(Q39439223)

12 September 2017

title

The unfolded protein response controls induction and activation of ADAM17/TACE by severe hypoxia and ER stress (English)

1 reference

12 September 2017

0 references

6

1 reference

12 September 2017

T Rzymski

1

1 reference

12 September 2017

A Petry

2

1 reference

12 September 2017

D Kračun

3

1 reference

12 September 2017

F Rieß

4

1 reference

12 September 2017

L Pike

5

1 reference

12 September 2017

A Görlach

7

1 reference

12 September 2017

language of work or name

English

0 references

publication date

21 November 2011

1 reference

12 September 2017

1 reference

12 September 2017

volume

31

1 reference

12 September 2017

issue

31

1 reference

12 September 2017

page(s)

3621-3634

1 reference

Signalling pathways of the TNF superfamily: a double-edged sword

12 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.522

TNF-alpha converting enzyme (TACE) is inhibited by TIMP-3

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.522

Hypoxia enhances cancer cell invasion through relocalization of the proprotein convertase furin from the trans-Golgi network to the cell surface

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.522

Tumour necrosis factor and cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.522

ER stress-regulated translation increases tolerance to extreme hypoxia and promotes tumor growth

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.522

A metalloproteinase disintegrin that releases tumour-necrosis factor-alpha from cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.522

Perk-dependent translational regulation promotes tumor cell adaptation and angiogenesis in response to hypoxic stress

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.522

Up-regulated expression of ADAM17 in human colon carcinoma: co-expression with EGFR in neoplastic and endothelial cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.522

A selective inhibitor of eIF2alpha dephosphorylation protects cells from ER stress

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.522

Exploiting tumour hypoxia in cancer treatment

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.522

Targeting TNF-alpha for cancer therapy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.522

Hypoxia-inducible factor mediates hypoxic and tumor necrosis factor alpha-induced increases in tumor necrosis factor-alpha converting enzyme/ADAM17 expression by synovial cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.522

Identification of mitogen-activated protein kinase signaling pathways that confer resistance to endoplasmic reticulum stress in Saccharomyces cerevisiae

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.522

Oxygen sensing and hypoxia-induced responses

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.522

PERK-dependent activation of Nrf2 contributes to redox homeostasis and cell survival following endoplasmic reticulum stress

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.522

Extracellular signal-regulated kinase phosphorylates tumor necrosis factor alpha-converting enzyme at threonine 735: a potential role in regulated shedding.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.522

The NADPH oxidase subunit NOX4 is a new target gene of the hypoxia-inducible factor-1.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.522

Soluble receptors for tumour necrosis factor in clinical laboratory diagnosis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.522

Current uses of isolated limb perfusion in the clinic and a model system for new strategies

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.522

A phase I trial of intravenously-administered recombinant tumor necrosis factor-alpha in cancer patients

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.522

Hypoxia, inflammation, and the tumor microenvironment in metastatic disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.522

Treatment of patients with melanoma of the extremity using hyperthermic isolated limb perfusion with melphalan, tumor necrosis factor, and interferon gamma: results of a tumor necrosis factor dose-escalation study

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.522

The unfolded protein response is an important regulator of inflammatory genes in endothelial cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.522

The endoplasmic reticulum: folding, calcium homeostasis, signaling, and redox control

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.522

Immunity, Inflammation, and Cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.522

An integrated stress response regulates amino acid metabolism and resistance to oxidative stress

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.522

Hypoxia--a key regulatory factor in tumour growth

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.522

Complementary DNA cloning of a receptor for tumor necrosis factor and demonstration of a shed form of the receptor

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.522

Critical role of endogenous Akt/IAPs and MEK1/ERK pathways in counteracting endoplasmic reticulum stress-induced cell death

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.522

Autocrine tumor necrosis factor alpha links endoplasmic reticulum stress to the membrane death receptor pathway through IRE1alpha-mediated NF-kappaB activation and down-regulation of TRAF2 expression

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.522

Endoplasmic reticulum stress stimulates the expression of cyclooxygenase-2 through activation of NF-kappaB and pp38 mitogen-activated protein kinase

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.522

Inhibition of MEK sensitizes human melanoma cells to endoplasmic reticulum stress-induced apoptosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.522

NF-kappaB: linking inflammation and immunity to cancer development and progression

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.522

Targeting TACE-dependent EGFR ligand shedding in breast cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.522

Overexpression of TACE and TIMP3 mRNA in head and neck cancer: association with tumour development and progression.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.522

Regulation of protein synthesis by hypoxia via activation of the endoplasmic reticulum kinase PERK and phosphorylation of the translation initiation factor eIF2alpha

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.522

"Translating" tumor hypoxia: unfolded protein response (UPR)-dependent and UPR-independent pathways

