(Q39278644)

10 September 2017

1 reference

title

Enzymatic Halogenation: A Timely Strategy for Regioselective C-H Activation (English)

1 reference

10 September 2017

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28464370%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

Norbert Sewald

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28464370%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

author name string

Christian Schnepel

series ordinal

1

1 reference

10 September 2017

Norbert Sewald

series ordinal

2

1 reference

10 September 2017

language of work or name

English

0 references

publication date

2 May 2017

1 reference

Chemistry—A European Journal

10 September 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28464370%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

volume

23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28464370%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

issue

50

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28464370%20AND%20SRC:MED&resulttype=core&format=json

8 June 2020

page(s)

12064-12086

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28464370%20AND%20SRC:MED&resulttype=core&format=json

Industrial biocatalysis today and tomorrow

8 June 2020

cites work

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201701209

Recent progress in industrial biocatalysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201701209

Biocatalytic asymmetric synthesis of chiral amines from ketones applied to sitagliptin manufacture

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201701209

Biocatalysis in organic chemistry and biotechnology: past, present, and future

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201701209

Engineering the third wave of biocatalysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201701209

Modern Transition-Metal-Catalyzed Carbon-Halogen Bond Formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201701209

Natural Organohalogens: A New Frontier for Medicinal Agents?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201701209

Biosynthesis of the dichloroacetyl component of chloramphenicol in Streptomyces venezuelae ISP5230: genes required for halogenation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201701209

The diversity of naturally occurring organobromine compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201701209

Crystal structure and mechanism of a bacterial fluorinating enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201701209

Enzymatic fluorination and biotechnological developments of the fluorinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201701209

SyrB2 in syringomycin E biosynthesis is a nonheme FeII alpha-ketoglutarate- and O2-dependent halogenase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201701209

A new family of iron-dependent halogenases acts on freestanding substrates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201701209

Purification and Partial Characterization of Tryptophan 7-Halogenase (PrnA) from Pseudomonas fluorescens This work was supported by the Deutsche Forschungsgemeinschaft (DFG) through the Graduiertenkolleg "Struktur-Eigenschafts-Beziehungen bei Hetero

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201701209

Robust in vitro activity of RebF and RebH, a two-component reductase/halogenase, generating 7-chlorotryptophan during rebeccamycin biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201701209

The biosynthetic gene cluster for the antitumor rebeccamycin: characterization and generation of indolocarbazole derivatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201701209

Enzymatic assembly of the bis-indole core of rebeccamycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201701209

A regioselective tryptophan 5-halogenase is involved in pyrroindomycin biosynthesis in Streptomyces rugosporus LL-42D005.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201701209

Tandem action of the O2- and FADH2-dependent halogenases KtzQ and KtzR produce 6,7-dichlorotryptophan for kutzneride assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201701209

Characterization of a tryptophan 6-halogenase from Streptomyces toxytricini

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201701209

Microbisporicin gene cluster reveals unusual features of lantibiotic biosynthesis in actinomycetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201701209

Two Flavoenzymes Catalyze the Post-Translational Generation of 5-Chlorotryptophan and 2-Aminovinyl-Cysteine during NAI-107 Biosynthesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201701209

Structure and biocatalytic scope of thermophilic flavin-dependent halogenase and flavin reductase enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201701209

Crystallization and X-ray diffraction of a halogenating enzyme, tryptophan 7-halogenase, from Pseudomonas fluorescens

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201701209

Tryptophan 7-halogenase (PrnA) structure suggests a mechanism for regioselective chlorination

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201701209

The structure of flavin-dependent tryptophan 7-halogenase RebH

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201701209

Flavin dependent monooxygenases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201701209

Flavin redox chemistry precedes substrate chlorination during the reaction of the flavin-dependent halogenase RebH.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201701209

Chlorination by a long-lived intermediate in the mechanism of flavin-dependent halogenases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201701209

New Insights into the Mechanism of Enzymatic Chlorination of Tryptophan

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201701209

Structural Insights into Regioselectivity in the Enzymatic Chlorination of Tryptophan

