe PubMed Central

10 September 2017

ResearchGate publication ID

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