(Q39317127)

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Inhibition of intracellular antiviral defense mechanisms augments lentiviral transduction of human natural killer cells: implications for gene therapy.

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22779406%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

Inhibition of intracellular antiviral defense mechanisms augments lentiviral transduction of human natural killer cells: implications for gene therapy (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22779406%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

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6

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7 February 2020

1

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7 February 2020

author name string

Sanna Nyström

2

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7 February 2020

Mari Gilljam

3

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7 February 2020

Birgitta Stellan

4

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7 February 2020

Steven E Applequist

5

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7 February 2020

publication date

10 September 2012

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7 February 2020

Human Gene Therapy

1 reference

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22779406%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

23

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7 February 2020

10

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7 February 2020

1090-1100

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Europe PubMed Central

PMC publication ID

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7 February 2020

Nucleic acid sensing at the interface between innate and adaptive immunity in vaccination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3472531

11 September 2017

Use of allogeneic NK cells for cancer immunotherapy.

1 reference

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11 September 2017

IL-2 family cytokines: new insights into the complex roles of IL-2 as a broad regulator of T helper cell differentiation

1 reference

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11 September 2017

Clinical cancer therapy by NK cells via antibody-dependent cell-mediated cytotoxicity

1 reference

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11 September 2017

Natural killer cell activation secondary to innate pattern sensing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3472531

11 September 2017

Natural killer cell responses to viral infection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3472531

11 September 2017

Pathogen recognition by the innate immune system

1 reference

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11 September 2017

Emerging natural killer cell immunotherapies: large-scale ex vivo production of highly potent anticancer effectors

1 reference

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11 September 2017

Genetic modification of natural killer cells for adoptive cellular immunotherapy.

1 reference

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11 September 2017

Recognition of virus infection and innate host responses to viral gene therapy vectors

1 reference

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11 September 2017

Recognition of viruses by cytoplasmic sensors

1 reference

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11 September 2017

Natural killer cell-based immunotherapy in cancer: current insights and future prospects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3472531

11 September 2017

The TLR9-MyD88 pathway is critical for adaptive immune responses to adeno-associated virus gene therapy vectors in mice

1 reference

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11 September 2017

Engineering antigen-specific primary human NK cells against HER-2 positive carcinomas

1 reference

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11 September 2017

A multicolor panel of novel lentiviral "gene ontology" (LeGO) vectors for functional gene analysis.

1 reference

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11 September 2017

Evolutionary struggles between NK cells and viruses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3472531

11 September 2017

IL-21 mediates apoptosis through up-regulation of the BH3 family member BIM and enhances both direct and antibody-dependent cellular cytotoxicity in primary chronic lymphocytic leukemia cells in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3472531

11 September 2017

Interferons and viruses: an interplay between induction, signalling, antiviral responses and virus countermeasures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3472531

11 September 2017

Interleukin-21 activates human natural killer cells and modulates their surface receptor expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3472531

11 September 2017

Toll-like receptors, RIG-I-like RNA helicases and the antiviral innate immune response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3472531

11 September 2017

Insect baculoviruses strongly potentiate adaptive immune responses by inducing type I IFN

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3472531

11 September 2017

Silencing human NKG2D, DAP10, and DAP12 reduces cytotoxicity of activated CD8+ T cells and NK cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3472531

11 September 2017

Genetic modification of primary natural killer cells overcomes inhibitory signals and induces specific killing of leukemic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3472531

11 September 2017

Molecular basis of the inflammatory response to adenovirus vectors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3472531

11 September 2017

Differential activation of innate immune responses by adenovirus and adeno-associated virus vectors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3472531

11 September 2017

Altering the specificity of NK:target cell interactions by genetic manipulation of NK receptor expression on primary mouse NK cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3472531

14 September 2017

Introduction of shRNAs into primary NK cells with lentivirus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3472531

14 September 2017

Use of the pharmacological inhibitor BX795 to study the regulation and physiological roles of TBK1 and IkappaB kinase epsilon: a distinct upstream kinase mediates Ser-172 phosphorylation and activation

1 reference

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14 September 2017

Transfection with mRNA for CD19 specific chimeric antigen receptor restores NK cell mediated killing of CLL cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3472531

14 September 2017

Permanent silencing of NKG2A expression for cell-based therapeutics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3472531

14 September 2017

Delivery of DNA into natural killer cells for immunotherapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3472531

14 September 2017

High-efficient lentiviral vector-mediated gene transfer into primary human NK cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3472531

14 September 2017

Efficient infection of human natural killer cells with an EBV/retroviral hybrid vector.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3472531

14 September 2017

Cost efficient and effective gene transfer into the human natural killer cell line, NK92.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3472531

14 September 2017

Targeting IL-2 to the endoplasmic reticulum confines autocrine growth stimulation to NK-92 cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3472531

14 September 2017

Gene transfer into human T lymphocytes and natural killer cells by Ad5/F35 chimeric adenoviral vectors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3472531

14 September 2017

Characterization of interleukin-15 gene-modified human natural killer cells: implications for adoptive cellular immunotherapy.

1 reference

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14 September 2017

Rapid and highly efficient gene transfer into natural killer cells by nucleofection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3472531

14 September 2017

Helper-free HSV-1 amplicons elicit a markedly less robust innate immune response in the CNS.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3472531

14 September 2017

Retargeting of natural killer-cell cytolytic activity to ErbB2-expressing cancer cells results in efficient and selective tumor cell destruction.

1 reference

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25 September 2017

Lentiviral-mediated gene transfer into human lymphocytes: role of HIV-1 accessory proteins.

1 reference

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Gene transfer into stimulated and unstimulated T lymphocytes by HIV-1-derived lentiviral vectors.

1 reference

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25 September 2017

Stable transduction of the interleukin-2 gene into human natural killer cell lines and their phenotypic and functional characterization in vitro and in vivo.

1 reference

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Synergistic regulation of the human interleukin-12 p40 promoter by NFkappaB and Ets transcription factors in Epstein-Barr virus-transformed B cells and macrophages.

1 reference

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1 reference

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1 reference

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1 reference

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21 August 2018

Lentiviral vectors mediate stable and efficient gene delivery into primary murine natural killer cells

1 reference

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21 August 2018

In vivo administration of lentiviral vectors triggers a type I interferon response that restricts hepatocyte gene transfer and promotes vector clearance.

1 reference

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21 August 2018

Efficient gene transfer into primary human natural killer cells by retroviral transduction.

1 reference

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21 August 2018

Innate immune mechanisms dominate elimination of adenoviral vectors following in vivo administration.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3472531

21 August 2018

Retroviral gene transfer into primary human natural killer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22779406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of silencing NKG2D through RNA interference on receptor functions in interleukin-2-activated human natural killer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22779406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Early STAT1 activation after systemic delivery of HSV amplicon vectors suppresses transcription of the vector-encoded transgene

1 reference

https://pubmed.ncbi.nlm.nih.gov/22779406

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1089/HUM.2012.080

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22779406%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22779406%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22779406%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

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