(Q39375118)

11 September 2017

title

PKC-dependent phosphorylation of p27 at T198 contributes to p27 stabilization and cell cycle arrest (English)

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11 September 2017

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3

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11 September 2017

Marianna Scrima

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Carmela De Marco

object named as

Carmela De Marco

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author name string

Fernanda De Vita

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11 September 2017

Miriam Riccardi

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11 September 2017

Giuseppe Viglietto

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11 September 2017

publication date

15 April 2012

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11 September 2017

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11 September 2017

volume

11

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11 September 2017

issue

8

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11 September 2017

page(s)

1583-1592

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CDK inhibitors: positive and negative regulators of G1-phase progression

11 September 2017

cites work

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Cyclins and cyclin-dependent kinases: a biochemical view

21 January 2018

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Cyclin-dependent protein kinases: key regulators of the eukaryotic cell cycle

21 January 2018

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Regulation of the cyclin-dependent kinase inhibitor p27 by degradation and phosphorylation.

21 January 2018

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Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals

21 January 2018

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Regulation of G(1) cyclin-dependent kinases in the mammalian cell cycle

21 January 2018

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Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27

21 January 2018

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Interleukin-2-mediated elimination of the p27Kip1 cyclin-dependent kinase inhibitor prevented by rapamycin

21 January 2018

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Repression of p27kip1 synthesis by platelet-derived growth factor in BALB/c 3T3 cells

21 January 2018

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CDK inhibitors: cell cycle regulators and beyond

21 January 2018

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Duality of p27Kip1 function in tumorigenesis

21 January 2018

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p27Kip1 metabolism: a fascinating labyrinth

21 January 2018

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Cyclin E-CDK2 is a regulator of p27Kip1.

21 January 2018

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Phosphorylation-dependent degradation of the cyclin-dependent kinase inhibitor p27

21 January 2018

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Ubiquitination of p27 is regulated by Cdk-dependent phosphorylation and trimeric complex formation

21 January 2018

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SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27

21 January 2018

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p45SKP2 promotes p27Kip1 degradation and induces S phase in quiescent cells

21 January 2018

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p27(Kip1) ubiquitination and degradation is regulated by the SCF(Skp2) complex through phosphorylated Thr187 in p27

21 January 2018

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Targeted disruption of Skp2 results in accumulation of cyclin E and p27(Kip1), polyploidy and centrosome overduplication

21 January 2018

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The cell-cycle regulatory protein Cks1 is required for SCF(Skp2)-mediated ubiquitinylation of p27

21 January 2018

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A CDK-independent function of mammalian Cks1: targeting of SCF(Skp2) to the CDK inhibitor p27Kip1.

21 January 2018

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Akt-dependent phosphorylation of p27Kip1 promotes binding to 14-3-3 and cytoplasmic localization

21 January 2018

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Phosphorylation of p27Kip1 at Threonine 198 by p90 Ribosomal Protein S6 Kinases Promotes Its Binding to 14-3-3 and Cytoplasmic Localization

21 January 2018

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The energy sensing LKB1-AMPK pathway regulates p27(kip1) phosphorylation mediating the decision to enter autophagy or apoptosis

21 January 2018

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C-terminal phosphorylation controls the stability and function of p27kip1

21 January 2018

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p27Kip1 modulates cell migration through the regulation of RhoA activation.

21 January 2018

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Studies and perspectives of protein kinase C.

21 January 2018

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Effects of different kinases and phosphatases on nuclear and cytoplasmic maturation of bovine oocytes.

21 January 2018

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Activation of protein kinase C isozymes is associated with post-mitotic events in intestinal epithelial cells in situ

21 January 2018

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Protein kinase C and beyond

21 January 2018

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Activation mechanisms of protein kinase C: maturation, catalytic activation, and targeting

21 January 2018

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GPS: a novel group-based phosphorylation predicting and scoring method.

21 January 2018

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Requirement of p27Kip1 for restriction point control of the fibroblast cell cycle

21 January 2018

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Abrogation of p27Kip1 by cDNA antisense suppresses quiescence (G0 state) in fibroblasts

21 January 2018

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A pathway in quiescent cells that controls p27Kip1 stability, subcellular localization, and tumor suppression

21 January 2018

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The cyclin-dependent kinase inhibitor p27Kip1 is stabilized in G(0) by Mirk/dyrk1B kinase

21 January 2018

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A growth factor-dependent nuclear kinase phosphorylates p27(Kip1) and regulates cell cycle progression

21 January 2018

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Protein kinase C-alpha activity inversely modulates invasion and growth of intestinal cells

21 January 2018

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Protein kinase Cdelta signaling downstream of the EGF receptor mediates migration and invasiveness of prostate cancer cells

21 January 2018

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Protein kinase C alpha-dependent signaling mediates endometrial cancer cell growth and tumorigenesis

21 January 2018

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Nonmutagenic mechanisms in carcinogenesis: role of protein kinase C in signal transduction and growth control

21 January 2018

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Five of six protein kinase C isoenzymes present in normal mucosa show reduced protein levels during tumor development in the human colon.

21 January 2018

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Protein kinase C tissue localization in human colonic tumors suggests a role for adenoma growth control.

21 January 2018

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PKC isoforms: villains in colon cancer?

21 January 2018

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Colonocyte differentiation is associated with increased expression and altered distribution of protein kinase C isozymes

21 January 2018

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Protein kinase C isozymes in colon carcinogenesis: guilt by omission.

21 January 2018

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Protein kinase C isozyme-mediated cell cycle arrest involves induction of p21(waf1/cip1) and p27(kip1) and hypophosphorylation of the retinoblastoma protein in intestinal epithelial cells

21 January 2018

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Protein kinase C signaling mediates a program of cell cycle withdrawal in the intestinal epithelium

21 January 2018

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Involvement of the ERK signaling cascade in protein kinase C-mediated cell cycle arrest in intestinal epithelial cells

21 January 2018

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Protein kinase Cdelta inhibition of S-phase transition in capillary endothelial cells involves the cyclin-dependent kinase inhibitor p27(Kip1).

21 January 2018

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A role for protein kinase C delta in the differential sensitivity of MCF-7 and MDA-MB 231 human breast cancer cells to phorbol ester-induced growth arrest and p21(WAFI/CIP1) induction.

21 January 2018

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Regulation of airway smooth muscle cyclin D1 transcription by protein kinase C-delta

21 January 2018

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Phorbol ester-induced G1 phase arrest selectively mediated by protein kinase Cdelta-dependent induction of p21.

21 January 2018

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PKCalpha tumor suppression in the intestine is associated with transcriptional and translational inhibition of cyclin D1

21 January 2018

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Phorbol 12-myristate 13-acetate inhibits FRO anaplastic human thyroid cancer cell proliferation by inducing cell cycle arrest in G1/S phase: evidence for an effect mediated by PKCdelta

21 January 2018

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Key role of the cyclin-dependent kinase inhibitor p27kip1 for embryonal carcinoma cell survival and differentiation.

21 January 2018

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Protein Kinase C δ Inhibits the Proliferation of Vascular Smooth Muscle Cells by Suppressing G1Cyclin Expression

21 January 2018

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21 January 2018

Identifiers

DOI

10.4161/CC.20003

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11 September 2017

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