(Q39312205)

10 September 2017

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title

Non-homologous DNA end joining and alternative pathways to double-strand break repair (English)

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10 September 2017

Howard H Y Chang

1

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10 September 2017

Nicholas R Pannunzio

series ordinal

2

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10 September 2017

Noritaka Adachi

series ordinal

3

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10 September 2017

Michael R Lieber

series ordinal

4

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10 September 2017

17 May 2017

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Nature Reviews Molecular Cell Biology

10 September 2017

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10 September 2017

18

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10 September 2017

495-506

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10 September 2017

8

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https://scigraph.springernature.com/pub.10.1038/nrm.2017.48

10 September 2017

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cites work

The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway

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Ageing, repetitive genomes and DNA damage

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DNA-PK: the means to justify the ends?

31 March 2020

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Different DNA End Configurations Dictate Which NHEJ Components Are Most Important for Joining Efficiency.

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRM.2017.48

DNA-PK autophosphorylation facilitates Artemis endonuclease activity

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRM.2017.48

DNA-PKcs regulates a single-stranded DNA endonuclease activity of Artemis

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRM.2017.48

Unifying the DNA end-processing roles of the artemis nuclease: Ku-dependent artemis resection at blunt DNA ends

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Structure-Specific nuclease activities of Artemis and the Artemis: DNA-PKcs complex

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Nucleases of the metallo-beta-lactamase family and their role in DNA and RNA metabolism

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Evidence that the DNA endonuclease ARTEMIS also has intrinsic 5'-exonuclease activity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Artemis, a novel DNA double-strand break repair/V(D)J recombination protein, is mutated in human severe combined immune deficiency.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Hairpin opening and overhang processing by an Artemis/DNA-dependent protein kinase complex in nonhomologous end joining and V(D)J recombination

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

DNA-PKcs dependence of Artemis endonucleolytic activity, differences between hairpins and 5' or 3' overhangs

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Autoinhibition of the Nuclease ARTEMIS Is Mediated by a Physical Interaction between Its Catalytic and C-terminal Domains.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Artemis C-terminal region facilitates V(D)J recombination through its interactions with DNA Ligase IV and DNA-PKcs

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Structural Basis of DNA Ligase IV-Artemis Interaction in Nonhomologous End-Joining

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

A pathway of double-strand break rejoining dependent upon ATM, Artemis, and proteins locating to gamma-H2AX foci.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

The requirement of Artemis in double-strand break repair depends on the type of DNA damage.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

A novel human AP endonuclease with conserved zinc-finger-like motifs involved in DNA strand break responses

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Polynucleotide kinase and aprataxin-like forkhead-associated protein (PALF) acts as both a single-stranded DNA endonuclease and a single-stranded DNA 3' exonuclease and can participate in DNA end joining in a biochemical system

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

APLF promotes the assembly and activity of non-homologous end joining protein complexes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Non-homologous end joining often uses microhomology: implications for alternative end joining

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Structure-function studies of DNA polymerase λ

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Sustained active site rigidity during synthesis by human DNA polymerase μ

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

A biochemically defined system for mammalian nonhomologous DNA end joining

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Nonoverlapping functions of DNA polymerases mu, lambda, and terminal deoxynucleotidyltransferase during immunoglobulin V(D)J recombination in vivo

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Essential role for polymerase specialization in cellular nonhomologous end joining.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Polymerase mu is a DNA-directed DNA/RNA polymerase

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

A gradient of template dependence defines distinct biological roles for family X polymerases in nonhomologous end joining

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

XRCC4:DNA ligase IV can ligate incompatible DNA ends and can ligate across gaps

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

The polymerases for V(D)J recombination

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

DNA joint dependence of pol X family polymerase action in nonhomologous end joining

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Nonhomologous end joining in yeast

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Rejoining of DNA double-strand breaks as a function of overhang length

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Evidence that base stacking potential in annealed 3' overhangs determines polymerase utilization in yeast nonhomologous end joining

