(Q35441339)

8 August 2017

title

Fumarates improve psoriasis and multiple sclerosis by inducing type II dendritic cells (English)

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8 August 2017

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Robert Feil

14

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author name string

Kamran Ghoreschi

1

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8 August 2017

Jürgen Brück

2

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8 August 2017

Christina Kellerer

3

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8 August 2017

Caishu Deng

4

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8 August 2017

Haiyan Peng

5

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8 August 2017

Oliver Rothfuss

6

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8 August 2017

Rehana Z Hussain

7

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8 August 2017

Anne R Gocke

8

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8 August 2017

Annedore Respa

9

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8 August 2017

Ivana Glocova

10

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8 August 2017

Nadejda Valtcheva

11

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8 August 2017

Eva Alexander

12

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8 August 2017

Susanne Feil

13

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8 August 2017

Klaus Schulze-Osthoff

15

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8 August 2017

Rudolf A Rupec

16

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8 August 2017

Amy E Lovett-Racke

17

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8 August 2017

Ralf Dringen

18

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8 August 2017

Michael K Racke

19

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8 August 2017

Martin Röcken

20

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8 August 2017

language of work or name

English

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publication date

10 October 2011

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Journal of Experimental Medicine

8 August 2017

published in

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8 August 2017

volume

208

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8 August 2017

issue

11

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8 August 2017

page(s)

2291-2303

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Fumaric acid esters exert neuroprotective effects in neuroinflammation via activation of the Nrf2 antioxidant pathway.

8 August 2017

cites work

1 reference

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T helper type 1 and 17 cells determine efficacy of interferon-beta in multiple sclerosis and experimental encephalomyelitis

12 July 2018

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Parkin protects mitochondrial genome integrity and supports mitochondrial DNA repair

12 July 2018

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AP-1 activated by toll-like receptors regulates expression of IL-23 p19.

12 July 2018

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Direct crosstalk between mast cell-TNF and TNFR1-expressing endothelia mediates local tissue inflammation

12 July 2018

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Myeloid heme oxygenase-1 regulates innate immunity and autoimmunity by modulating IFN-beta production.

12 July 2018

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12 July 2018

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Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways

12 July 2018

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Repeated subcutaneous injections of IL12/23 p40 neutralising antibody, ustekinumab, in patients with relapsing-remitting multiple sclerosis: a phase II, double-blind, placebo-controlled, randomised, dose-ranging study

12 July 2018

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Ethyl pyruvate has an anti-inflammatory effect by inhibiting ROS-dependent STAT signaling in activated microglia

12 July 2018

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A proximal kappaB site in the IL-23 p19 promoter is responsible for RelA- and c-Rel-dependent transcription

12 July 2018

1 reference

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Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants

12 July 2018

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Heme oxygenase-1 protein localizes to the nucleus and activates transcription factors important in oxidative stress

12 July 2018

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A human interleukin-12/23 monoclonal antibody for the treatment of psoriasis

12 July 2018

1 reference

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Heme oxygenase-1 and carbon monoxide suppress autoimmune neuroinflammation

12 July 2018

1 reference

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Differential antigen processing by dendritic cell subsets in vivo

12 July 2018

1 reference

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Carbon monoxide differentially inhibits TLR signaling pathways by regulating ROS-induced trafficking of TLRs to lipid rafts

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201195

Multiple sclerosis--the plaque and its pathogenesis

12 July 2018

1 reference

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A randomized, placebo-controlled trial of natalizumab for relapsing multiple sclerosis

12 July 2018

1 reference

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Carbon monoxide ameliorates chronic murine colitis through a heme oxygenase 1-dependent pathway

12 July 2018

1 reference

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Selected Toll-like receptor agonist combinations synergistically trigger a T helper type 1-polarizing program in dendritic cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201195

A type I interferon autocrine-paracrine loop is involved in Toll-like receptor-induced interleukin-12p70 secretion by dendritic cells.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201195

Dimethylfumarate for psoriasis: more than a dietary curiosity

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201195

Synergistic activation of interleukin-12 p35 gene transcription by interferon regulatory factor-1 and interferon consensus sequence-binding protein

