(Q39261999)

10 September 2017

Chemotherapeutic agents induce the expression and activity of their clearing enzyme CYP3A4 by activating p53. (English)

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10 September 2017

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Ido Goldstein

1

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Varda Rotter

7

object named as

Varda Rotter

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10 September 2017

Noa Rivlin

2

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10 September 2017

Or-yam Shoshana

3

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10 September 2017

Osnat Ezra

4

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10 September 2017

Shalom Madar

5

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10 September 2017

Naomi Goldfinger

6

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10 September 2017

language of work or name

English

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publication date

10 October 2012

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10 September 2017

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10 September 2017

34

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10 September 2017

190-198

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10 September 2017

1

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Clinical importance of the cytochromes P450

10 September 2017

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS318

Comparison of cytochrome P450 (CYP) genes from the mouse and human genomes, including nomenclature recommendations for genes, pseudogenes and alternative-splice variants

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS318

The role of nuclear receptors in pharmacokinetic drug-drug interactions in oncology

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS318

Drugs behave as substrates, inhibitors and inducers of human cytochrome P450 3A4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS318

Induction of cytochrome P450 3A4 in primary human hepatocytes and activation of the human pregnane X receptor by tamoxifen and 4-hydroxytamoxifen

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS318

Pharmacokinetics of anastrozole and tamoxifen alone, and in combination, during adjuvant endocrine therapy for early breast cancer in postmenopausal women: a sub-protocol of the 'Arimidex and tamoxifen alone or in combination' (ATAC) trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS318

The human cytochrome P450 sub-family: transcriptional regulation, inter-individual variation and interaction networks

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS318

Cytochrome P450 omega hydroxylase (CYP4) function in fatty acid metabolism and metabolic diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS318

Cytochrome P450 4F subfamily: at the crossroads of eicosanoid and drug metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS318

Genistein, resveratrol, and 5-aminoimidazole-4-carboxamide-1-β-D-ribofuranoside induce cytochrome P450 4F2 expression through an AMP-activated protein kinase-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS318

Understanding wild-type and mutant p53 activities in human cancer: new landmarks on the way to targeted therapies

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS318

Blinded by the Light: The Growing Complexity of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS318

Regulation of lipid metabolism by p53 - fighting two villains with one sword.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS318

Metabolic regulation by p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS318

Cell cycle regulation via p53 phosphorylation by a 5'-AMP activated protein kinase activator, 5-aminoimidazole- 4-carboxamide-1-beta-D-ribofuranoside, in a human hepatocellular carcinoma cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS318

AMP-activated protein kinase induces a p53-dependent metabolic checkpoint

21 January 2018

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https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS318

AMP-activated protein kinase: an energy sensor that regulates all aspects of cell function

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS318

GAMT, a p53-inducible modulator of apoptosis, is critical for the adaptive response to nutrient stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS318

Tumor suppressor p53 regulates bile acid homeostasis via small heterodimer partner

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS318

Pancreatic and duodenal homeobox gene 1 induces hepatic dedifferentiation by suppressing the expression of CCAAT/enhancer-binding protein beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS318

Luminogenic cytochrome P450 assays

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS318

Activation of P53 in HepG2 cells as surrogate to detect mutagens and promutagens in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS318

In vivo activation of the p53 pathway by small-molecule antagonists of MDM2

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS318

p53, a novel regulator of lipid metabolism pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS318

The expanding universe of p53 targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS318

The p53MH algorithm and its application in detecting p53-responsive genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS318

ROS-mediated p53 induction of Lpin1 regulates fatty acid oxidation in response to nutritional stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS318

Pharmacokinetic evaluation of doxorubicin plasma levels in normal and overweight patients with breast cancer and simulation of dose adjustment by different indexes of body mass

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS318

Direct assessment of promoter activity of human cytochrome p450 genes using optimized transfection in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS318

Development of an in vitro reporter gene assay to assess xenobiotic induction of the human CYP3A4 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS318

Small-molecule inhibitors of the MDM2-p53 protein-protein interaction to reactivate p53 function: a novel approach for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCARCIN%2FBGS318

21 January 2018

Identifiers

DOI

10.1093/CARCIN/BGS318

1 reference

release_2ia7bvm5ezdrfayq3u5awp27fq

10 September 2017

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1 reference