(Q39297691)

10 September 2017

title

Influenza A virus-encoded NS1 virulence factor protein inhibits innate immune response by targeting IKK. (English)

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10 September 2017

Influenza A virus

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Shijuan Gao

1

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10 September 2017

Liping Song

2

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10 September 2017

Jiandong Li

3

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10 September 2017

Zhenzhu Zhang

4

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10 September 2017

Haiyan Peng

5

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10 September 2017

Wei Jiang

6

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10 September 2017

Qingtao Wang

7

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10 September 2017

Tiebang Kang

8

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10 September 2017

Shuai Chen

9

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10 September 2017

Wenlin Huang

10

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10 September 2017

publication date

17 September 2012

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10 September 2017

published in

Cellular Microbiology

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10 September 2017

volume

14

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10 September 2017

issue

12

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10 September 2017

page(s)

1849-1866

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A nucleosomal function for IkappaB kinase-alpha in NF-kappaB-dependent gene expression

10 September 2017

cites work

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Strain-specific contribution of NS1-activated phosphoinositide 3-kinase signaling to influenza A virus replication and virulence

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Influenza virus NS1 protein counteracts PKR-mediated inhibition of replication.

21 January 2018

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X-ray structure of influenza virus NS1 effector domain

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The morphology and composition of influenza A virus particles are not affected by low levels of M1 and M2 proteins in infected cells

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Inhibition of IkappaB kinase by vaccinia virus virulence factor B14

21 January 2018

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Signaling to chromatin through histone modifications

21 January 2018

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A novel RNA-binding motif in influenza A virus non-structural protein 1

21 January 2018

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Structural basis for suppression of a host antiviral response by influenza A virus

21 January 2018

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A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB

21 January 2018

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A novel inhibitor of the NF-{kappa}B signaling pathway encoded by the parapoxvirus orf virus

21 January 2018

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A recombinant influenza A virus expressing an RNA-binding-defective NS1 protein induces high levels of beta interferon and is attenuated in mice

21 January 2018

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Influenza A virus NS1 protein activates the PI3K/Akt pathway to mediate antiapoptotic signaling responses

21 January 2018

1 reference

Influenza virus-induced NF-kappaB-dependent gene expression is mediated by overexpression of viral proteins and involves oxidative radicals and activation of IkappaB kinase

21 January 2018

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Multifunctional adaptive NS1 mutations are selected upon human influenza virus evolution in the mouse.

21 January 2018

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Pandemic potential of a strain of influenza A (H1N1): early findings

21 January 2018

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Influenza A virus NS1 targets the ubiquitin ligase TRIM25 to evade recognition by the host viral RNA sensor RIG-I

21 January 2018

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Influenza A Virus Lacking the NS1 Gene Replicates in Interferon-Deficient Systems

21 January 2018

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Cellular transcriptional profiling in influenza A virus-infected lung epithelial cells: the role of the nonstructural NS1 protein in the evasion of the host innate defense and its potential contribution to pandemic influenza

21 January 2018

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NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses

21 January 2018

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The avian influenza virus NS1 ESEV PDZ binding motif associates with Dlg1 and Scribble to disrupt cellular tight junctions

21 January 2018

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NS1 protein of influenza A virus inhibits the function of intracytoplasmic pathogen sensor, RIG-I

21 January 2018

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Influenza A virus NS1 protein binds p85beta and activates phosphatidylinositol-3-kinase signaling

21 January 2018

1 reference

Structure of an avian influenza A virus NS1 protein effector domain

21 January 2018

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The multifunctional NS1 protein of influenza A viruses

21 January 2018

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Inefficient control of host gene expression by the 2009 pandemic H1N1 influenza A virus NS1 protein

21 January 2018

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The HA and NS genes of human H5N1 influenza A virus contribute to high virulence in ferrets

21 January 2018

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A new influenza virus virulence determinant: the NS1 protein four C-terminal residues modulate pathogenicity

21 January 2018

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Fatal outcome of human influenza A (H5N1) is associated with high viral load and hypercytokinemia

21 January 2018

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Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity

21 January 2018

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Aberrant innate immune response in lethal infection of macaques with the 1918 influenza virus

21 January 2018

1 reference

NF-kappaB signaling differentially regulates influenza virus RNA synthesis

21 January 2018

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Deactivation of the kinase IKK by CUEDC2 through recruitment of the phosphatase PP1.

