(Q39457360)

12 September 2017

title

The asparaginyl hydroxylase factor-inhibiting HIF is essential for tumor growth through suppression of the p53-p21 axis (English)

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12 September 2017

6

J Pouysségur

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Jerome Durivault

object named as

J Durivault

3

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author name string

J Pelletier

1

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12 September 2017

F Dayan

2

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12 September 2017

K Ilc

4

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12 September 2017

E Pécou

5

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12 September 2017

N M Mazure

7

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12 September 2017

language of work or name

English

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publication date

17 October 2011

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12 September 2017

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12 September 2017

volume

31

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12 September 2017

issue

24

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12 September 2017

page(s)

2989-3001

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HIF prolyl-hydroxylase 2 is the key oxygen sensor setting low steady-state levels of HIF-1alpha in normoxia

12 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.471

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.471

Hypoxia-inducible carbonic anhydrase IX and XII promote tumor cell growth by counteracting acidosis through the regulation of the intracellular pH.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.471

Posttranslational hydroxylation of ankyrin repeats in IkappaB proteins by the hypoxia-inducible factor (HIF) asparaginyl hydroxylase, factor inhibiting HIF (FIH)

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.471

FIH-dependent asparaginyl hydroxylation of ankyrin repeat domain-containing proteins.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.471

A dialogue between the hypoxia-inducible factor and the tumor microenvironment

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.471

Gene regulation in response to graded hypoxia: the non-redundant roles of the oxygen sensors PHD and FIH in the HIF pathway

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.471

The oxygen sensor factor-inhibiting hypoxia-inducible factor-1 controls expression of distinct genes through the bifunctional transcriptional character of hypoxia-inducible factor-1alpha

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.471

A novel bHLH-PAS factor with close sequence similarity to hypoxia-inducible factor 1alpha regulates the VEGF expression and is potentially involved in lung and vascular development

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.471

HIF-1alpha and p53: the ODD couple?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.471

HRF, a putative basic helix-loop-helix-PAS-domain transcription factor is closely related to hypoxia-inducible factor-1 alpha and developmentally expressed in blood vessels

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.471

Characterization of a subset of the basic-helix-loop-helix-PAS superfamily that interacts with components of the dioxin signaling pathway

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.471

The N-terminal transactivation domain confers target gene specificity of hypoxia-inducible factors HIF-1alpha and HIF-2alpha

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.471

Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.471

Comment on the role of FIH in the inhibitory effect of bortezomib on hypoxia-inducible factor-1.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.471

Catalytic properties of the asparaginyl hydroxylase (FIH) in the oxygen sensing pathway are distinct from those of its prolyl 4-hydroxylases

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.471

Expression of nuclear FIH independently predicts overall survival of clear cell renal cell carcinoma patients

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.471

FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.471

Asparagine hydroxylation of the HIF transactivation domain a hypoxic switch

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.471

Substrate requirements of the oxygen-sensing asparaginyl hydroxylase factor-inhibiting hypoxia-inducible factor

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.471

miR-31 ablates expression of the HIF regulatory factor FIH to activate the HIF pathway in head and neck carcinoma.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.471

Turn me on: regulating HIF transcriptional activity.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.471

FIH-1: a novel protein that interacts with HIF-1alpha and VHL to mediate repression of HIF-1 transcriptional activity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.471

Transcriptional regulation of vascular endothelial cell responses to hypoxia by HIF-1.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.471

Molecular genetic analysis of FIH-1, FH, and SDHB candidate tumour suppressor genes in renal cell carcinoma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.471

The significance of telomerase activation and cellular immortalization in human cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.471

Oxygen-regulated and transactivating domains in endothelial PAS protein 1: comparison with hypoxia-inducible factor-1alpha.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.471

Hypoxia signalling in cancer and approaches to enforce tumour regression

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.471

Mint3 enhances the activity of hypoxia-inducible factor-1 (HIF-1) in macrophages by suppressing the activity of factor inhibiting HIF-1

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.471

Factor inhibiting HIF limits the expression of hypoxia-inducible genes in podocytes and distal tubular cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.471

HIF-1: upstream and downstream of cancer metabolism

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.471

Bortezomib inhibits tumor adaptation to hypoxia by stimulating the FIH-mediated repression of hypoxia-inducible factor-1.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.471

Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.471

Differential sensitivity of hypoxia inducible factor hydroxylation sites to hypoxia and hydroxylase inhibitors

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.471

Specific inhibition of gene expression using a stably integrated, inducible small-interfering-RNA vector

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.471

Blinded by the Light: The Growing Complexity of p53

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.471

Conditional suppression of cellular genes: lentivirus vector-mediated drug-inducible RNA interference

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.471

BLIMP1 regulates cell growth through repression of p53 transcription.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.471

The asparaginyl hydroxylase factor inhibiting HIF-1alpha is an essential regulator of metabolism

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2011.471

31 March 2020

Identifiers

DOI

10.1038/ONC.2011.471

1 reference

12 September 2017

1 reference