(Q39401953)

English

Hyper-activation of WNT/β-catenin signaling pathway mediates anti-tumor effects of histone deacetylase inhibitors in acute T lymphoblastic leukemia

scientific article published on 13 March 2012

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Europe PubMed Central

PubMed publication ID

11 September 2017

Hyper-activation of WNT/β-catenin signaling pathway mediates anti-tumor effects of histone deacetylase inhibitors in acute T lymphoblastic leukemia (English)

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Europe PubMed Central

PubMed publication ID

11 September 2017

author name string

Na Shao

1

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Europe PubMed Central

PubMed publication ID

11 September 2017

Jie Zou

2

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Europe PubMed Central

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11 September 2017

Jie Li

3

1 reference

Europe PubMed Central

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11 September 2017

Feng Chen

4

1 reference

Europe PubMed Central

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11 September 2017

Jianjian Dai

5

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Europe PubMed Central

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11 September 2017

Xun Qu

6

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Europe PubMed Central

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11 September 2017

Xiulian Sun

7

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Europe PubMed Central

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11 September 2017

Daoxin Ma

8

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Europe PubMed Central

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11 September 2017

Chunyan Ji

9

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11 September 2017

publication date

13 March 2012

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11 September 2017

Leukemia & Lymphoma

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11 September 2017

53

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Europe PubMed Central

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11 September 2017

9

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Europe PubMed Central

PubMed publication ID

11 September 2017

1769-1778

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Europe PubMed Central

PubMed publication ID

11 September 2017

Cytogenetics and molecular genetics of T-cell acute lymphoblastic leukemia: from thymocyte to lymphoblast

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2012.663085

21 January 2018

Histone deacetylases and cancer: causes and therapies

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2012.663085

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HATs and HDACs: from structure, function and regulation to novel strategies for therapy and prevention

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2012.663085

21 January 2018

Acetylation and deacetylation of non-histone proteins

1 reference

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21 January 2018

Histone deacetylase inhibitors in cancer therapy

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Mammalian sirtuins: biological insights and disease relevance

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Inhibitors of histone deacetylase as new anticancer agents

1 reference

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Histone deacetylase inhibitors: from target to clinical trials

1 reference

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21 January 2018

Histone deacetylase inhibitors as a new weapon in the arsenal of differentiation therapies of cancer

1 reference

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Clinical studies of histone deacetylase inhibitors.

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2012.663085

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The novel histone deacetylase inhibitor, LBH589, induces expression of DNA damage response genes and apoptosis in Ph- acute lymphoblastic leukemia cells

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2012.663085

21 January 2018

Histone deacetylase inhibitors synergistically potentiate death receptor 4-mediated apoptotic cell death of human T-cell acute lymphoblastic leukemia cells

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2012.663085

21 January 2018

Tubacin suppresses proliferation and induces apoptosis of acute lymphoblastic leukemia cells.

1 reference

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21 January 2018

Multiple Wnt signaling pathways converge to orient the mitotic spindle in early C. elegans embryos

1 reference

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21 January 2018

Regulation of hematopoiesis and the hematopoietic stem cell niche by Wnt signaling pathways

1 reference

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21 January 2018

WNT signalling and haematopoiesis: a WNT-WNT situation

1 reference

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21 January 2018

Epigenetic disruption of the WNT/beta-catenin signaling pathway in human cancers.

1 reference

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21 January 2018

LDL-receptor-related proteins in Wnt signal transduction

1 reference

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An LDL-receptor-related protein mediates Wnt signalling in mice

1 reference

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21 January 2018

arrow encodes an LDL-receptor-related protein essential for Wingless signalling

1 reference

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21 January 2018

Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2012.663085

21 January 2018

Oncogenic function of ATDC in pancreatic cancer through Wnt pathway activation and beta-catenin stabilization

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2012.663085

21 January 2018

Aberrant Wnt/beta-catenin signaling in pancreatic adenocarcinoma

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2012.663085

21 January 2018

The activation of beta-catenin by Wnt signaling mediates the effects of histone deacetylase inhibitors

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2012.663085

21 January 2018

Linear relationship between Wnt activity levels and apoptosis in colorectal carcinoma cells exposed to butyrate

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2012.663085

21 January 2018

Histone deacetylase inhibitor, suberoylanilide hydroxamic acid (Vorinostat, SAHA) profoundly inhibits the growth of human pancreatic cancer cells

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2012.663085

21 January 2018

Regulation of leukemic cell adhesion, proliferation, and survival by beta-catenin.

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2012.663085

21 January 2018

Variation in WNT genes expression in different subtypes of chronic lymphocytic leukemia

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2012.663085

21 January 2018

Acute myeloid leukemia is characterized by Wnt pathway inhibitor promoter hypermethylation

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2012.663085

21 January 2018

Modification of MTT assay conditions to examine the cytotoxic effects of amitraz on the human lymphoblastoid cell line, WIL2NS.

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2012.663085

21 January 2018

Wnt/beta-catenin signaling regulates cancer stem cells in lung cancer A549 cells

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2012.663085

21 January 2018

Histone deacetylase inhibitors: overview and perspectives

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2012.663085

21 January 2018

HDACi--targets beyond chromatin.

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2012.663085

21 January 2018

Wnt signaling pathway is epigenetically regulated by methylation of Wnt antagonists in acute myeloid leukemia.

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2012.663085

21 January 2018

WNT signaling controls expression of pro-apoptotic BOK and BAX in intestinal cancer

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2012.663085

21 January 2018

Regulation of armadillo by a Drosophila APC inhibits neuronal apoptosis during retinal development

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2012.663085

21 January 2018

Overexpression of beta-catenin induces apoptosis independent of its transactivation function with LEF-1 or the involvement of major G1 cell cycle regulators

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2012.663085

21 January 2018

The 'just-right' signaling model: APC somatic mutations are selected based on a specific level of activation of the beta-catenin signaling cascade.

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2012.663085

21 January 2018

APC dosage effects in tumorigenesis and stem cell differentiation

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2012.663085

21 January 2018

Apoptosis in neural crest cells by functional loss of APC tumor suppressor gene

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2012.663085

21 January 2018

Selection of multipotent stem cells during morphogenesis of small intestinal crypts of Lieberkuhn is perturbed by stimulation of Lef-1/beta-catenin signaling

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2012.663085

21 January 2018

Beta-catenin regulation during the cell cycle: implications in G2/M and apoptosis

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2012.663085

21 January 2018

Effects of p21(Cip1/Waf1) at both the G1/S and the G2/M cell cycle transitions: pRb is a critical determinant in blocking DNA replication and in preventing endoreduplication

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2012.663085

21 January 2018

HDAC inhibition decreases the expression of EGFR in colorectal cancer cells

1 reference

https://api.crossref.org/works/10.3109%2F10428194.2012.663085

21 January 2018

Histone deacetylase inhibitors prevent apoptosis following lethal hemorrhagic shock in rodent kidney cells

1 reference

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21 January 2018

Molecular determinants of the antitumor effects of trichostatin A in pancreatic cancer cells

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Wnt/β-catenin signaling regulates MAPK and Akt1 expression and growth of hepatocellular carcinoma cells.

1 reference

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21 January 2018

β-Catenin mediates cyclic strain-stimulated cardiomyogenesis in mouse embryonic stem cells through ROS-dependent and integrin-mediated PI3K/Akt pathways

1 reference

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21 January 2018

WNT unrelated activities in commercially available preparations of recombinant WNT3a.

1 reference

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21 January 2018

Identifiers

10.3109/10428194.2012.663085

1 reference

Europe PubMed Central

PubMed publication ID

11 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

11 September 2017

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