(Q39447177)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23518712%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

title

Modulation of dendritic cell properties by laquinimod as a mechanism for modulating multiple sclerosis (English)

1 reference

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26 February 2020

0 references

1 reference

11

1 reference

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26 February 2020

Helmut Jonuleit

13

1 reference

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26 February 2020

Frauke Zipp

14

1 reference

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26 February 2020

Valérie Jolivel

1

1 reference

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26 February 2020

Volker Siffrin

12

1 reference

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26 February 2020

Ari Waisman

15

1 reference

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26 February 2020

2

Felix Luessi

1 reference

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26 February 2020

8

Magdalena Paterka

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23518712%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

6

Laura Poisa-Beiro

1 reference

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26 February 2020

9

Nir Yogev

1 reference

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26 February 2020

10

Hayrettin Tumani

1 reference

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26 February 2020

author name string

Joumana Masri

3

1 reference

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26 February 2020

Stefan H P Kraus

4

1 reference

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26 February 2020

Mario Hubo

5

1 reference

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26 February 2020

Sabrina Klebow

7

1 reference

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26 February 2020

language of work or name

English

0 references

publication date

20 March 2013

1 reference

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26 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23518712%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

volume

136

1 reference

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26 February 2020

issue

Pt 4

1 reference

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26 February 2020

page(s)

1048-1066

1 reference

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Interleukins 1beta and 6 but not transforming growth factor-beta are essential for the differentiation of interleukin 17-producing human T helper cells

26 February 2020

cites work

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT023

Infiltrating monocytes trigger EAE progression, but do not contribute to the resident microglia pool.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT023

Reduced astrocytic NF-κB activation by laquinimod protects from cuprizone-induced demyelination

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT023

The new orally active immunoregulator laquinimod (ABR-215062) effectively inhibits development and relapses of experimental autoimmune encephalomyelitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT023

Inflammation triggers synaptic alteration and degeneration in experimental autoimmune encephalomyelitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT023

Critical regulation of early Th17 cell differentiation by interleukin-1 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT023

Placebo-controlled trial of oral laquinimod for multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT023

Effect of laquinimod on MRI-monitored disease activity in patients with relapsing-remitting multiple sclerosis: a multicentre, randomised, double-blind, placebo-controlled phase IIb study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT023

Interleukin-1 in the pathogenesis and treatment of inflammatory diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT023

Fumarates improve psoriasis and multiple sclerosis by inducing type II dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT023

Expression of chemokines RANTES, MIP-1alpha and GRO-alpha correlates with inflammation in acute experimental autoimmune encephalomyelitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT023

The immunological synapse: a molecular machine controlling T cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT023

Coexpression of NF-kappa B/Rel and Sp1 transcription factors in human immunodeficiency virus 1-induced, dendritic cell-T-cell syncytia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT023

Dendritic cells permit immune invasion of the CNS in an animal model of multiple sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT023

Laquinimod suppress antigen presentation in relapsing-remitting multiple sclerosis: in-vitro high-throughput gene expression study

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT023

IL-1β and TGF-β act antagonistically in induction and differentially in propagation of human proinflammatory precursor CD4+ T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT023

Differential activation of NF-kappa B subunits in dendritic cells in response to Gram-negative bacteria and to lipopolysaccharide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT023

Increased expression of ICAM-1, VCAM-1, MCP-1, and MIP-1 alpha by spinal perivascular macrophages during experimental allergic encephalomyelitis in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT023

Synthesis and biological evaluation of new 1,2-dihydro-4-hydroxy-2-oxo-3-quinolinecarboxamides for treatment of autoimmune disorders: structure-activity relationship

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT023

Induction of interleukin 10-producing, nonproliferating CD4(+) T cells with regulatory properties by repetitive stimulation with allogeneic immature human dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT023

Lipid microarrays identify key mediators of autoimmune brain inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT023

Changes in circulating dendritic cells and B-cells in patients with multiple sclerosis relapse during corticosteroid therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT023

B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: application to autoimmune disease therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT023

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT023

Crucial role of CCL3/MIP-1alpha in the recurrence of autoimmune anterior uveitis induced with myelin basic protein in Lewis rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT023