21 January 2018

1 reference

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

21 January 2018

1 reference

Influenza viruses and the NF-kappaB signaling pathway - towards a novel concept of antiviral therapy

21 January 2018

1 reference

Influenza-virus-induced signaling cascades: targets for antiviral therapy?

21 January 2018

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Influenza virus NS1 protein interacts with the cellular 30 kDa subunit of CPSF and inhibits 3'end formation of cellular pre-mRNAs

21 January 2018

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Generation of influenza A viruses entirely from cloned cDNAs

21 January 2018

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Active NF-kappaB signalling is a prerequisite for influenza virus infection.

21 January 2018

1 reference

Large-scale sequence analysis of avian influenza isolates.

21 January 2018

1 reference

IFNbeta induction by influenza A virus is mediated by RIG-I which is regulated by the viral NS1 protein

21 January 2018

1 reference

Influenza A virus inhibits type I IFN signaling via NF-kappaB-dependent induction of SOCS-3 expression

21 January 2018

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RIG-I-mediated antiviral responses to single-stranded RNA bearing 5'-phosphates

21 January 2018

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Inhibition of influenza virus-induced NF-kappaB and Raf/MEK/ERK activation can reduce both virus titers and cytokine expression simultaneously in vitro and in vivo

21 January 2018

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Birds and influenza H5NI virus movement to and within North America

21 January 2018

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The influenza virus enigma

21 January 2018

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Essential impact of NF-kappaB signaling on the H5N1 influenza A virus-induced transcriptome

21 January 2018

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IKKalpha controls p52/RelB at the skp2 gene promoter to regulate G1- to S-phase progression.

21 January 2018

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Cellular microRNAs inhibit replication of the H1N1 influenza A virus in infected cells

21 January 2018

1 reference

The language of covalent histone modifications

21 January 2018

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Epstein-Barr virus-encoded EBNA1 inhibits the canonical NF-kappaB pathway in carcinoma cells by inhibiting IKK phosphorylation

21 January 2018

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Transcriptional profiling of IKK2/NF-kappa B- and p38 MAP kinase-dependent gene expression in TNF-alpha-stimulated primary human endothelial cells

21 January 2018

1 reference

MRP8/MRP14 impairs endothelial integrity and induces a caspase-dependent and -independent cell death program

21 January 2018

1 reference

Apoptosis and proinflammatory cytokine responses of primary mouse microglia and astrocytes induced by human H1N1 and avian H5N1 influenza viruses

21 January 2018

1 reference

Influenza A virus NS1 protein prevents activation of NF-kappaB and induction of alpha/beta interferon

21 January 2018

1 reference

Functional replacement of the carboxy-terminal two-thirds of the influenza A virus NS1 protein with short heterologous dimerization domains.

21 January 2018

1 reference

Wet markets--a continuing source of severe acute respiratory syndrome and influenza?

21 January 2018

1 reference

NFkappaB negatively regulates interferon-induced gene expression and anti-influenza activity.

21 January 2018

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Caspase 3 activation is essential for efficient influenza virus propagation

21 January 2018

1 reference

NF-kappaB-dependent induction of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and Fas/FasL is crucial for efficient influenza virus propagation

21 January 2018

1 reference

NF-kappaB-inducing kinase regulates the processing of NF-kappaB2 p100

21 January 2018

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Histone H3 phosphorylation by IKK-alpha is critical for cytokine-induced gene expression

21 January 2018

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Inhibition of NF-kappa-B cellular function via specific targeting of the I-kappa-B-ubiquitin ligase

21 January 2018

1 reference

Control of apoptosis in influenza virus-infected cells by up-regulation of Akt and p53 signaling

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1111/CMI.12005

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10 September 2017

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