(Q39320836)

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Quantitative structure-activity relationship studies on indenoisoquinoline topoisomerase I inhibitors as anticancer agents in human renal cell carcinoma cell line SN12C.

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scholarly article

1 reference

Europe PubMed Central

11 September 2017

Quantitative structure-activity relationship studies on indenoisoquinoline topoisomerase I inhibitors as anticancer agents in human renal cell carcinoma cell line SN12C. (English)

1 reference

Europe PubMed Central

11 September 2017

0 references

renal cell carcinoma

1 reference

based on heuristic

inferred from title

quantitative structure-activity relationship

1 reference

based on heuristic

inferred from title

author name string

Yi Zhi

1

1 reference

Europe PubMed Central

11 September 2017

Jin Yang

2

1 reference

Europe PubMed Central

11 September 2017

Shengchao Tian

3

1 reference

Europe PubMed Central

11 September 2017

Fang Yuan

4

1 reference

Europe PubMed Central

11 September 2017

Yang Liu

5

1 reference

Europe PubMed Central

11 September 2017

Yi Zhang

6

1 reference

Europe PubMed Central

11 September 2017

Pinghua Sun

7

1 reference

Europe PubMed Central

11 September 2017

Bo Song

8

1 reference

Europe PubMed Central

11 September 2017

Zhiwen Chen

9

1 reference

Europe PubMed Central

11 September 2017

language of work or name

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publication date

18 May 2012

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Europe PubMed Central

11 September 2017

International Journal of Molecular Sciences

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Europe PubMed Central

11 September 2017

13

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Europe PubMed Central

11 September 2017

6009-6025

1 reference

Europe PubMed Central

11 September 2017

5

1 reference

Europe PubMed Central

11 September 2017

copyright license

Creative Commons Attribution 4.0 International

18 May 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

3D-QSAR studies on thiazolidin-4-one S1P₁receptor agonists by CoMFA and CoMSIA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382809

11 September 2017

7-azaindenoisoquinolines as topoisomerase I inhibitors and potential anticancer agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382809

11 September 2017

The epidemiology of renal cell carcinoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382809

11 September 2017

Design, Synthesis, and Evaluation of Dibenzo[c,h][1,6]naphthyridines as Topoisomerase I Inhibitors and Potential Anticancer Agents

1 reference

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11 September 2017

Cancer statistics, 2010

1 reference

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11 September 2017

DNA Topoisomerase I Inhibitors: Chemistry, Biology, and Interfacial Inhibition

1 reference

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11 September 2017

Novel indenoisoquinolines NSC 725776 and NSC 724998 produce persistent topoisomerase I cleavage complexes and overcome multidrug resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382809

11 September 2017

Synthesis and Evaluation of Indenoisoquinoline Topoisomerase I Inhibitors Substituted with Nitrogen Heterocycles

1 reference

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11 September 2017

Topoisomerase I inhibitors: camptothecins and beyond

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382809

11 September 2017

IPM chemotherapy in cytokine refractory renal cell cancer

1 reference

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Cellular roles of dna topoisomerases: a molecular perspective

1 reference

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11 September 2017

1 reference

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Survival and prognostic stratification of 670 patients with advanced renal cell carcinoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382809

11 September 2017

Comparative molecular similarity index analysis (CoMSIA) to study hydrogen-bonding properties and to score combinatorial libraries

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382809

11 September 2017

Topotecan and small interfering RNA suppress survivin expression synergistically in Caki-1 renal cancer cells: Direct suppression of survivin and enhancement of transfection efficiency by topotecan.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382809

14 September 2017

Nitrated indenoisoquinolines as topoisomerase I inhibitors: a systematic study and optimization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382809

14 September 2017

Synergistic effect of survivin-specific small interfering RNA and topotecan in renal cancer cells: topotecan enhances liposome-mediated transfection by increasing cellular uptake.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382809

14 September 2017

Cross-validated R2-guided region selection for comparative molecular field analysis: a simple method to achieve consistent results

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382809

25 September 2017

Topotecan (Hycamtin) responsiveness in human renal carcinoma cell lines of the clear cell and papillary types

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382809

17 June 2018

Clinical applications of the camptothecins.

1 reference

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17 June 2018

Comparative molecular field analysis (CoMFA). 1. Effect of shape on binding of steroids to carrier proteins.

1 reference

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21 August 2018

Exploring QSARs for 5-lipoxygenase (5-LO) inhibitory activity of 2-substituted 5-hydroxyindole-3-carboxylates by CoMFA and CoMSIA.

1 reference

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21 August 2018

3D-QSAR studies on quinazoline antifolate thymidylate synthase inhibitors by CoMFA and CoMSIA models

1 reference

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21 August 2018

Friction and torque govern the relaxation of DNA supercoils by eukaryotic topoisomerase IB.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382809

21 August 2018

Design, synthesis, and biological evaluation of cytotoxic 11-alkenylindenoisoquinoline topoisomerase I inhibitors and indenoisoquinoline-camptothecin hybrids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3382809

21 August 2018

Plant Antitumor Agents. I. The Isolation and Structure of Camptothecin, a Novel Alkaloidal Leukemia and Tumor Inhibitor from Camptotheca acuminata1,2

1 reference

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21 January 2018

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1 reference

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Three-dimensional quantitative structure-activity relationship analyses using comparative molecular field analysis and comparative molecular similarity indices analysis to elucidate selectivity differences of inhibitors binding to trypsin, thrombin,

1 reference

https://pubmed.ncbi.nlm.nih.gov/22754346

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Sample-distance partial least squares: PLS optimized for many variables, with application to CoMFA

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https://pubmed.ncbi.nlm.nih.gov/22754346

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Quantitative structure-activity relationships of antineoplastic drugs: nitrosoureas and triazenoimidazoles

1 reference

https://pubmed.ncbi.nlm.nih.gov/22754346

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Recent advances in comparative molecular field analysis (CoMFA)

1 reference

https://pubmed.ncbi.nlm.nih.gov/22754346

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Mechanism of action of eukaryotic DNA topoisomerase I and drugs targeted to the enzyme

1 reference

https://pubmed.ncbi.nlm.nih.gov/22754346

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.3390/IJMS13056009

1 reference

Europe PubMed Central

11 September 2017

1 reference

Europe PubMed Central

11 September 2017

1 reference

Europe PubMed Central

11 September 2017

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