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Activity of DNA ligase IV stimulated by complex formation with XRCC4 protein in mammalian cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Nonhomologous end joining and V(D)J recombination require an additional factor

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

XLF interacts with the XRCC4-DNA ligase IV complex to promote DNA nonhomologous end-joining

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Cernunnos, a novel nonhomologous end-joining factor, is mutated in human immunodeficiency with microcephaly

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Sliding sleeves of XRCC4-XLF bridge DNA and connect fragments of broken DNA.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

DNA repair. PAXX, a paralog of XRCC4 and XLF, interacts with Ku to promote DNA double-strand break repair

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Interactome analysis identifies a new paralogue of XRCC4 in non-homologous end joining DNA repair pathway

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

XRCC4/XLF Interaction Is Variably Required for DNA Repair and Is Not Required for Ligase IV Stimulation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

PAXX Is an Accessory c-NHEJ Factor that Associates with Ku70 and Has Overlapping Functions with XLF.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

The molecular architecture of the mammalian DNA repair enzyme, polynucleotide kinase

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

The neurodegenerative disease protein aprataxin resolves abortive DNA ligation intermediates

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Xrcc4 physically links DNA end processing by polynucleotide kinase to DNA ligation by DNA ligase IV

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Conversion of phosphoglycolate to phosphate termini on 3' overhangs of DNA double strand breaks by the human tyrosyl-DNA phosphodiesterase hTdp1

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

GC/MS methods to quantify the 2-deoxypentos-4-ulose and 3'-phosphoglycolate pathways of 4' oxidation of 2-deoxyribose in DNA: application to DNA damage produced by gamma radiation and bleomycin

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Deficiency in 3'-phosphoglycolate processing in human cells with a hereditary mutation in tyrosyl-DNA phosphodiesterase (TDP1)

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

DNA structure, mutations, and human genetic disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Interaction of the Ku heterodimer with the DNA ligase IV/Xrcc4 complex and its regulation by DNA-PK.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Crystal structure of an Xrcc4-DNA ligase IV complex

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Requirement for an interaction of XRCC4 with DNA ligase IV for wild-type V(D)J recombination and DNA double-strand break repair in vivo.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

DNA ligase IV binds to XRCC4 via a motif located between rather than within its BRCT domains

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Ku recruits the XRCC4-ligase IV complex to DNA ends

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Saccharomyces cerevisiae LIF1: a function involved in DNA double-strand break repair related to mammalian XRCC4.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Blunt-ended DNA double-strand breaks induced by endonucleases PvuII and EcoRV are poor substrates for repair in Saccharomyces cerevisiae.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Crystal structure of DNA-PKcs reveals a large open-ring cradle comprised of HEAT repeats

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

DNA-PKcs structure suggests an allosteric mechanism modulating DNA double-strand break repair.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Productive and nonproductive complexes of Ku and DNA-dependent protein kinase at DNA termini

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Three-Dimensional Structure of the Human DNA-PKcs/Ku70/Ku80 Complex Assembled on DNA and Its Implications for DNA DSB Repair

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

The DNA-dependent protein kinase catalytic subunit phosphorylation sites in human Artemis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

A biochemically defined system for coding joint formation in V(D)J recombination

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Effects of base sequence on the loop folding in DNA hairpins

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Processing of damaged DNA ends for double-strand break repair in mammalian cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Regulation and mechanisms of mammalian double-strand break repair

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Processing of 3'-phosphoglycolate-terminated DNA double strand breaks by Artemis nuclease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Coordinate 5' and 3' endonucleolytic trimming of terminally blocked blunt DNA double-strand break ends by Artemis nuclease and DNA-dependent protein kinase

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Structure of the Catalytic Region of DNA Ligase IV in Complex with an Artemis Fragment Sheds Light on Double-Strand Break Repair

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Structural insight into the substrate specificity of DNA Polymerase mu

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Crystal structure of the Xrcc4 DNA repair protein and implications for end joining

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Crystal structure of human XLF: a twist in nonhomologous DNA end-joining

