(Q39335656)

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Targeting p90 ribosomal S6 kinase eliminates tumor-initiating cells by inactivating Y-box binding protein-1 in triple-negative breast cancers

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Europe PubMed Central

PubMed publication ID

11 September 2017

Targeting p90 ribosomal S6 kinase eliminates tumor-initiating cells by inactivating Y-box binding protein-1 in triple-negative breast cancers (English)

1 reference

Europe PubMed Central

PubMed publication ID

11 September 2017

Christopher J Lord

10

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Europe PubMed Central

PubMed publication ID

11 September 2017

object named as

Cristin G Print

12

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object named as

Alan Ashworth

1 reference

Europe PubMed Central

PubMed publication ID

11 September 2017

5

object named as

Rachel Brough

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Europe PubMed Central

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11 September 2017

Jessica R Frankum

6

object named as

Jessica Frankum

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Europe PubMed Central

PubMed publication ID

11 September 2017

author name string

Anna L Stratford

1

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Europe PubMed Central

PubMed publication ID

11 September 2017

Kristen Reipas

2

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Europe PubMed Central

PubMed publication ID

11 September 2017

Kaiji Hu

3

1 reference

Europe PubMed Central

PubMed publication ID

11 September 2017

Abbas Fotovati

4

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Europe PubMed Central

PubMed publication ID

11 September 2017

Mandeep Takhar

7

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Europe PubMed Central

PubMed publication ID

11 September 2017

Peter Watson

8

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Europe PubMed Central

PubMed publication ID

11 September 2017

Annette Lasham

11

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Europe PubMed Central

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11 September 2017

Sandra E Dunn

13

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11 September 2017

publication date

1 July 2012

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Europe PubMed Central

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11 September 2017

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Europe PubMed Central

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11 September 2017

30

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11 September 2017

7

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11 September 2017

1338-1348

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11 September 2017

Triple-negative breast cancer: clinical features and patterns of recurrence

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https://api.crossref.org/works/10.1002%2FSTEM.1128

21 January 2018

Response to neoadjuvant therapy and long-term survival in patients with triple-negative breast cancer

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https://api.crossref.org/works/10.1002%2FSTEM.1128

21 January 2018

The CD44+/CD24- phenotype is enriched in basal-like breast tumors

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https://api.crossref.org/works/10.1002%2FSTEM.1128

21 January 2018

Breast cancer cell lines contain functional cancer stem cells with metastatic capacity and a distinct molecular signature

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https://api.crossref.org/works/10.1002%2FSTEM.1128

21 January 2018

Breast cancer stem cells and intrinsic subtypes: controversies rage on.

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https://api.crossref.org/works/10.1002%2FSTEM.1128

21 January 2018

Heterogeneity for stem cell-related markers according to tumor subtype and histologic stage in breast cancer.

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https://api.crossref.org/works/10.1002%2FSTEM.1128

21 January 2018

Residual breast cancers after conventional therapy display mesenchymal as well as tumor-initiating features

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1128

21 January 2018

Intrinsic resistance of tumorigenic breast cancer cells to chemotherapy

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https://api.crossref.org/works/10.1002%2FSTEM.1128

21 January 2018

The response of CD24(-/low)/CD44+ breast cancer-initiating cells to radiation

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https://api.crossref.org/works/10.1002%2FSTEM.1128

21 January 2018

Human breast cancer cell lines contain stem-like cells that self-renew, give rise to phenotypically diverse progeny and survive chemotherapy

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1128

21 January 2018

Y-box binding protein-1 induces the expression of CD44 and CD49f leading to enhanced self-renewal, mammosphere growth, and drug resistance

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1128

21 January 2018

Targeting tumour-initiating cells to improve the cure rates for triple-negative breast cancer.

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1128

21 January 2018

Survival of mammary stem cells in suspension culture: implications for stem cell biology and neoplasia

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1128

21 January 2018

Isolation and in vitro propagation of tumorigenic breast cancer cells with stem/progenitor cell properties

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https://api.crossref.org/works/10.1002%2FSTEM.1128

21 January 2018

Gene set enrichment analysis provides insight into novel signalling pathways in breast cancer stem cells

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1128

21 January 2018

Epithelial mesenchymal transition traits in human breast cancer cell lines parallel the CD44(hi/)CD24 (lo/-) stem cell phenotype in human breast cancer

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1128

21 January 2018

Molecular definition of breast tumor heterogeneity

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1128

21 January 2018

The RSK factors of activating the Ras/MAPK signaling cascade

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1128

21 January 2018

FGFR3 activates RSK2 to mediate hematopoietic transformation through tyrosine phosphorylation of RSK2 and activation of the MEK/ERK pathway

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1128

21 January 2018

Phosphorylated insulin-like growth factor-i/insulin receptor is present in all breast cancer subtypes and is related to poor survival.

