(Q39454084)

English

1-Benzyl-3-cetyl-2-methylimidazolium iodide (NH125) induces phosphorylation of eukaryotic elongation factor-2 (eEF2): a cautionary note on the anticancer mechanism of an eEF2 kinase inhibitor

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

1-Benzyl-3-cetyl-2-methylimidazolium iodide (NH125) induces phosphorylation of eukaryotic elongation factor-2 (eEF2): a cautionary note on the anticancer mechanism of an eEF2 kinase inhibitor (English)

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

phosphorylation

1 reference

based on heuristic

inferred from title

author name string

Zehan Chen

1

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

Sujatha M Gopalakrishnan

2

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

Mai-Ha Bui

3

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

Niru B Soni

4

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

Usha Warrior

5

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

Eric F Johnson

6

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

Jennifer B Donnelly

7

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

Keith B Glaser

8

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

language of work or name

0 references

publication date

21 October 2011

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

number of pages

8

1 reference

based on heuristic

inferred from page(s)

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

286

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

51

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

43951-43958

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

Immunoregulatory functions of mTOR inhibition.

1 reference

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12 September 2017

Ca2+ signalling checkpoints in cancer: remodelling Ca2+ for cancer cell proliferation and survival

1 reference

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12 September 2017

Selective Chk1 inhibitors differentially sensitize p53-deficient cancer cells to cancer therapeutics

1 reference

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12 September 2017

Elongation factor-2 kinase: its role in protein synthesis and autophagy

1 reference

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12 September 2017

Identification and characterization of a small molecule AMPK activator that treats key components of type 2 diabetes and the metabolic syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3243513

12 September 2017

Calcium/calmodulin-dependent protein kinases as potential targets in cancer therapy.

1 reference

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12 September 2017

AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3243513

12 September 2017

A novel mTOR-regulated phosphorylation site in elongation factor 2 kinase modulates the activity of the kinase and its binding to calmodulin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3243513

12 September 2017

Microarrayed compound screening (microARCS) to identify activators and inhibitors of AMP-activated protein kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3243513

12 September 2017

Identification of specific PP2A complexes involved in human cell transformation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3243513

12 September 2017

Stimulation of the AMP-activated protein kinase leads to activation of eukaryotic elongation factor 2 kinase and to its phosphorylation at a novel site, serine 398

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3243513

12 September 2017

Regulation of peptide-chain elongation in mammalian cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3243513

12 September 2017

Activation of AMP-activated protein kinase leads to the phosphorylation of elongation factor 2 and an inhibition of protein synthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3243513

12 September 2017

Elongation factor-2 kinase and its newly discovered relatives

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3243513

12 September 2017

Role of AMP-activated protein kinase in mechanism of metformin action

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3243513

12 September 2017

Mapping the functional domains of elongation factor-2 kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3243513

12 September 2017

Regulation of elongation factor-2 by multisite phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3243513

12 September 2017

Identification of the major Mr 100,000 substrate for calmodulin-dependent protein kinase III in mammalian cells as elongation factor-2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3243513

12 September 2017

Phosphorylation of elongation factor 2 by EF-2 kinase affects rate of translation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3243513

12 September 2017

Silencing of elongation factor-2 kinase potentiates the effect of 2-deoxy-D-glucose against human glioma cells through blunting of autophagy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3243513

14 September 2017

Alcohol regulates eukaryotic elongation factor 2 phosphorylation via an AMP-activated protein kinase-dependent mechanism in C2C12 skeletal myocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3243513

14 September 2017

Elongation factor-2 kinase regulates autophagy in human glioblastoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3243513

14 September 2017

The farnesyl transferase inhibitor (FTI) SCH66336 (lonafarnib) inhibits Rheb farnesylation and mTOR signaling. Role in FTI enhancement of taxane and tamoxifen anti-tumor activity

1 reference

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14 September 2017

P-glycoprotein mediates resistance to histidine kinase inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3243513

14 September 2017

Identification and characterization of an inhibitor of eukaryotic elongation factor 2 kinase against human cancer cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3243513

14 September 2017

Regulation of elongation factor-2 kinase by pH.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3243513

14 September 2017

Lopinavir impairs protein synthesis and induces eEF2 phosphorylation via the activation of AMP-activated protein kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3243513

17 June 2018

Novel compounds, '1,3-selenazine derivatives' as specific inhibitors of eukaryotic elongation factor-2 kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3243513

17 June 2018

Antibacterial agents that inhibit histidine protein kinase YycG of Bacillus subtilis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3243513

21 August 2018

Mechanism of elongation factor 2 (EF-2) inactivation upon phosphorylation. Phosphorylated EF-2 is unable to catalyze translocation

1 reference

https://pubmed.ncbi.nlm.nih.gov/22020937

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification and characterization of a potent antibacterial agent, NH125 against drug-resistant bacteria

1 reference

https://pubmed.ncbi.nlm.nih.gov/22020937

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M111.301291

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 September 2017

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