(Q39540572)

12 September 2017

title

TCR down-regulation boosts T-cell-mediated cytotoxicity and protection against poxvirus infections (English)

1 reference

12 September 2017

0 references

8

Carsten Geisler

0 references

Niels Ødum

6

Niels Ødum

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Marina Rode von Essen

9

Marina R von Essen

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Charlotte Menné Bonefeld

Charlotte M Bonefeld

3

0 references

Lasse Boding

4

Lasse Boding

1 reference

12 September 2017

5

Martin Kongsbak

1 reference

12 September 2017

Ann K Hansen

1

1 reference

12 September 2017

Matthias Regner

2

1 reference

12 September 2017

Niels Ødum

6

1 reference

12 September 2017

Arno Müllbacher

7

1 reference

12 September 2017

Marina R von Essen

9

1 reference

12 September 2017

language of work or name

English

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publication date

27 May 2011

1 reference

European Journal of Immunology

12 September 2017

published in

1 reference

12 September 2017

volume

41

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12 September 2017

issue

7

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12 September 2017

page(s)

1948-1957

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Effector and memory CTL differentiation

12 September 2017

cites work

1 reference

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The lytic granules of natural killer cells are dual-function organelles combining secretory and pre-lysosomal compartments

21 January 2018

1 reference

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Cytotoxic T lymphocyte granules are secretory lysosomes, containing both perforin and granzymes

21 January 2018

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Secretory mechanisms in cell-mediated cytotoxicity

21 January 2018

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Centrosome polarization delivers secretory granules to the immunological synapse.

21 January 2018

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Shouts, whispers and the kiss of death: directional secretion in T cells

21 January 2018

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Functional significance of the perforin/granzyme cell death pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201141413

Degranulation plays an essential part in regulating cell surface expression of Fas ligand in T cells and natural killer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201141413

CTLs contain and use intracellular stores of FasL distinct from cytolytic granules

21 January 2018

1 reference

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The TNF and TNF receptor superfamilies: integrating mammalian biology

21 January 2018

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Antigen-dependent release of IFN-gamma by cytotoxic T cells up-regulates Fas on target cells and facilitates exocytosis-independent specific target cell lysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201141413

The strength of T cell receptor signal controls the polarization of cytotoxic machinery to the immunological synapse

21 January 2018

1 reference

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Kinetics of early T cell receptor signaling regulate the pathway of lytic granule delivery to the secretory domain

21 January 2018

1 reference

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The duration of TCR/pMHC interactions regulates CTL effector function and tumor-killing capacity.

21 January 2018

1 reference

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TCR trafficking in resting and stimulated T cells

21 January 2018

1 reference

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Cbl promotes ubiquitination of the T cell receptor zeta through an adaptor function of Zap-70.

21 January 2018

1 reference

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Molecular characterization of the di-leucine-based internalization motif of the T cell receptor

21 January 2018

1 reference

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Regulation and function of the CD3gamma DxxxLL motif: a binding site for adaptor protein-1 and adaptor protein-2 in vitro.

21 January 2018

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The Phosphorylation State of CD3γ Influences T Cell Responsiveness and Controls T Cell Receptor Cycling

21 January 2018

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Leucine-based receptor sorting motifs are dependent on the spacing relative to the plasma membrane

21 January 2018

1 reference

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Endo- and exocytic rate constants for spontaneous and protein kinase C-activated T cell receptor cycling

21 January 2018

1 reference

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The CD3 gamma leucine-based receptor-sorting motif is required for efficient ligand-mediated TCR down-regulation

21 January 2018

1 reference

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TCR comodulation of nonengaged TCR takes place by a protein kinase C and CD3 gamma di-leucine-based motif-dependent mechanism

21 January 2018

1 reference

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TCR down-regulation controls virus-specific CD8+ T cell responses

21 January 2018

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Viral escape by selection of cytotoxic T cell-resistant virus variants in vivo

21 January 2018

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Molecular analysis of the antigen receptor of virus-specific cytotoxic T cells and identification of a new V alpha family

21 January 2018

1 reference

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TCR down-regulation controls T cell homeostasis.

21 January 2018

1 reference

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Granzymes are the essential downstream effector molecules for the control of primary virus infections by cytolytic leukocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201141413

Cell-mediated cytotoxicity in recovery from poxvirus infections

21 January 2018

1 reference

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Induction of natural killer cell responses by ectromelia virus controls infection

21 January 2018

1 reference

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Synergistic signals for natural cytotoxicity are required to overcome inhibition by c-Cbl ubiquitin ligase

21 January 2018

1 reference

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Defective granule exocytosis in Rab27a-deficient lymphocytes from Ashen mice

21 January 2018

1 reference

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Genetic defects affecting lymphocyte cytotoxicity

21 January 2018

1 reference

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T cell activation determined by T cell receptor number and tunable thresholds.

21 January 2018

1 reference

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The Cbl family and other ubiquitin ligases: destructive forces in control of antigen receptor signaling

21 January 2018

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Negative regulation of lymphocyte development and function by the Cbl family of proteins

21 January 2018

1 reference

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An amphibian CD3 homologue of the mammalian CD3 gamma and delta genes

21 January 2018

1 reference

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Cytotoxic lymphocytes require granzyme B for the rapid induction of DNA fragmentation and apoptosis in allogeneic target cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201141413

Virulence of mousepox virus is independent of serpin-mediated control of cellular cytotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201141413

Identification of poxvirus CD8+ T cell determinants to enable rational design and characterization of smallpox vaccines

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201141413

Constitutive and ligand-induced TCR degradation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201141413

Cytotoxic T lymphocytes: all roads lead to death

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201141413

inferred from DOI database lookup

7 January 2021

based on heuristic

Activation of the Lck tyrosine kinase targets cell surface T cell antigen receptors for lysosomal degradation

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201141413

inferred from DOI database lookup

7 January 2021

based on heuristic

Perforin is essential for control of ectromelia virus but not related poxviruses in mice.

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201141413

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1002/EJI.201141413

1 reference

12 September 2017

1 reference