(Q39327981)

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Activation of mitochondrial apoptosis pathways in cutaneous squamous cell carcinoma cells by diclofenac/hyaluronic acid is related to upregulation of Bad as well as downregulation of Mcl-1 and Bcl-w

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scholarly article

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Europe PubMed Central

PubMed publication ID

11 September 2017

Activation of mitochondrial apoptosis pathways in cutaneous squamous cell carcinoma cells by diclofenac/hyaluronic acid is related to upregulation of Bad as well as downregulation of Mcl-1 and Bcl-w (English)

1 reference

Europe PubMed Central

PubMed publication ID

11 September 2017

apoptotic process

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inferred from title

Eggert Stockfleth

3

object named as

Eggert Stockfleth

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Europe PubMed Central

PubMed publication ID

11 September 2017

author name string

Paul M Rodust

1

1 reference

Europe PubMed Central

PubMed publication ID

11 September 2017

Lothar F Fecker

2

1 reference

Europe PubMed Central

PubMed publication ID

11 September 2017

Jürgen Eberle

4

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Europe PubMed Central

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11 September 2017

publication date

1 July 2012

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Europe PubMed Central

PubMed publication ID

11 September 2017

Experimental Dermatology

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Europe PubMed Central

PubMed publication ID

11 September 2017

21

1 reference

Europe PubMed Central

PubMed publication ID

11 September 2017

7

1 reference

Europe PubMed Central

PubMed publication ID

11 September 2017

520-525

1 reference

Europe PubMed Central

PubMed publication ID

11 September 2017

Epidemiology of nonmelanoma skin cancer (NMSC) in Europe: accurate and comparable data are needed for effective public health monitoring and interventions

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01516.X

21 January 2018

Actinic keratosis is an early in situ squamous cell carcinoma: a proposal for reclassification.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01516.X

21 January 2018

Effective photodynamic therapy of actinic keratoses on the head and face with a novel, self-adhesive 5-aminolaevulinic acid patch

1 reference

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21 January 2018

Epidermal growth factor receptor gene numerical aberrations are frequent events in actinic keratoses and invasive cutaneous squamous cell carcinomas.

1 reference

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21 January 2018

Apoptosis pathways as promising targets for skin cancer therapy

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01516.X

21 January 2018

Differential expression of cell survival and cell cycle regulatory proteins in cutaneous squamoproliferative lesions

1 reference

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21 January 2018

Lymphocyte-mediated cytotoxicity.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01516.X

21 January 2018

Death receptor signaling

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01516.X

21 January 2018

Extrinsic versus intrinsic apoptosis pathways in anticancer chemotherapy

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01516.X

21 January 2018

Mitochondria and cell death: outer membrane permeabilization and beyond

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01516.X

21 January 2018

Apoptosis induction by Bcl-2 proteins independent of the BH3 domain

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01516.X

21 January 2018

The BCL-2 family reunion

1 reference

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21 January 2018

Overcoming apoptosis deficiency of melanoma-hope for new therapeutic approaches

1 reference

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21 January 2018

Cyclooxygenase-2 expression in murine and human nonmelanoma skin cancers: implications for therapeutic approaches

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01516.X

21 January 2018

The role of apoptosis in therapy and prophylaxis of epithelial tumours by nonsteroidal anti-inflammatory drugs (NSAIDs).

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01516.X

21 January 2018

UV-induced squamous cell carcinoma--a role for antiapoptotic signalling pathways

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01516.X

21 January 2018

Open label randomized study comparing 3 months vs. 6 months treatment of actinic keratoses with 3% diclofenac in 2.5% hyaluronic acid gel: a trial of the German Dermatologic Cooperative Oncology Group.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01516.X

21 January 2018

Enhanced death ligand-induced apoptosis in cutaneous SCC cells by treatment with diclofenac/hyaluronic acid correlates with downregulation of c-FLIP.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01516.X

21 January 2018

Analysis of apoptosis by propidium iodide staining and flow cytometry

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01516.X

21 January 2018

Topical diclofenac in the treatment of actinic keratoses

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01516.X

21 January 2018

The role of cyclooxygenase-2 in cell proliferation and cell death in human malignancies.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01516.X

21 January 2018

Time-course evaluation and treatment of skin inflammatory immune response after ultraviolet B irradiation

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01516.X

21 January 2018

Aspirin induces apoptosis in human leukemia cells independently of NF-kappaB and MAPKs through alteration of the Mcl-1/Noxa balance

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01516.X

21 January 2018

Anti-apoptotic Bcl-2 fails to form efficient complexes with pro-apoptotic Bak to protect from Celecoxib-induced apoptosis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01516.X

21 January 2018

Diclofenac induces apoptosis in hepatocytes by alteration of mitochondrial function and generation of ROS.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01516.X

21 January 2018

Inhibition of 12-LOX and COX-2 reduces the proliferation of human epidermoid carcinoma cells (A431) by modulating the ERK and PI3K-Akt signalling pathways

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01516.X

21 January 2018

Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01516.X

21 January 2018

Mcl-1 functions as major epidermal survival protein required for proper keratinocyte differentiation

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01516.X

21 January 2018

Endogenous Bak inhibitors Mcl-1 and Bcl-xL: differential impact on TRAIL resistance in Bax-deficient carcinoma.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01516.X

21 January 2018

Acquired activation of the Akt/cyclooxygenase-2/Mcl-1 pathway renders lung cancer cells resistant to apoptosis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01516.X

21 January 2018

Cyclooxygenase-2 (COX-2)-independent anticarcinogenic effects of selective COX-2 inhibitors

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01516.X

21 January 2018

Bcl-w forms complexes with Bax and Bak, and elevated ratios of Bax/Bcl-w and Bak/Bcl-w correspond to spermatogonial and spermatocyte apoptosis in the testis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01516.X

21 January 2018

Cyclooxygenase-2 inhibitor celecoxib augments chemotherapeutic drug-induced apoptosis by enhancing activation of caspase-3 and -9 in prostate cancer cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01516.X

21 January 2018

Increased cyclooxygenase-2 (COX-2): a potential role in the pathogenesis of lymphoma

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01516.X

21 January 2018

The proapoptotic BH3-only protein Bim is downregulated in a subset of colorectal cancers and is repressed by antiapoptotic COX-2/PGE(2) signalling in colorectal adenoma cells.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01516.X

21 January 2018

Diclofenac, a non-steroidal anti-inflammatory drug, suppresses apoptosis induced by endoplasmic reticulum stresses by inhibiting caspase signaling

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01516.X

21 January 2018

The cyclooxygenase-2 inhibitor nimesulide, a nonsteroidal analgesic, decreases the effect of radiation therapy in head-and-neck cancer cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01516.X

21 January 2018

Nonsteroidal anti-inflammatory drugs induce apoptosis in cutaneous T-cell lymphoma cells and enhance their sensitivity for TNF-related apoptosis-inducing ligand

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-0625.2012.01516.X

21 January 2018

Diclofenac inhibits tumor necrosis factor-α-induced nuclear factor-κB activation causing synergistic hepatocyte apoptosis

1 reference

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21 January 2018

The non-steroidal anti-inflammatory drugs Sulindac sulfide and Diclofenac induce apoptosis and differentiation in human acute myeloid leukemia cells through an AP-1 dependent pathway.

1 reference

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21 January 2018

Identifiers

10.1111/J.1600-0625.2012.01516.X

1 reference

Europe PubMed Central

PubMed publication ID

11 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

11 September 2017

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