Chemokines and dendritic cells: a crucial alliance

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT023

MCP-1, MCP-2 and MCP-3 expression in multiple sclerosis lesions: an immunohistochemical and in situ hybridization study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT023

Human dendritic cell subsets from spleen and blood are similar in phenotype and function but modified by donor health status.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT023

Three-dimensional segregation of supramolecular activation clusters in T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT023

CD8alpha- CD11b+ dendritic cells present exogenous virus-like particles to CD8+ T cells and subsequently express CD8alpha and CD205 molecules.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT023

The immunomodulator FTY720 interferes with effector functions of human monocyte-derived dendritic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT023

Properties of the novel proinflammatory supergene "intercrine" cytokine family.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT023

Enumeration of human peripheral blood dendritic cells throughout the life

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT023

Estriol generates tolerogenic dendritic cells in vivo that protect against autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT023

Treatment with laquinimod reduces development of active MRI lesions in relapsing MS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT023

CD11c-expressing cells reside in the juxtavascular parenchyma and extend processes into the glia limitans of the mouse nervous system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT023

Dendritic cell survival and maturation are regulated by different signaling pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT023

Novel insights into the relationships between dendritic cell subsets in human and mouse revealed by genome-wide expression profiling

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT023

Abnormal activity of the Na/Ca exchanger enhances glutamate transmission in experimental autoimmune encephalomyelitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT023

Inhibition of the development of chronic experimental autoimmune encephalomyelitis by laquinimod (ABR-215062) in IFN-beta k.o. and wild type mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT023

Distinct patterns and kinetics of chemokine production regulate dendritic cell function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT023

Interleukin-10 production by Th1 cells requires interleukin-12-induced STAT4 transcription factor and ERK MAP kinase activation by high antigen dose

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT023

Laquinimod, a quinoline-3-carboxamide, induces type II myeloid cells that modulate central nervous system autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT023

Treatment of multiple sclerosis with the pregnancy hormone estriol

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT023

Differential immune cell dynamics in the CNS cause CD4+ T cell compartmentalization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT023

Expression of monocyte chemoattractant protein-1 and other beta-chemokines by resident glia and inflammatory cells in multiple sclerosis lesions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT023

Signal transduction inhibition of APCs diminishes th17 and Th1 responses in experimental autoimmune encephalomyelitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT023

The role of group 1 and group 2 CD1-restricted T cells in microbial immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT023

Selective depletion of splenic CD4 dendritic cells in mice treated with immunomodulatory quinoline-3-carboxamide ABR-215757.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT023

Modulation of autoimmune demyelination by laquinimod via induction of brain-derived neurotrophic factor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT023

Alternate splicing of interleukin-1 receptor type II (IL1R2) in vitro correlates with clinical glucocorticoid responsiveness in patients with AIED.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT023

Type II monocytes modulate T cell-mediated central nervous system autoimmune disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT023

Multiple sclerosis: glatiramer acetate inhibits monocyte reactivity in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT023

Laquinimod interferes with migratory capacity of T cells and reduces IL-17 levels, inflammatory demyelination and acute axonal damage in mice with experimental autoimmune encephalomyelitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT023

A role for interleukin-2 trans-presentation in dendritic cell-mediated T cell activation in humans, as revealed by daclizumab therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT023

Laquinimod (ABR-215062) suppresses the development of experimental autoimmune encephalomyelitis, modulates the Th1/Th2 balance and induces the Th3 cytokine TGF-beta in Lewis rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT023

Suppression of experimental autoimmune neuritis by ABR-215062 is associated with altered Th1/Th2 balance and inhibited migration of inflammatory cells into the peripheral nerve tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT023

Demonstration of the Th1 to Th2 cytokine shift during the course of HIV-1 infection using cytoplasmic cytokine detection on single cell level by flow cytometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWT023

21 January 2018

Identifiers

DOI

10.1093/BRAIN/AWT023

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23518712%20AND%20SRC:MED&resulttype=core&format=json

26 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23518712%20AND%20SRC:MED&resulttype=core&format=json