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Cernunnos/XLF promotes the ligation of mismatched and noncohesive DNA ends

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

PAXX promotes KU accumulation at DNA breaks and is essential for end-joining in XLF-deficient mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Synthetic lethality between PAXX and XLF in mammalian development

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Specific Roles of XRCC4 Paralogs PAXX and XLF during V(D)J Recombination.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

PAXX and XLF DNA repair factors are functionally redundant in joining DNA breaks in a G1-arrested progenitor B-cell line

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Mutations in XRCC4 cause primordial dwarfism without causing immunodeficiency.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Mechanistic constraints on diversity in human V(D)J recombination

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Regulation of Single-Strand Annealing and its Role in Genome Maintenance

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Cell biology of mitotic recombination

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Mating-type gene switching in Saccharomyces cerevisiae

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Ku prevents Exo1 and Sgs1-dependent resection of DNA ends in the absence of a functional MRX complex or Sae2

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

A cell cycle-dependent regulatory circuit composed of 53BP1-RIF1 and BRCA1-CtIP controls DNA repair pathway choice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Biochemical mechanism of DSB end resection and its regulation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Distinct roles of chromatin-associated proteins MDC1 and 53BP1 in mammalian double-strand break repair

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

A Polymerase Theta-dependent repair pathway suppresses extensive genomic instability at endogenous G4 DNA sites

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

DNA polymerase θ (POLQ), double-strand break repair, and cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Essential Roles for Polymerase θ-Mediated End Joining in the Repair of Chromosome Breaks

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Dual roles for DNA polymerase theta in alternative end-joining repair of double-strand breaks in Drosophila

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Polymerase θ is a robust terminal transferase that oscillates between three different mechanisms during end-joining

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Mammalian polymerase θ promotes alternative NHEJ and suppresses recombination

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Mechanism of suppression of chromosomal instability by DNA polymerase POLQ

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Human DNA ligases I, III, and IV-purification and new specific assays for these enzymes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Altered kinetics of nonhomologous end joining and class switch recombination in ligase IV-deficient B cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Redundant function of DNA ligase 1 and 3 in alternative end-joining during immunoglobulin class switch recombination

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Microhomology-Mediated End Joining: A Back-up Survival Mechanism or Dedicated Pathway?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Catalytic and noncatalytic roles of the CtIP endonuclease in double-strand break end resection

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Phosphorylated CtIP Functions as a Co-factor of the MRE11-RAD50-NBS1 Endonuclease in DNA End Resection.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Nbs1 Converts the Human Mre11/Rad50 Nuclease Complex into an Endo/Exonuclease Machine Specific for Protein-DNA Adducts.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Parp1 facilitates alternative NHEJ, whereas Parp2 suppresses IgH/c-myc translocations during immunoglobulin class switch recombination

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

DNA polymerases and cancer.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Synthesis-dependent microhomology-mediated end joining accounts for multiple types of repair junctions

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Lymphoid V(D)J recombination: nucleotide insertion at signal joints as well as coding joints

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Mechanisms of human lymphoid chromosomal translocations

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

The t(14;18)(q32;q21)/IGH-MALT1 translocation in MALT lymphomas contains templated nucleotide insertions and a major breakpoint region similar to follicular and mantle cell lymphoma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Impact of DNA ligase IV on nonhomologous end joining pathways during class switch recombination in human cells.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Repair Pathway Choices and Consequences at the Double-Strand Break

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Contribution of canonical nonhomologous end joining to chromosomal rearrangements is enhanced by ATM kinase deficiency

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Mechanism and regulation of DNA end resection in eukaryotes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Sae2, Exo1 and Sgs1 collaborate in DNA double-strand break processing

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Sgs1 helicase and two nucleases Dna2 and Exo1 resect DNA double-strand break ends

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Rad51 recombinase and recombination mediators

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Two pathways for removal of nonhomologous DNA ends during double-strand break repair in Saccharomyces cerevisiae