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1128

21 January 2018

Y-box binding protein-1 serine 102 is a downstream target of p90 ribosomal S6 kinase in basal-like breast cancer cells

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1128

21 January 2018

The RSK family of kinases: emerging roles in cellular signalling

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1128

21 January 2018

Phosphorylation of the c-Fos transrepression domain by mitogen-activated protein kinase and 90-kDa ribosomal S6 kinase

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1128

21 January 2018

Rsk1 mediates a MEK-MAP kinase cell survival signal

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1128

21 January 2018

Inactivation of glycogen synthase kinase-3 beta by phosphorylation: new kinase connections in insulin and growth-factor signalling

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1128

21 January 2018

Histone code pathway involving H3 S28 phosphorylation and K27 acetylation activates transcription and antagonizes polycomb silencing

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1128

21 January 2018

Requirement of Rsk-2 for epidermal growth factor-activated phosphorylation of histone H3

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1128

21 January 2018

The phosphoinositide-dependent kinase-1 inhibitor 2-amino-N-[4-[5-(2-phenanthrenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]phenyl]-acetamide (OSU-03012) prevents Y-box binding protein-1 from inducing epidermal growth factor receptor

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1128

21 January 2018

Functional viability profiles of breast cancer

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1128

21 January 2018

Disruption of the Y-box binding protein-1 results in suppression of the epidermal growth factor receptor and HER-2.

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1128

21 January 2018

YB-1, the E2F pathway, and regulation of tumor cell growth

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1128

21 January 2018

Strong time dependence of the 76-gene prognostic signature for node-negative breast cancer patients in the TRANSBIG multicenter independent validation series

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1128

21 January 2018

Molecular decoy to the Y-box binding protein-1 suppresses the growth of breast and prostate cancer cells whilst sparing normal cell viability

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1128

21 January 2018

Prolonged drug selection of breast cancer cells and enrichment of cancer stem cell characteristics

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1128

21 January 2018

Triple-Negative Breast Cancer

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1128

21 January 2018

Redefining prognostic factors for breast cancer: YB-1 is a stronger predictor of relapse and disease-specific survival than estrogen receptor or HER-2 across all tumor subtypes

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1128

21 January 2018

YB-1 evokes susceptibility to cancer through cytokinesis failure, mitotic dysfunction and HER2 amplification

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1128

21 January 2018

YB-1 bridges neural stem cells and brain tumor-initiating cells via its roles in differentiation and cell growth

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1128

21 January 2018

Y-box binding protein-1 promotes castration-resistant prostate cancer growth via androgen receptor expression.

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1128

21 January 2018

The hyaluronan receptors CD44 and Rhamm (CD168) form complexes with ERK1,2 that sustain high basal motility in breast cancer cells

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1128

21 January 2018

Fibroblast growth factor receptor 3 associates with and tyrosine phosphorylates p90 RSK2, leading to RSK2 activation that mediates hematopoietic transformation

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1128

21 January 2018

Targeting of CD44 eradicates human acute myeloid leukemic stem cells

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1128

21 January 2018

Hierarchical organization of prostate cancer cells in xenograft tumors: the CD44+alpha2beta1+ cell population is enriched in tumor-initiating cells

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1128

21 January 2018

Identification of pancreatic cancer stem cells

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1128

21 January 2018

Phenotypic characterization of human colorectal cancer stem cells

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1128

21 January 2018

The promise and challenges of targeting RSK for the treatment of cancer.

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1128

21 January 2018

p90 ribosomal S6 kinase 2 promotes invasion and metastasis of human head and neck squamous cell carcinoma cells

1 reference

https://api.crossref.org/works/10.1002%2FSTEM.1128

21 January 2018

Identifiers

10.1002/STEM.1128

1 reference

Europe PubMed Central

PubMed publication ID

11 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

11 September 2017

ResearchGate publication ID

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