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201701209

A Structure-Guided Switch in the Regioselectivity of a Tryptophan Halogenase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201701209

Structure and action of the myxobacterial chondrochloren halogenase CndH: a new variant of FAD-dependent halogenases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201701209

Chloramphenicol biosynthesis: the structure of CmlS, a flavin-dependent halogenase showing a covalent flavin-aspartate bond

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201701209

Regiospecific chlorination of (S)-beta-tyrosyl-S-carrier protein catalyzed by SgcC3 in the biosynthesis of the enediyne antitumor antibiotic C-1027

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201701209

Molecular and biochemical studies of chondramide formation-highly cytotoxic natural products from Chondromyces crocatus Cm c5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201701209

Regioselective arene halogenation using the FAD-dependent halogenase RebH.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201701209

Enzyme immobilisation in biocatalysis: why, what and how.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201701209

Enzymatic halogenation of tryptophan on a gram scale

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201701209

Integrated catalysis opens new arylation pathways via regiodivergent enzymatic C-H activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201701209

Extending the biocatalytic scope of regiocomplementary flavin-dependent halogenase enzymes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201701209

Understanding Flavin-Dependent Halogenase Reactivity via Substrate Activity Profiling

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201701209

Directed evolution drives the next generation of biocatalysts

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201701209

A high-throughput assay for arylamine halogenation based on a peroxidase-mediated quinone-amine coupling with applications in the screening of enzymatic halogenations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201701209

Directed Evolution of RebH for Catalyst-Controlled Halogenation of Indole C-H Bonds

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201701209

A High-Throughput Fluorescence Assay to Determine the Activity of Tryptophan Halogenases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201701209

Development of fluorescent aryltryptophans by Pd mediated cross-coupling of unprotected halotryptophans in water

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201701209

Protein stability promotes evolvability

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201701209

Improving the Stability and Catalyst Lifetime of the Halogenase RebH By Directed Evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201701209

Directed evolution of RebH for site-selective halogenation of large biologically active molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201701209

Changing the regioselectivity of the tryptophan 7-halogenase PrnA by site-directed mutagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201701209

Combinatorial biosynthesis of antitumor indolocarbazole compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201701209

Use of a halogenase of hormaomycin biosynthesis for formation of new clorobiocin analogues with 5-chloropyrrole moieties

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201701209

Engineering fluorometabolite production: fluorinase expression in Salinispora tropica Yields Fluorosalinosporamide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201701209

Chemistry and biology of monoterpene indole alkaloid biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201701209

Directed biosynthesis of alkaloid analogs in the medicinal plant Catharanthus roseus

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201701209

Rapid identification of enzyme variants for reengineered alkaloid biosynthesis in periwinkle

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201701209

Integrating carbon-halogen bond formation into medicinal plant metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201701209

Reengineering a tryptophan halogenase to preferentially chlorinate a direct alkaloid precursor

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201701209

Combining the 'two worlds' of chemocatalysis and biocatalysis towards multi-step one-pot processes in aqueous media

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201701209

Modular chemoenzymatic one-pot syntheses in aqueous media: combination of a palladium-catalyzed cross-coupling with an asymmetric biotransformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201701209

Gene expression enabling synthetic diversification of natural products: chemogenetic generation of pacidamycin analogs

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201701209

Late-Stage Diversification of Biologically Active Molecules via Chemoenzymatic C-H Functionalization

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201701209

Sonogashira diversification of unprotected halotryptophans, halotryptophan containing tripeptides; and generation of a new to nature bromo-natural product and its diversification in water.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201701209

A flavin-dependent tryptophan 6-halogenase and its use in modification of pyrrolnitrin biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201701209

Änderung der Regioselektivität der Tryptophan-7-Halogenase PrnA durch ortsspezifische Mutagenese

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201701209

Crystal structure of the non-haem iron halogenase SyrB2 in syringomycin biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201701209