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201195

Loss of T-bet, but not STAT1, prevents the development of experimental autoimmune encephalomyelitis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201195

Controlling the Toll road to dendritic cell polarization

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201195

Dendritic-cell control of pathogen-driven T-cell polarization

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201195

A molecule solves psoriasis? Systemic therapies for psoriasis inducing interleukin 4 and Th2 responses

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201195

The use of dendritic cells in cancer immunotherapy

12 July 2018

1 reference

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Interleukin-4 therapy of psoriasis induces Th2 responses and improves human autoimmune disease

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201195

Experimental autoimmune encephalitis and inflammation in the absence of interleukin-12

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201195

Repetitive injections of dendritic cells matured with tumor necrosis factor alpha induce antigen-specific protection of mice from autoimmunity.

12 July 2018

1 reference

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An advanced culture method for generating large quantities of highly pure dendritic cells from mouse bone marrow

12 July 2018

1 reference

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Glutathione levels in antigen-presenting cells modulate Th1 versus Th2 response patterns

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201195

Glutathione content as an indicator for the presence of metabolic pathways of amino acids in astroglial cultures.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201195

Selective stimulation of T helper 2 cytokine responses by the anti-psoriasis agent monomethylfumarate

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201195

Cytokine-induced immune deviation as a therapy for inflammatory autoimmune disease

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201195

Thiols decrease human interleukin (IL) 4 production and IL-4-induced immunoglobulin synthesis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201195

Heme oxygenase is the major 32-kDa stress protein induced in human skin fibroblasts by UVA radiation, hydrogen peroxide, and sodium arsenite

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201195

Targeting glutathione by dimethylfumarate protects against experimental malaria by enhancing erythrocyte cell membrane scrambling.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201195

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201195

Efficacy and safety of oral fumarate in patients with relapsing-remitting multiple sclerosis: a multicentre, randomised, double-blind, placebo-controlled phase IIb study

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201195

Type II monocytes modulate T cell-mediated central nervous system autoimmune disease

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201195

Dimethylfumarate induces immunosuppression via glutathione depletion and subsequent induction of heme oxygenase 1.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201195

Electrophilic chemicals but not UV irradiation or reactive oxygen species activate Nrf2 in keratinocytes in vitro and in vivo.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201195

Monomethylfumarate affects polarization of monocyte-derived dendritic cells resulting in down-regulated Th1 lymphocyte responses.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201195

Effect of glutathione-S-transferase M1 and P1 genotypes on xenobiotic enhancement of allergic responses: randomised, placebo-controlled crossover study

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201195

Beneficial effects of fumarate therapy in psoriasis vulgaris patients coincide with downregulation of type 1 cytokines

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201195

Dimethylfumarate inhibits TNF-induced nuclear entry of NF-kappa B/p65 in human endothelial cells

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201195

Reversal of established delayed type hypersensitivity reactions following therapy with IL-4 or antigen-specific Th2 cells

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3201195

Fumaric acid esters are effective in chronic experimental autoimmune encephalomyelitis and suppress macrophage infiltration

26 September 2018

1 reference

12 December 2020

Essential roles of c-Rel in TLR-induced IL-23 p19 gene expression in dendritic cells

1 reference

12 December 2020

Fumarate esters as angiogenesis inhibitors: key to action in psoriasis?

1 reference

12 December 2020

IL-4 instructs TH1 responses and resistance to Leishmania major in susceptible BALB/c mice

1 reference

12 December 2020

Activation of the murine interleukin-12 p40 promoter by functional interactions between NFAT and ICSBP

1 reference

12 December 2020

Antipsoriatic effect of fumaric acid derivatives. Results of a multicenter double-blind study in 100 patients

1 reference

12 December 2020

Identifiers

DOI

10.1084/JEM.20100977

1 reference

release_p4gaamezjvfm7h7pgvx2l6vjlq

8 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/p4gaamezjvfm7h7pgvx2l6vjlq

24 November 2022

mapped directly with Wikidata item

PMC publication ID

3201195

1 reference

8 August 2017

1 reference