(Q39947061)

15 September 2017

title

Sequestration of copper from beta-amyloid promotes selective lysis by cyclen-hybrid cleavage agents (English)

1 reference

15 September 2017

0 references

2

1 reference

15 September 2017

11

1 reference

15 September 2017

Adam P Gunn

5

0 references

author name string

Wei-hui Wu

1

1 reference

15 September 2017

Qian Liu

3

1 reference

15 September 2017

Jia Hu

4

1 reference

15 September 2017

Mei-sha Chen

6

1 reference

15 September 2017

Yan-fang Rui

7

1 reference

15 September 2017

Xiao-yang Su

8

1 reference

15 September 2017

Zuo-ping Xie

9

1 reference

15 September 2017

Yu-Fen Zhao

10

1 reference

15 September 2017

Yan-mei Li

12

1 reference

15 September 2017

language of work or name

English

0 references

publication date

26 August 2008

1 reference

Journal of Biological Chemistry

15 September 2017

published in

1 reference

15 September 2017

volume

283

1 reference

15 September 2017

issue

46

1 reference

15 September 2017

page(s)

31657-31664

1 reference

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

15 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804722200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804722200

Twenty years of the Alzheimer's disease amyloid hypothesis: a genetic perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804722200

Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804722200

Copper, beta-amyloid, and Alzheimer's disease: tapping a sensitive connection

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804722200

Enhanced proteolysis of beta-amyloid in APP transgenic mice prevents plaque formation, secondary pathology, and premature death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804722200

Antiamyloidogenic and neuroprotective functions of cathepsin B: implications for Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804722200

100 years and counting: prospects for defeating Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804722200

Metalloenzyme-like activity of Alzheimer's disease beta-amyloid. Cu-dependent catalytic conversion of dopamine, cholesterol, and biological reducing agents to neurotoxic H(2)O(2).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804722200

Tyrosine gated electron transfer is key to the toxic mechanism of Alzheimer's disease beta-amyloid

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804722200

Copper, iron and zinc in Alzheimer's disease senile plaques.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804722200

Metal binding and oxidation of amyloid-beta within isolated senile plaque cores: Raman microscopic evidence

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804722200

Strategies for disease modification in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804722200

Metal-protein attenuation with iodochlorhydroxyquin (clioquinol) targeting Abeta amyloid deposition and toxicity in Alzheimer disease: a pilot phase 2 clinical trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804722200

Cleavage agents for soluble oligomers of amyloid beta peptides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804722200

Synthetic artificial peptidases and nucleases using macromolecular catalytic systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804722200

Curcumin inhibits formation of amyloid beta oligomers and fibrils, binds plaques, and reduces amyloid in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804722200

Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804722200

Copper binding to the amyloid-beta (Abeta) peptide associated with Alzheimer's disease: folding, coordination geometry, pH dependence, stoichiometry, and affinity of Abeta-(1-28): insights from a range of complementary spectroscopic techniques

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804722200

L-type calcium channels and GSK-3 regulate the activity of NF-ATc4 in hippocampal neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804722200

Binding of Zn(II), Cu(II), and Fe(II) ions to Alzheimer's A beta peptide studied by fluorescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804722200

Cu(II) potentiation of alzheimer abeta neurotoxicity. Correlation with cell-free hydrogen peroxide production and metal reduction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804722200

Spherical aggregates of beta-amyloid (amylospheroid) show high neurotoxicity and activate tau protein kinase I/glycogen synthase kinase-3beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804722200

A specific amyloid-beta protein assembly in the brain impairs memory

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804722200

NMDA receptor activation mediates copper homeostasis in hippocampal neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804722200

Dramatic aggregation of Alzheimer abeta by Cu(II) is induced by conditions representing physiological acidosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804722200

Excess brain protein oxidation and enzyme dysfunction in normal aging and in Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804722200

Copper-mediated amyloid-beta toxicity is associated with an intermolecular histidine bridge.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804722200

Membrane-mediated amyloidogenesis and the promotion of oxidative lipid damage by amyloid beta proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804722200

Synchrotron-based infrared and X-ray imaging shows focalized accumulation of Cu and Zn co-localized with beta-amyloid deposits in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804722200

Aqueous dissolution of Alzheimer's disease Abeta amyloid deposits by biometal depletion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804722200

Treatment with a copper-zinc chelator markedly and rapidly inhibits beta-amyloid accumulation in Alzheimer's disease transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804722200

The lipophilic metal chelator DP-109 reduces amyloid pathology in brains of human beta-amyloid precursor protein transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804722200

Nicotine attenuates beta-amyloid-induced neurotoxicity by regulating metal homeostasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804722200

Rapid restoration of cognition in Alzheimer's transgenic mice with 8-hydroxy quinoline analogs is associated with decreased interstitial Abeta

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804722200

Safety, efficacy, and biomarker findings of PBT2 in targeting Abeta as a modifying therapy for Alzheimer's disease: a phase IIa, double-blind, randomised, placebo-controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804722200

A native to amyloidogenic transition regulated by a backbone trigger

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804722200

The Aβ Peptide of Alzheimer's Disease Directly Produces Hydrogen Peroxide through Metal Ion Reduction†

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M804722200

21 January 2018

Identifiers

DOI

10.1074/JBC.M804722200

1 reference

15 September 2017

1 reference