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.522

31 March 2020

NSAIDs and gut toxicity

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.522

Endoplasmic reticulum stress is implicated in retinal inflammation and diabetic retinopathy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.522

Hypoxic reactive oxygen species regulate the integrated stress response and cell survival.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.522

Molecular cloning and expression of the human 55 kd tumor necrosis factor receptor

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.522

Cytoprotection by pre-emptive conditional phosphorylation of translation initiation factor 2

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.522

Cancer-related inflammation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.522

The expression of the ADAMs proteases in prostate cancer cell lines and their regulation by dihydrotestosterone

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.522

ADAM-17 expression in breast cancer correlates with variables of tumor progression.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.522

Hypoxia-enhanced expression of the proprotein convertase furin is mediated by hypoxia-inducible factor-1: impact on the bioactivation of proproteins.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.522

Specific sequence elements are required for the expression of functional tumor necrosis factor-alpha-converting enzyme (TACE).

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.522

ADAMs in cancer cell proliferation and progression.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.522

Hypoxic activation of the unfolded protein response (UPR) induces expression of the metastasis-associated gene LAMP3.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.522

The ADAMs: signalling scissors in the tumour microenvironment

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.522

Mitochondrial reactive oxygen species mediate GPCR-induced TACE/ADAM17-dependent transforming growth factor-alpha shedding

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.522

Up-regulated expression of ADAM17 in gastrointestinal stromal tumors: coexpression with EGFR and EGFR ligands.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.522

Soluble forms of tumor necrosis factor receptors (TNF-Rs). The cDNA for the type I TNF-R, cloned using amino acid sequence data of its soluble form, encodes both the cell surface and a soluble form of the receptor

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.522

Furin-dependent intracellular activation of the human stromelysin-3 zymogen

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.522

Endoplasmic reticulum calcium depletion impacts chaperone secretion, innate immunity, and phagocytic uptake of cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.522

Soluble tumour necrosis factor receptors as prognostic factors in cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.522

XBP1 is essential for survival under hypoxic conditions and is required for tumor growth.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.522

Signal integration in the endoplasmic reticulum unfolded protein response

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.522

The unfolded protein response and integrated stress response to anoxia

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.522

Regulation of autophagy by ATF4 in response to severe hypoxia.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.522

Multiple pathways are involved in the anoxia response of SKIP3 including HuR-regulated RNA stability, NF-kappaB and ATF4.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.522

Molecular cloning and expression of a receptor for human tumor necrosis factor

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.522

The ADAMs family of metalloproteases: multidomain proteins with multiple functions

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.522

Targeting HIF-1 for cancer therapy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.522

TACE/ADAM-17 maturation and activation of sheddase activity require proprotein convertase activity.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.522

Transcription factor Sp1 induces ADAM17 and contributes to tumor cell invasiveness under hypoxia

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.522

Tumour necrosis factor alpha: a potential target for the therapy of solid tumours.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.522

Clinical significance of heparin-binding epidermal growth factor-like growth factor and a disintegrin and metalloprotease 17 expression in human ovarian cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.522

TNF-alpha-converting enzyme (TACE/ADAM17)-dependent loss of CD30 induced by proteasome inhibition through reactive oxygen species

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.522

Tumor necrosis factor soluble receptors circulate during experimental and clinical inflammation and can protect against excessive tumor necrosis factor alpha in vitro and in vivo

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.522

Tumour necrosis factor (TNF) soluble receptors in malignant melanoma: correlation with soluble ICAM-1 levels

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.522

Soluble tumor necrosis factor (TNF) receptor-1 induces apoptosis via reverse TNF signaling and autocrine transforming growth factor-beta1.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.522

Thiol isomerases negatively regulate the cellular shedding activity of ADAM17.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.522

Direct activation of TACE-mediated ectodomain shedding by p38 MAP kinase regulates EGF receptor-dependent cell proliferation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.522

Tumor necrosis factor alpha (TNFalpha) induces the unfolded protein response (UPR) in a reactive oxygen species (ROS)-dependent fashion, and the UPR counteracts ROS accumulation by TNFalpha

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.522

ADAMs (a disintegrin and metalloproteinase) messenger RNA expression in Helicobacter pylori-infected, normal, and neoplastic gastric mucosa

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.522

From endoplasmic-reticulum stress to the inflammatory response

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.522

Reactive oxygen species mediate tumor necrosis factor alpha-converting, enzyme-dependent ectodomain shedding induced by phorbol myristate acetate

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.522

ADAM17 promotes breast cancer cell malignant phenotype through EGFR-PI3K-AKT activation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.522

31 March 2020

Identifiers

DOI

10.1038/ONC.2011.522

1 reference

Dimensions Publication ID

12 September 2017

1025923118

0 references

1 reference