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

RAD59 is required for efficient repair of simultaneous double-strand breaks resulting in translocations in Saccharomyces cerevisiae

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

DNA end resection, homologous recombination and DNA damage checkpoint activation require CDK1

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Human CtIP mediates cell cycle control of DNA end resection and double strand break repair

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Cell cycle-dependent complex formation of BRCA1.CtIP.MRN is important for DNA double-strand break repair.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Sae2 promotes dsDNA endonuclease activity within Mre11-Rad50-Xrs2 to resect DNA breaks

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Cell cycle regulation of DNA double-strand break end resection by Cdk1-dependent Dna2 phosphorylation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Phosphorylation of EXO1 by CDKs 1 and 2 regulates DNA end resection and repair pathway choice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Regulation of the DNA Damage Response by DNA-PKcs Inhibitory Phosphorylation of ATM.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

ATM and Artemis promote homologous recombination of radiation-induced DNA double-strand breaks in G2

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

DNA Double-Strand Break Resection Occurs during Non-homologous End Joining in G1 but Is Distinct from Resection during Homologous Recombination

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Chromosomal translocations in human cells are generated by canonical nonhomologous end-joining.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Alternative end-joining catalyzes robust IgH locus deletions and translocations in the combined absence of ligase 4 and Ku70

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Mechanisms that promote and suppress chromosomal translocations in lymphocytes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Genome-wide translocation sequencing reveals mechanisms of chromosome breaks and rearrangements in B cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Congenital defects in V(D)J recombination

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

A founder mutation in Artemis, an SNM1-like protein, causes SCID in Athabascan-speaking Native Americans

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

DCLRE1C (ARTEMIS) mutations causing phenotypes ranging from atypical severe combined immunodeficiency to mere antibody deficiency.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

The clinical impact of deficiency in DNA non-homologous end-joining

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

When natural mutants do not fit our expectations: the intriguing case of patients with XRCC4 mutations revealed by whole-exome sequencing

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

XLF deficiency results in reduced N-nucleotide addition during V(D)J recombination.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

PRKDC mutations in a SCID patient with profound neurological abnormalities

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

PRKDC mutations associated with immunodeficiency, granuloma, and autoimmune regulator-dependent autoimmunity.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Mechanisms underlying structural variant formation in genomic disorders

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Analysis of deletion breakpoints from 1,092 humans reveals details of mutation mechanisms

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Massive genomic rearrangement acquired in a single catastrophic event during cancer development

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

APLF (C2orf13) is a novel human protein involved in the cellular response to chromosomal DNA strand breaks

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Solution structures of the two PBZ domains from human APLF and their interaction with poly(ADP-ribose)

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

Structure and identification of ADP-ribose recognition motifs of APLF and role in the DNA damage response

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

DNA repair factor APLF is a histone chaperone

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRM.2017.48

EBP-80, a transcription factor closely resembling the human autoantigen Ku, recognizes single- to double-strand transitions in DNA.

31 March 2020

1 reference

12 December 2020

gamma Ray induced deoxyribonucleic acid strand breaks. 3' Glycolate termini

1 reference

12 December 2020

Templated nucleotide addition and immunoglobulin JH-gene utilization in t(11;14) junctions: implications for the mechanism of translocation and the origin of mantle cell lymphoma

1 reference

12 December 2020

Enzyme action at 3' termini of ionizing radiation-induced DNA strand breaks

1 reference

12 December 2020

Increased chromosomal aberrations in first metaphases of cells isolated from the kidneys of aged mice

1 reference

12 December 2020

Mechanism of interaction between Ku protein and DNA

1 reference

12 December 2020

A DNA-PKcs mutation in a radiosensitive T-B- SCID patient inhibits Artemis activation and nonhomologous end-joining.

1 reference

12 December 2020

Follicular lymphomas' BCL-2/IgH junctions contain templated nucleotide insertions: novel insights into the mechanism of t(14;18) translocation.

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRM.2017.48

1 reference

10 September 2017

1 reference