(Q39467227)

12 September 2017

Copper inducing Aβ42 rather than Aβ40 nanoscale oligomer formation is the key process for Aβ neurotoxicity (English)

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12 September 2017

1 reference

Lu Jin

1

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12 September 2017

Wei-Hui Wu

2

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12 September 2017

Qiu-Ye Li

3

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12 September 2017

Yu-Fen Zhao

4

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12 September 2017

Yan-Mei Li

5

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12 September 2017

language of work or name

English

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publication date

26 September 2011

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12 September 2017

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12 September 2017

3

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12 September 2017

11

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12 September 2017

4746-4751

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Amyloid plaque core protein in Alzheimer disease and Down syndrome

12 September 2017

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https://api.crossref.org/works/10.1039%2FC1NR11029B

beta-Amyloid-(1-42) is a major component of cerebrovascular amyloid deposits: implications for the pathology of Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NR11029B

Amyloid beta-protein assembly and Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NR11029B

A specific amyloid-beta protein assembly in the brain impairs memory

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NR11029B

An increased percentage of long amyloid beta protein secreted by familial amyloid beta protein precursor (beta APP717) mutants.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NR11029B

Pathogenic APP mutations near the gamma-secretase cleavage site differentially affect Abeta secretion and APP C-terminal fragment stability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NR11029B

The carboxy terminus of the beta amyloid protein is critical for the seeding of amyloid formation: implications for the pathogenesis of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NR11029B

Amyloid beta -protein (Abeta) assembly: Abeta 40 and Abeta 42 oligomerize through distinct pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NR11029B

Metals and amyloid-beta in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NR11029B

Copper-mediated amyloid-beta toxicity is associated with an intermolecular histidine bridge.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NR11029B

Dramatic aggregation of Alzheimer abeta by Cu(II) is induced by conditions representing physiological acidosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NR11029B

Cu(2+) Inhibits the Aggregation of Amyloid beta-Peptide(1-42) in vitro We thank JEOL for the AFM measurement. This work was supported in part by Grants-in-Aid from the Japanese Ministry of Education, Science, Sports, and Culture, and a Grant from "R

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NR11029B

Copper, iron and zinc in Alzheimer's disease senile plaques.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NR11029B

The metallobiology of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NR11029B

Sequestration of copper from beta-amyloid promotes selective lysis by cyclen-hybrid cleavage agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NR11029B

Rapid restoration of cognition in Alzheimer's transgenic mice with 8-hydroxy quinoline analogs is associated with decreased interstitial Abeta

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NR11029B

Concentration dependent Cu2+ induced aggregation and dityrosine formation of the Alzheimer's disease amyloid-beta peptide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NR11029B

Copper enhances amyloid-beta peptide neurotoxicity and non beta-aggregation: a series of experiments conducted upon copper-bound and copper-free amyloid-beta peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NR11029B

New insights on how metals disrupt amyloid beta-aggregation and their effects on amyloid-beta cytotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NR11029B

Substoichiometric levels of Cu2+ ions accelerate the kinetics of fiber formation and promote cell toxicity of amyloid-{beta} from Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NR11029B

Cu(II) potentiation of alzheimer abeta neurotoxicity. Correlation with cell-free hydrogen peroxide production and metal reduction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NR11029B

Metalloenzyme-like activity of Alzheimer's disease beta-amyloid. Cu-dependent catalytic conversion of dopamine, cholesterol, and biological reducing agents to neurotoxic H(2)O(2).

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NR11029B

Metal swap between Zn7-metallothionein-3 and amyloid-beta-Cu protects against amyloid-beta toxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NR11029B

Cu(II) binding to monomeric, oligomeric, and fibrillar forms of the Alzheimer's disease amyloid-beta peptide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NR11029B

Oligomeric and fibrillar species of amyloid-beta peptides differentially affect neuronal viability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NR11029B

Protofibrils, pores, fibrils, and neurodegeneration: separating the responsible protein aggregates from the innocent bystanders

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NR11029B

A structural model for Alzheimer's beta -amyloid fibrils based on experimental constraints from solid state NMR

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NR11029B

3D structure of Alzheimer's amyloid-beta(1-42) fibrils

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NR11029B

Copper(II) binding to amyloid-beta fibrils of Alzheimer's disease reveals a picomolar affinity: stoichiometry and coordination geometry are independent of Abeta oligomeric form

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NR11029B

Protein conformational misfolding and amyloid formation: characteristics of a new class of disorders that include Alzheimer's and Prion diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NR11029B

Protein misfolding, functional amyloid, and human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NR11029B

Amyloid ion channels: a common structural link for protein-misfolding disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NR11029B

Effects of lactose permease of Escherichia coli on the anisotropy and electrostatic surface potential of liposomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NR11029B

Cholesterol is an important factor affecting the membrane insertion of beta-amyloid peptide (A beta 1-40), which may potentially inhibit the fibril formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NR11029B

Probing copper2+ binding to the prion protein using diamagnetic nickel2+ and 1H NMR: the unstructured N terminus facilitates the coordination of six copper2+ ions at physiological concentrations

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NR11029B

Deconvoluting the Cu2+ binding modes of full-length prion protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NR11029B

The Aβ Peptide of Alzheimer's Disease Directly Produces Hydrogen Peroxide through Metal Ion Reduction†

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC1NR11029B

21 January 2018

Identifiers

DOI

10.1039/C1NR11029B

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12 September 2017

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